Results 41 to 50 of about 25,916 (251)

Co‐activation of Selective Nicotinic Acetylcholine Receptor Subtypes Is Required for Neuroprotection against Alzheimer's Disease

Advanced Science, EarlyView.
ABSTRACT Beta‐amyloid peptide (Aβ)‐induced suppression of hippocampal GABAergic interneuron activity drives hyperexcitability, amyloid pathology, and cognitive impairment in Alzheimer's disease (AD), suggesting that enhancing hippocampal inhibition may be protective.
Rahmi Lee, Gayeon Kim, Ellison R. Black, Seonil Kim   +3 more
wiley   +1 more source

Helicobacter pylori in the dental plaque of healthy Saudis

The Saudi Journal of Gastroenterology, 1998
The objective of this study is to determine the presence of Helicobacter pylori in the dental plaque of healthy Saudis and its relation to dental care.
Contractor Qais, Tahir Mohammed, Naseem Shahzad, Ahmad Shamweel   +3 more
doaj  

A Personalised 3D-Printed Dental Plaque Removal Mouthguard for Older Adults

International Dental Journal, 2023
Objectives: The aim of the present study was to examine the plaque removal effectiveness of a personalised 3D-printed dental plaque removal mouthguard device in a clinical trial setting.
Hao Ding, Meng Zhang, Brian Lo, Karfield K.F. Chan, Edward C.M. Lo, James K.H. Tsoi   +5 more
doaj   +1 more source

Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism

Advanced Science, EarlyView.
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He, Yuwen Wang, Jonathan F. Gong, Yiting Lei, Fei Jin, Weihong Zhu, Rocky S. Tuan, Zhong Alan Li   +7 more
wiley   +1 more source

ORAL HEALTH STATUS OF A GROUP OF ASTHMATIC CHILDREN IN ALEXANDRIA, EGYPT (CROSS-SECTIONAL STUDY) [PDF]

Alexandria Dental Journal
AIM: To evaluate and compare dental caries, erosion, dental plaque, and gingival health status between a group of asthmatic and non-asthmatic children in Alexandria, Egypt.METHODS: In this cross-sectional study, 88 children were selected according to the
Zainab ALQassab, Karin Dowidar, Reham Soliman   +2 more
doaj   +1 more source

Clinical Trial Data on the Mechanical Removal of 14-Day-Old Dental Plaque Using Accelerated Micro-Droplets of Air and Water (Airfloss)

Data, 2023
Novel strategies to combat dental biofilms aim at reducing biofilm stability with the ultimate goal of facilitating mechanical cleaning. To test the stability of dental biofilms, they need to be subjected to a defined mechanical stress. Here, we employed
Yumi C. Del Rey, Pernille D. Rikvold, Karina K. Johnsen, Sebastian Schlafer   +3 more
doaj   +1 more source

Restores Aβ Clearance by Overcoming PCSK9–LRP1 Dysregulation and TRIB3‐Mediated Autophagy Blockade in Alzheimer's Disease

Advanced Science, EarlyView.
PCSK9 upregulation in cerebrovascular endothelial cells and microglia destabilizes the Aβ transporter LRP1, while TRIB3‐associated autophagy blockade further limits intracellular Aβ degradation. A RAP‐modified tea‐polyphenol nanoparticle co‐delivers siPCSK9 and siTRIB3 to restore LRP1‐mediated Aβ efflux and autophagy‐dependent degradation, reducing Aβ ...
Jie Miao, Jing Wang, Yankun Li, Haipei Zhang, Yanli Zhang, Qingnian Li, Bo Xiao, Wenhu Zhou, Junhong Guo   +8 more
wiley   +1 more source

The potential of toothpaste containing Robusta coffee bean extract in reducing gingival inflammation and dental plaque formation

Dental Journal, 2023
Background: The prevention of gingivitis using chemicals containing antibiotics and chlorhexidine can disrupt the balance of the oral microbiota and have side effects in long-term use.
Peni Pujiastuti, Neira Najatus Sakinah, Yuliana Mahdiyah Da’at Arina, Melok Aris Wahyukundari, Depi Praharani, Desi Sandra Sari   +5 more
doaj   +1 more source

Salivary Citrate Deficiency Defines an Endogenous Dentin Remineralization Failure State Through Glandular MT1/2‐Zn2+‐ACO2 Dysregulation

Advanced Science, EarlyView.
Salivary citrate deficiency in early‐stage Sjögren's syndrome accompanies impaired dentin remineralization despite preserved salivary flow and mineral availability. Matched‐ion experiments reveal disrupted mineral organization and reduced dentin recovery at disease‐associated citrate levels.
Ran You, Wenhui Wang, Franklin R. Tay, Haotian Dong, Mutong Wei, Ruoyun Wu, Xin Song, Chen Chen, Haifeng Xie   +8 more
wiley   +1 more source

Correlation of plaque nitric oxide levels with plaque Streptococcus mutans, plaque pH and decayed, missing and filled teeth index of children of different age groups

Journal of Indian Society of Pedodontics and Preventive Dentistry, 2016
Context: Dental plaque is considered one of the most important etiological factors for dental caries. Nitrate and Nitrite levels in saliva are considered protective against oral and gastrointestinal disease.
Sawinderjit Saini, Hina Noorani, P K Shivaprakash   +2 more
doaj   +1 more source