Results 51 to 60 of about 59,676 (296)

Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells

open access: yesAdvanced Science, EarlyView.
ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen   +11 more
wiley   +1 more source

Occlusal vertical dimension: Effect on esthetic norms at smile

open access: yesIndian Journal of Dental Sciences, 2018
Background and Objectives: The restorative and esthetic needs for the complete mouth rehabilitation patient frequently require an increase in occlusal vertical dimension (OVD), in whom there would be tooth loss or attrition in existing teeth, decreased ...
Aayesha Razzaque   +5 more
doaj   +1 more source

Multi‐Enzyme Mimetic Molybdenum Nitride Nanozymes Reshape Subgingival Microenvironment for Synergistic Periodontitis Therapy via ROS Regulation and Microbiome Remodeling

open access: yesAdvanced Science, EarlyView.
ABSTRACT Periodontitis, a chronic inflammatory disease initiated and sustained by plaque microorganisms and host immune response, remains an intractable oral disease and a leading cause of tooth loss worldwide. Traditional mechanical debridement and adjunctive antibiotic or antiseptic therapy often shows limited efficacy due to the complex anatomical ...
Weiyu Zhang   +12 more
wiley   +1 more source

Identifying Dental and Oral Health Problems of Kindergarteners using KAFOGI Dental Photography

open access: yesIndonesian Journal of Dental Medicine, 2020
Background: Caries is one of the most common dental and oral health problems in preschool students. An epidemiological study reported that students of a kindergarten under Mojo Public Health Center coverage have a high caries index (def 6.9).
Muhammad Bima Rizki Dwitama   +11 more
doaj   +1 more source

Front and Center [PDF]

open access: yes, 1970
Newsletter providing "a lighter, human interest side of the news" from the Boston University Medical ...
Boston University Medical Center   +2 more
core  

Impact of paracetamol pack size restrictions on poisoning from paracetamol in England and Wales: an observational study.

open access: yes, 2005
BACKGROUND: About 500 drug poisoning deaths involving paracetamol (acetaminophen) occur every year in England and Wales. To reduce the number of deaths, regulations were introduced in 1998 to restrict the sale of paracetamol.
Griffiths, Clare   +2 more
core   +1 more source

An Implanted Tooth That Can Feel

open access: yesAdvanced Science, EarlyView.
To endow the implanted tooth with masticatory perception, herein we demonstrate that a 3D‐printed piezoelectric‐core/robust‐sheath implanted tooth can rebuild the sensing feedback, serving as “mechanoreceptors” in converting the mechanical chewing force to electrical signals, and up to brain through surrounding alveolar nerve system.
Yaru Cao   +13 more
wiley   +1 more source

Spartan Daily, March 7, 1994 [PDF]

open access: yes, 1994
Volume 102, Issue 27https://scholarworks.sjsu.edu/spartandaily/8527/thumbnail ...
San Jose State University, School of Journalism and Mass Communications
core   +1 more source

Development‐based In Vivo Bioreactor Strategy for Challenging Senescent Bone Reconstruction

open access: yesAdvanced Science, EarlyView.
We present a development‐based in vivo bioreactor strategy to generate rejuvenated bone grafts (vBR‐Bone) within aged hosts. By enclosing vBR‐Bone fragments within an asymmetric biomimetic periosteum, segmental femoral defects in aged mice were successfully repaired within 6 weeks. Mechanistically, the multifactors of vBR‐Bone reconstitute a remodeling
Wenchao Zhang   +9 more
wiley   +1 more source

Multi-Class Malocclusion Detection on Standardized Intraoral Photographs Using YOLOv11

open access: yesDentistry Journal
Background/Objectives: Accurate identification of dental malocclusions from routine clinical photographs can be time-consuming and subject to interobserver variability.
Ani Nebiaj   +3 more
doaj   +1 more source

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