Results 91 to 100 of about 24,542 (252)

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

A New Paradigm: 46 Structural Cell Types Function as Environment‐Supporting Innate Immune Cells, With Endothelial and Vascular Smooth Muscle Cells as Key Prototypes

iNew Medicine, EarlyView.
ABSTRACT The scope, organization, and biological significance of innate immune functions across structural cell types remain poorly defined. To address these fundamental knowledge gaps, we analyzed experimental data of transcriptomes generated by our group and others.
Juanjuan Liu, Gayani K. Nanayakkara, Yifan Lu, Fatma Saaoud, Keman Xu, Ying Shao, Bo Yuan, Shih‐Yu Hung, Haiyan Xiang, Xianwei Wang, Sadia Mohsin, Sheng Wu, Xiaolei Liu, Juncheng Wei, Zhengjie Zhou, Beata Kosmider, Mingui Fu, Laisel Martinez, Roberto Vazquez‐Padron, Wenhui Hu, Shuping Ge, Hong Wang, Xiaofeng Yang   +22 more
wiley   +1 more source

Ordered assembly of Cas12a for better performance of CRISPR/Cas system with application to the diagnosis of dental caries

Interdisciplinary Medicine, EarlyView.
Here, we present a tetrahedral DNA framework (TDF)‐mediated Cas12a ordered assembly strategy. TDFs arrange CRISPR/Cas12a into ordered structures controllably, enhancing catalytic efficiency through localized Cas12a hotspots while maintaining spatial intervals to facilitate substrate diffusion.
Yining Zhao, Panpan Qiao, Yujing Zeng, Murtaza Sayed, Qin Mi, Juan Zhang, Genxi Li   +6 more
wiley   +1 more source

Prevalence of Plaque Induced Gingivitis Among Dental Students in College of Dentistry, Hawler Medical University.

Erbil Dental Journal
Background and objective: Gingival inflammation in response to bacterial plaque accumulation is considered the key risk factor for the onset of periodontitis.
Zainab Salim Mahmood, Qehraman Ismayil Ahmed, Ahmed Luqman Saifullah   +2 more
doaj  

Single‐Cell Profiling Identifies CLEC5A+ Macrophages as Key Drivers of Thoracic Aortic Aneurysm Via CCL5‐Mediated M1 Polarization

Journal of Clinical Laboratory Analysis, EarlyView.
Thoracic aortic aneurysm (TAA) is a life‐threatening cardiovascular disease with limited therapeutic options. Through single‐cell RNA sequencing of aortic tissues from healthy individuals and TAA patients (105,541 cells), we identified CLEC5A+macrophages as the predominant pathogenic cell population exhibiting the highest M1 polarization score. Machine
Xiangyu Li, Chunguang Guo, Mingyao Luo, Chang Shu   +3 more
wiley   +1 more source

The Reality and Direction of Korean Dental Hygiene Education in the Super‐Aged Society

Journal of Dental Education, EarlyView.
ABSTRACT Objectives This study aims to analyze the structural features and key issues of dental hygiene education and the national licensing examination in response to a super‐aged society. To this end, the current status and challenges of Korea's dental hygiene education system are reviewed, and comparative analyses of corresponding systems in the ...
Ji‐Won Choi, Jeewan Chun, Sang‐Hwan Oh   +2 more
wiley   +1 more source

Effect of sugar-free gum in addition to tooth brushing on dental plaque and interdental debris

Dental Research Journal, 2010
Background: Chewing-gum may serve as an effective oral hygiene device when brushing may not be possible. The aim of the present study was to evaluate the effect of chewing sugar-free gum twice a day after meals in addition to tooth brushing on dental ...
Pradnya Kakodkar, Soniya Mulay
doaj  

Biomaterials for resolution of peri‐implantitis: Consensus report of Workgroup 2 of the IADR Implantology Research Group Best Evidence Consensus Symposium on Peri‐Implant Disease and Its Treatment

Journal of Periodontology, EarlyView.
Abstract Background Peri‐implantitis is a destructive disease affecting the tissues surrounding dental implants. Biomaterials may be applied during surgical treatment to reconstruct bony defects and support soft tissue healing. However, current evidence is unclear if these treatments increase the likelihood of peri‐implantitis resolution.
Sukirth M. Ganesan, David R. Fraser, Mustafa Tattan, Jessica M. Latimer, IADR IRG Peri‐Implantitis Best Evidence Consensus Working Group 2, Mario Aimetti, Hatice Hasturk, Purnima S. Kumar, Fernando Suarez Lopez Del Amo, Andreas Stavropoulos, Daniel S. Thoma, Spyridon Vassilopoulos, Hom‐Lay Wang, Georgios Kotsakis   +13 more
wiley   +1 more source

Clinical evaluation of an ionic tooth brush on oral hygiene status, gingival status, and microbial parameter

Indian Journal of Dental Research, 2006
It has long been recognised that the presence of dental plaque leads to gingivitis and periodontal disease, as well as dental caries. Today tooth brushing is the most widely accepted method of removing plaque.
Deshmukh J, Vandana K, Chandrashekar K, Savitha B   +3 more
doaj  

Effectiveness of nonsurgical re‐instrumentation of residual pockets as step 3 of periodontal therapy: A field study

Journal of Periodontology, EarlyView.
Abstract Background The study aims to analyze the effectiveness of nonsurgical re‐instrumentation of residual pockets as step 3 of periodontal therapy and the stability of treatment outcomes at 18 months. Methods The study sample consisted of 489 patients diagnosed and treated nonsurgically for periodontitis.
Anna Liss, Kajsa H. Abrahamsson, Maria Welander, Cristiano Tomasi   +3 more
wiley   +1 more source