Results 191 to 200 of about 13,774 (256)

LRRK2 as a Potential Disease‐Modifying Target in Sporadic Parkinson's Disease

Movement Disorders, EarlyView.
Abstract A growing understanding of the role that leucine‐rich repeat kinase 2 (LRRK2) plays in Parkinson's disease (PD) supports continued focus on this enzyme as a therapeutic target for PD. Accumulating evidence suggests that there are phenotypic, neuropathologic, and biological similarities between sporadic PD (sPD) and familial forms in which ...
Anthony E. Lang, Robert A. Hauser, Lorraine V. Kalia, Bonnie Hersh, Zdenek Berger, Roy Llorens Arenas, Coro Paisan‐Ruiz, Kyle Fraser, Danna Jennings, Jillian H. Kluss, Sarah Huntwork‐Rodriguez, Anastasia G. Henry, J. Timothy Greenamyre   +12 more
wiley   +1 more source

Are resin sealants effective to treat caries lesions in the outer 1/3 of dentin compared to composite resin restorations? Systematic review and meta-analysis. [PDF]

Jpn Dent Sci Rev
Ito LY, Avais LS, Pacheco EC, Wambier LM, de Paula AM, Hanzen TA, Reis A, Wambier DS, Chibinski ACR.   +8 more
europepmc   +1 more source

Respiratory Syncytial Virus (RSV): A Comprehensive Overview From Basic Biology to Clinical Prevention and Control

Medicinal Research Reviews, EarlyView.
ABSTRACT Respiratory syncytial virus (RSV) is a common virus that causes respiratory infections, posing a serious threat, particularly to infants, the elderly, and individuals with compromised immune systems. As the leading cause of lower respiratory tract infections (LRTIs) in infants, RSV is responsible for millions of cases worldwide each year.
Jie Shi, Xiya Huang, Chunjun Ye, Yishan Lu, Yanyan Liu, Yuquan Wei, Xiawei Wei   +6 more
wiley   +1 more source

Effects of Cement Shade, Cementation, and Thermocycling on the Color Parameters and the Final Color of the SLA-Printed Photopolymer Resins. [PDF]

Polymers (Basel)
Kaynak Öztürk E, Yılmaz Biçer E, Güney B, Saygılı S, Aktaş N, Bankoğlu Güngör M.   +5 more
europepmc   +1 more source

Back to the Mission. Revisiting Slack in Nonprofits and Introducing Tappable Slack

Nonprofit Management and Leadership, EarlyView.
ABSTRACT This article contributes to and develops the previous literature on excess resources (“slack”) in nonprofit organizations through a conceptual analysis of the implications that the organizational distinctiveness of nonprofits carries for our understanding of slack in these organizations.
Marta Reuter, Ebba Henrekson, Filip Wijkström   +2 more
wiley   +1 more source

Efficacy of different cavity liners compared to no cavity lining in managing deep caries in vital permanent teeth - a systematic review. [PDF]

Clin Oral Investig
Kosan E, Kosan D, Sturm R, Schwendicke F, Paris S.   +4 more
europepmc   +1 more source

Migrasomes, Matrix‐Bound Nanovesicles, and More: Messengers in the Matrix

PROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) and particles (EPs) are diverse micro‐ and nanoparticles that circulate in bodily fluids and can attach to, or be deposited onto, the extracellular matrix (ECM) and other surfaces. To date, the nomenclature and classification of matrix‐bound or matrix‐associated EVs and EPs (MEVPs) have been unclear, largely due to
Anna V. Kolesov, Natalie Reitz, Marley Dewey, Colin L. Hisey   +3 more
wiley   +1 more source

Repair bond strength of composite resin to additively manufactured permanent resin materials: a comparative evaluation of light-cure, self-cure, and dual-cure universal adhesives. [PDF]

BMC Oral Health
Yildirim-Manav E, Yazici-Akbiyik S, Yikici-Çöl C.   +2 more
europepmc   +1 more source

Biomarker‐based long‐term safety and efficacy of PD‐1/PD‐L1 inhibitors combined with chemotherapy in advanced gastroesophageal carcinomas: A systematic review and meta‐analysis

Precision Medical Sciences, EarlyView.
This graphical abstract concisely encapsulates the principal findings of the meta‐analysis, emphasizing the notable survival advantages of PD‐1/PD‐L1 inhibitors in conjunction with chemotherapy for advanced gastroesophageal tumors. The visual presentation briefly defines the study's history, methodologies, results, and conclusions, while highlighting ...
Muhammad Ahsan, Muhammad Javaid Umer, Rath Shree, Jan Qureshi Ahmar, Ahmad Khan Mudassir, Masood Salman, Muhammad Hassan, Hayyat Omna, Iqbal Javed, Asraf Hussain   +9 more
wiley   +1 more source

Comparative Assessment of Microleakage in Nanoformulated and Conventional Glass Ionomer Cement under Simulated Aging: A Stereomicroscopic Study. [PDF]

Int J Clin Pediatr Dent
Alex A, Paulraj J, Pretty TN, Maiti S.
europepmc   +1 more source