Results 91 to 100 of about 50,734 (274)

Epigenetic Dysregulation of the NKX2‐1/SPDEF Axis Drives Persistent Goblet Cell Differentiation and Epithelial Barrier Dysfunction in Chronic Obstructive Pulmonary Disease

Respirology, EarlyView.
This study investigated airway epithelial barrier dysfunction persistence in ex‐smokers with COPD and underlying mechanisms using single‐cell RNA and ATAC sequencing. Epigenetic NKX2‐1/SPDEF dysregulation maintains goblet cell hyperplasia and barrier dysfunction despite long‐term smoking cessation.
Ayaka Shiota, Keiko Kan‐o, Yumiko Ishii, Tomoaki Koga, Takeshi Sawada, Kei‐ichiro Yasunaga, Shingo Usuki, Tatsuya Katsuno, Shigesato Inoue, Tomohiro Ogawa, Akihiro Jo, Satoru Fukuyama, Mitsuyoshi Nakao, Hiroaki Ogata, Mizuho A. Kido, Sachiko Tsukita, Koichiro Matsumoto, Isamu Okamoto   +17 more
wiley   +1 more source

Techniques for fabrication of temporary dental restorations

, 2019
Introduction: Temporary restorations are an important part of modern prosthodontic treatment. Temporaries are made nearly exactly like the final restoration while protecting from mechanical, thermal, chemical and biological irritations and improving the patient esthetics and function. They are beneficial in diagnostics and treatment planning.
Zarkova, Julija, Dimitar, Mitev, Cvetanovski, Ognen   +2 more
openaire   +1 more source

Harnessing energy metabolism for enhanced bone defect repair: Mechanisms and therapeutic strategies

VIEW, EarlyView.
This review addresses the critical challenge of bone defect repair by focusing on the underexplored role of cellular energy metabolism. It synthesizes regulatory mechanisms in bone‐forming cells and sums up innovative strategies—leveraging cell derivatives, active factors, and biomimetic scaffolds—to modulate metabolism for enhanced regeneration.
Junting Li, Yulan Liu, Yuran Li, Yingjie Hua, Xinquan Jiang, Mingliang Zhou   +5 more
wiley   +1 more source

Contemporary Digital Treatment Of Resorbed Avulsed Maxillary Incisors: Multidisciplinary Approach

International Dental Journal
Introduction: Traumatic dental injuries, particularly avulsion of maxillary incisors, present significant clinical challenges. Long-term prognosis is often compromised by complications such as root resorption, requiring a strategic and multidisciplinary ...
Marjan Petkov, Julija Zarkova Atanasova, Vesna Trpevska, Daniela Veleska Stefkovska, Mihael Stanojevic, Marina Eftimovska, Vera Radojkova Nikolovska, Bruno Nikolovski, Vesna Jurukovska Shotarovska, Aneta Mijoska   +9 more
doaj   +1 more source

Effect of Intracanal Medications on the Viability of Human Periodontal Ligament‐Derived Mesenchymal Stem Cells

Australian Endodontic Journal, EarlyView.
ABSTRACT This in vitro study evaluated the effects of intracanal medications on the metabolic activity and adhesion of human periodontal ligament‐derived mesenchymal stem cells. Tested groups included Control (without medication), Triple Antibiotic Paste (TAP), Double Antibiotic Paste (DAP), calcium hydroxide with saline, calcium hydroxide with 2 ...
Arian Braido, Walbert de Andrade Vieira, Bruno Cazotti Pereira, Karina Gonzales Silvério, Paulo Henrique Gabriel, Aline Cristine Gomes Matta, Emerson Alves Martins, Adriana de Jesus Soares   +7 more
wiley   +1 more source

Molar incisor hypomineralisation: current knowledge and practice

International Dental Journal, EarlyView., 2020
Background Molar incisor hypomineralisation (MIH) is a common developmental dental condition that presents in childhood. Areas of poorly formed enamel affect one or more first permanent molars and can cause opacities on the anterior teeth. MIH presents a variety of challenges for the dental team as well as functional and social impacts for affected ...
Helen D. Rodd, Anna Graham, Niecoo Tajmehr, Laura Timms, Noren Hasmun   +4 more
wiley   +1 more source

Redesign of a fixture mount to be used as an impression coping and a provisional abutment as well

Contemporary Clinical Dentistry, 2011
Purpose: An integrated fixture mount/impression coping/ temporary abutment can provide many advantages for immediate loading of dental implants, such as simpler procedure, less chair time, cost reduction, and comfort for the patients.
Glenn Hsuan-Chen Chang, Chen Tian, Yuen-Siang Hung   +2 more
doaj   +1 more source

The Therapeutic Potential of Farm Dust Extracts in a Mouse Model of Eosinophilic Inflammation

Allergy, EarlyView.
Farm dust extract (FDE) treatment reduces airway eosinophilia, mucus overproduction, and MHC‐II expression on DCs, limiting antigen presentation and Th2 inflammation. It increases PD‐L1 on DCs, promoting T cell deactivation. Additionally, FDE enhances Tregs and upregulates CTLA‐4, reinforcing suppression.
Rabia Ülkü Korkmaz, Jimmy Omony, Xiaomei Tan, Markus Klotz, Guilherme Dragunas, Sirui Chen, Soni Shankhwar, Zeynep Ertüz, Christoph Müller, Mohab Ragab, Aicha Jeridi, Romina Augustin, Janna Nawroth, Theodore S. Kapellos, Bettina Rankl, Ali Önder Yildirim, Erika von Mutius   +16 more
wiley   +1 more source

Comparative Evaluation of Mechanical Properties and Color Stability of Dental Resin Composites for Chairside Provisional Restorations

Polymers
Resin composites have become the preferred choice for chairside provisional dental restorations. However, these materials may undergo discoloration, changes in surface roughness, and mechanical properties with aging in the oral cavity, compromising the ...
Haikun Yu, Jiaqi Yao, Zhili Du, Jingmei Guo, W. Lei   +4 more
semanticscholar   +1 more source

Model‐Based Cost‐Effectiveness of Direct Restorations: Amalgam Dominates

Community Dentistry and Oral Epidemiology, EarlyView.
ABSTRACT Objectives A phase‐down of dental amalgam use has been mandated and the feasibility of its phase‐out in England by 2030 is being explored. Amalgam use in English National Health Service (NHS) care still predominates for posterior restorations, though access to this care is increasingly limited.
O. Bailey, S. J. Stone, G. Taylor, L. Ternent, C. R. Vernazza   +4 more
wiley   +1 more source