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Stem Cells of the Dental Pulp

2014
Dental Pulp Stem Cells (DPSCs) can be found within the cell rich zone of dental pulp. These stem cells, under specific stimuli, differentiate into many cell types which have wide therapeutic applications.   The dental stem cells are derived from both deciduous and permanent teeth.
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Cellular senescence in dental pulp stem cells

Archives of Oral Biology, 2019
This short review summarizes our current knowledge about dental stem cell aging and about possible targets for the regulation of cellular senescence.A literature search was performed using a combination of keywords, e.g., stem cells, replicative senescence, differentiation potential, dental pulp, dental follicle and periodontal ligament.Previous ...
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Dental pulp stem cells and regeneration

Endodontic Topics, 2013
Dental pulp‐derived stem cells (DPSCs) are considered to be of great promise for use in tissue repair and regenerative medicine. DPSCs can easily be collected from discarded teeth with little ethical concerns and harvested in a minimally invasive and safe manner.
Misako Nakashima   +2 more
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Induced Migration of Dental Pulp Stem Cells for in vivo Pulp Regeneration

Journal of Dental Research, 2011
Dental pulp has intrinsic capacity for self-repair. However, it is not clear whether dental pulp cells can be recruited endogenously for regenerating pulp tissues, including mineralizing into dentin. This work is based on a hypothesis that dental pulp stem/progenitor cells can be induced to migrate by chemotactic cytokines and act as endogenous cell ...
T, Suzuki   +9 more
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Pulp Regeneration by 3-dimensional Dental Pulp Stem Cell Constructs

Journal of Dental Research, 2018
Dental pulp regeneration therapy for the pulpless tooth has attracted recent attention, and clinical trial studies are underway with the tissue engineering approach. However, there remain many concerns, including the extended period for regenerating the dental pulp. In addition, the use of scaffolds increases the risk of inflammation and infection.
Y. Itoh   +5 more
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Dental Pulp Stem Cells in Pulp Regeneration

SunText Review of Medical & Clinical Research, 2021
Saberian E   +3 more
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Dental Pulp Stem Cell Niche

2015
Dental stem cells exist in dental tissues. Of those that have been isolated and better studied are those reside in dental pulp. These dental tissue-derived mesenchymal stem/stromal cells (MSCs) shared similar characteristics to other MSCs , yet, they are subtly different.
Jinhua Yu   +3 more
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Dental Stem Cells for Pulp Regeneration

2016
The management of pathological conditions of the dental pulp is mainly based on the disinfection of root canal system followed by the replacement of the infected or inflamed pulp tissues by inert materials. In immature teeth, the routine root canal treatment often limits the completion of root formation and protection against external root resorption ...
Nileshkumar Dubey   +2 more
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[The characteristics of cultured dental pulp cells and the localization of dental pulp stem cells].

Shanghai kou qiang yi xue = Shanghai journal of stomatology, 2004
This study was aimed to investigate the localization of dental pulp stem cells (DPSCs) by comparing the characteristics of cultured dental pulp cells in coronal and root pulp.Human dental coronal and root pulp cells were cultured in tissue-explant method, the cell culture successfulness, attachment efficiency, cell viality, morphology, proliferation ...
Shao-hua, Liu   +4 more
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Effects of simulated microgravity on dental pulp stem cell stemness

Journal of Molecular Histology
Dental pulp stem cells (DPSCs), a subset of tooth-derived mesenchymal stem cells (MSCs), demonstrate significant promise in clinical stem cell therapy. However, prolonged in vitro expansion commonly results in compromised stemness, limiting therapeutic efficacy. Thus, maintaining the stemness of DPSCs during expansion and culture is a key challenge for
Huailong, Hou   +10 more
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