CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 583-595, March 2025.ABSTRACT Prior pharmacokinetic (PK) analysis revealed that increased alpha‐1‐acid glycoprotein (AAG) levels are associated with decreased imatinib unbound fraction in coronavirus disease 2019 (COVID‐19) patients. This study aimed to investigate the PK of total and unbound concentrations of imatinib and the metabolite N‐desmethyl imatinib in ...
Medhat M. Said +10 more
wiley +1 more source
Efficacy of concentrated growth factor compared with other types of regenerative endodontic procedures: a systematic review. [PDF]
BMC Oral HealthAlmutairi M, Almotairy N, Alotaibi B.
europepmc +1 more source
Secretome Profiling in Axon Regeneration: Emerging Techniques and Therapeutic Translation
Sensory Neuroscience, EarlyView.ABSTRACT The secretome refers to the in vivo ensemble of molecular entities that are found in interstitial spaces. It is then the mere secreted products of the cells, as all biomolecules in the interstitial cellular spaces also undergo modifications. The fractionated secretome may hold potential as a cell‐free therapy option due to its role in tissue ...
Maria D. Cabrera +3 more
wiley +1 more source
Treatment of Horizontal Root Fractures in Traumatized Maxillary Central Incisors Using Minimally Invasive Surgical and Prosthodontic Foundation Techniques. [PDF]
Case Rep DentAtsumi K, Tanoue N.
europepmc +1 more source
Stabilized Extracellular Vesicle Formulations for Inhalable Dry Powder Development
Small, EarlyView.Extracellular vesicles (EVs) hold promise for chronic obstructive pulmonary disease (COPD) treatment but face challenges with storage and delivery. This study demonstrates the stabilization of lung fibroblast‐derived EVs using inulin, enabling freeze‐drying and spray‐drying.
Eva M. Jansen +7 more
wiley +1 more source
Treatments of dentition with four dens evaginatus and reverse overbite: a case report with a 6-year follow-up. [PDF]
BMC Oral HealthLuan M, Wang Q, Fang Y, Wang X.
europepmc +1 more source
Orchard Park, Town of and Orchard Park Employee Unit No. 6765-01, CSEA Local 1000, AFSCME, AFL-CIO, Erie County Local 815 (1999) (MOA) [PDF]
, 1999 core +1 more source
Small, Volume 21, Issue 29, July 24, 2025.This review presents a detailed overview of clinically approved nanoparticle therapeutics, classifying them by type and discussing their unique advantages in drug delivery. It highlights regulatory challenges across global markets and emphasizes the need for adaptive approval pathways.
Nimeet Desai +5 more
wiley +1 more source
Knowledge, attitudes, and practices among Syrian dentists towards minimal invasive dentistry and chemomechanical caries removal: a cross-sectional study. [PDF]
BDJ OpenAlakkad D +3 more
europepmc +1 more source
Augmented 3D Printing for Multiscale Microphysiological Systems
Small, EarlyView.This review explores augmented 3D printing techniques combined with multiscale ancillary methods to overcome current limitations in fabricating complex microphysiological systems (MPS). It covers 3D printing and ancillary techniques, and highlights advancements in augmented MPS that surpass conventional systems, offering more physiologically relevant ...
Kyeong Seob Hwang +7 more
wiley +1 more source