Results 51 to 60 of about 1,036,021 (299)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Research Publication Challenges Faced by Dentists in India: A Narrative Review of Multilevel Barriers [PDF]

Journal of Clinical and Diagnostic Research
Research articles are essential for achieving academic excellence, frequently impacting career progression, funding opportunities, and the prestige of educational Institutions.
K Saran, G Krishnaprakash, Sibyl Siluvai, Kp Indumathi   +3 more
doaj   +1 more source

Research policy and organization in dental research [PDF]

European Journal of Oral Sciences, 1973
Peer Reviewed ; http://deepblue.lib.umich.edu/bitstream/2027.42/73336/1/j.1600-0722.1973.tb00354.x ...
openaire   +3 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

HUBUNGAN PENGETAHUAN, SIKAP DAN PRAKTIK KESEHATAN GIGI DAN MULUT TERHADAP KEJADIAN KARIES GIGI (STUDI KASUS PADA SD MLATI I DAN SD SENDANG ADI I KECAMATAN MLATI KABUPATEN SLEMAN YOGYAKARTA [PDF]

, 2006
Gigi karies yang mempengaruhi proses pengunyahan makanan dalam mulut sehingga pemenuhan gizi akan berkurang. Hasil penelitian di Yogyakarta melaporkan bahwa karies gigi sulung di 100 taman kanak-kanak sebesar 85%, tanpa menyebutkan indek def-tnya. Profil
RUMINI, EVI
core  

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Collaborative Instruction for Information Retrieval and Appraisal Skills in Evidence-Based Practice Models for Dental Hygiene Students. [PDF]

, 2017
Objectives: 1. Collaborate with VCU Dental Hygiene Program faculty to develop and evaluate a model of evidence-based practice (EBP) for students in didactic and clinical settings. 2. Describe how a course was modified to emphasize evidence-based practice.
Lubker, Irene M, Pellegrini, Joan M.
core   +1 more source

A protocol for a systematic review of clinical guidelines and published systematic reviews on the early detection of oral cancer [PDF]

, 2016
Background: The predicted increase in incidence of oral cavity cancer (OCC) coupled with high mortality and poor prognosis – particularly when diagnosed at a late/advanced stage – highlights the need for prevention and early detection/screening to ...
Al Bulushi, Naeema M., Conway, David I., Gibson, John, Macpherson, Lorna M.D., Ross, Alastair J., Worlledge-Andrew, Heather   +5 more
core   +1 more source

Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini, Alessia Casarini, Niccolò Biagioli, Laura Mirandola, Daniela Ballotta, Paul Summers, Simona Scolastico, Laura Madrassi, Maurilio Genovese, Marcella Malagoli, Gaetano Cantalupo, Giada Giovannini, Matteo Pugnaghi, Niccolò Orlandi, Laura Tassi, Valeria Cuccarini, Domenico Aquino, Elena Tartara, Fulvia Palesi, Giuseppe Didato, Paolo Vitali, the 3TLE Study Group, Roberta Di Giacomo, Fabio Doniselli, Federica Mazzi, Carlo Andrea Galimberti, Claudia A. M. Gandini Wheeler‐Kingshott, Stefano Meletti, Anna Elisabetta Vaudano   +28 more
wiley   +1 more source