Results 141 to 150 of about 148,753 (292)
Advanced Science, EarlyView.Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng +9 more
wiley +1 more source
Toxicity of Flow Line, Durafill VS, and Dycal to Dental Pulp Cells: Effects of Growth Factors [PDF]
, 2010 Introduction The objective was to determine the effects of growth factor treatment on dental pulp cell sensitivity to toxicity of 2 composite restoration materials, Flow Line and Durafill VS, and a calcium hydroxide pulp capping material, Dycal ...
Furey, Alyssa +2 more
core +1 more source
Advanced Science, EarlyView.Depression, a prevalent neuropsychiatric disorder with unclear pathogenesis, involves dysfunctional adenylyl cyclase 8 (Adcy8) as a key risk factor. Chronic stress selectively reduces Adcy8 expression in the dorsal CA1 (dCA1) neurons. Depletion of Adcy8 in dCA1 excitatory neurons induces depressive‐like behaviors by impairing neuronal excitability and ...
Zi‐Jie Liu +14 more
wiley +1 more source
Kouqiang hemian waike zazhi[Objective:] To explore the expression of cyclin-dependent kinase inhibitor 1A (CDKN1A/p21) in the healing process of tooth extraction wounds in diabetic mice and the effect on migration and polarization of macrophages.
ZHU Jiayu +5 more
doaj +1 more source
Advanced Science, EarlyView.By integrating a convergent molecular platform strategy, this study designed a novel dual‐target C5 to combat multidrug‐resistant Gram‐negative bacteria. C5 synergistically enhances antibiotic efficacy by inhibiting efflux pumps and increasing bacterial membrane permeability.
Jiale Dong +11 more
wiley +1 more source
Advanced Science, EarlyView.Merging 4D printing with magneto‐responsive shape memory polymers opens new avenues for intelligent, reconfigurable systems. This review navigates cutting‐edge fabrication techniques, magnetic fillers, and smart polymer matrices, unveiling their potential in soft robotics, biomedical devices, and wearable tech.
Kiandokht Mirasadi +7 more
wiley +1 more source
Spatial and temporal distribution of p21 senescent cells in periodontal tissue of diabetic mice
Kouqiang hemian waike zazhi[Objective:] To investigate the spatial and temporal distribution of p21 senescent cells in periodontal tissue and femur of diabetic mice. [Methods:] We constructed transgenic mice capable of tracing p21 senescent cells, used gel electrophoresis assay to
YI Zimei +5 more
doaj +1 more source