Results 171 to 180 of about 2,364,688 (269)

Reversal of Chronic Stress‐Induced Inflammaging by Bazi Bushen Formula Through AMPK‐Sirtuins Axis Activation and Myeloid Reset

Exploration, EarlyView.
Chronic stressors trigger systemic immune remodeling marked by myeloid expansion and lymphoid suppression, and this immune imbalance subsequently drives tissue pathology through proinflammatory signaling and senescence amplification, with the lung and kidney confirmed as the most vulnerable target organs.
Mengnan Li, Zheming Chen, Lu Wang, Zixuan Wang, Shixiong Zhang, Kunxu Niu, Xiaogang Shen, Xuan Lu, Runtao Zhang, Yuning Jiang, Yawen Li, Yi Dai, Xiyang Tang, Bin Hou, Min Shi, Xiaoya Wang, Zhifang Guo, Xingyu Xing, Ning Kang, Hongrong Li, Tianyu Kang, Evelyne Bischof, Yunlong Hou, Zhenhua Jia   +23 more
wiley   +1 more source

Fluorescence‐Guided Detection of Perineural and Bony Invasion With Margin Correlation in Gingival Squamous Cell Carcinoma Using Panitumumab‐IRDye800

Head &Neck, EarlyView.
ABSTRACT Background Near‐infrared (NIR) fluorescence‐guided surgery using EGFR‐targeted tracers (e.g., panitumumab‐IRDye800CW) can provide real‐time visualization of tumors and margins in Head and Neck Squamous Cell Carcinoma. Prior studies have demonstrated its safety and potential to improve intraoperative decision‐making and margin assessment ...
Makenna Brown, Mabrooka Kazi, Hidenori Tanaka, Brandee Brown, Mitra Mehrad, Sarah Rohde, Eben Rosenthal, Kyle Mannion   +7 more
wiley   +1 more source

Retrospective analysis of outcome after endometrial ablation with the NovaSure device: A German single‐center experience

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Evaluation of retrospective outcomes of NovaSure treatment in patients with abnormal uterine bleeding, including safety and cost‐effectiveness, and risk factors related to therapeutic outcomes. Subgroup analysis was conducted for patients who underwent concomitant surgical procedures, required subsequent interventions, and were ...
Oliver M. Schleicher, Felix Heindl, Julia Gocke, Katharina Keller, Lothar Häberle, Alaa Hamzeh, Christian Matek, Matthias W. Beckmann, Julius Emons   +8 more
wiley   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Demineralized bone allograft fibers versus particulate in sinus augmentation: A double‐arm randomized controlled and histomorphometric study

Journal of Periodontology, EarlyView.
Abstract Background The primary aim of this study was to evaluate histologic wound healing of demineralized freeze‐dried bone allograft (DFDBA), in particulate (P) or fiber (F) form, in combination with deproteinized bovine bone mineral (DBBM) for maxillary sinus floor augmentation.
Kathryn Gabel, Brian L. Mealey, Michael Mills, Archontia A. Palaiologou   +3 more
wiley   +1 more source

Olaparib Blocks Oxidative Stress‐Dependent NLRP3 Inflammasome in Pediatric Acute Lung Injury by Metabolic Reprogramming via AMPK‐Driven Autophagic Flux

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Pediatric acute lung injury (ALI) is a life‐threatening syndrome defined by dysregulated pulmonary inflammation and impaired alveolar gas exchange, with limited therapeutic interventions. This study aims to evaluate the therapeutic efficacy and mechanistic basis of Olaparib, a clinically approved PARP inhibitor, using in vitro and in vivo ...
Fen Gong, Mei‐Ling Yu, Zheng‐Rong Chen, Mei Li, Xu Sang, Yong‐Dong Yan   +5 more
wiley   +1 more source

EHR‐Integrated Synoptic Operative Reporting for Head and Neck Oncologic Surgery

The Laryngoscope, EarlyView.
EHR‐integrated synoptic operative templates for head and neck oncologic surgery was developed and implemented at a tertiary academic cancer center. Departmental adherence rose from 49% to nearly 80% over 6 months, and 94.5% of reviewed cases met targets for complete, internally consistent documentation. The resulting structured data dictionary provides
Miriam N. Lango, Avery Sinnathamby, Marc‐Elie Nader, Paul W. Gidley, Karen Y. Choi, Mark Zafereo, Carly E. A. Barbon, Kristen B. Pytynia, Anastasios Maniakas, Amy Hessel, Ryan P. Goepfert, Faisal I. Ahmad, Jennifer L. Anderson, Sahil K. Kapur, Jolyn S. Taylor   +14 more
wiley   +1 more source

Fretting Wear and Corrosion Behavior of the Fe‐35Mn Biodegradable Alloy for Biomedical Applications

Materials and Corrosion, EarlyView.
This study evaluates the corrosion and tribological wear behavior of the Fe‐35Mn alloy, demonstrating superior mechanical stability and a more favorable degradation rate than pure iron, thereby highlighting its potential for biomedical applications. ABSTRACT The biodegradable Fe‐35Mn alloy has emerged as a promising material for temporary implants due ...
Kerolene Barboza da Silva, Caio Pascotti Valem, S. Sudhagara Rajan, Vasanth Gopal, Praveenkumar Kesavan, Roberto Zenhei Nakazato, Geetha Manivasagam, Ana Paula Rosifini Alves   +7 more
wiley   +1 more source

Recent Advances in Exosome‐Based Nanodelivery Systems for Traumatic Brain Injury Treatment

Med Research, EarlyView.
An overview of functional modification, therapeutic effects, molecular composition, and delivery strategies for exosomes. ABSTRACT Traumatic brain injury (TBI) is a highly heterogeneous neurological condition with extremely high rates of mortality and disability.
Jue Zhu, Weiquan Liao, Ziqi Lian, Mengdan Zhang, Chenxing Wang, Xingjia Zhu, Lin Zhang, Jian Chen, Zhichao Lu, Peipei Gong   +9 more
wiley   +1 more source

Let's Talk About Bone Cylinders. Taphonomy of Carnivores and Humans

International Journal of Osteoarchaeology, EarlyView.
ABSTRACTBone cylinders are a distinctive structure predominantly produced by durophagous carnivoran species during the consumption of long bones, in which the diaphyseal canal remains intact while both epiphyses are removed or consumed. This study evaluates the significance of this morphology, traditionally attributed to extant and extinct hyena ...
Darío Herranz‐Rodrigo
wiley   +1 more source