Results 141 to 150 of about 63,768 (313)

Mastication‐Induced Electrical Stimulation Activates Prg4+ Chondroprogenitors for Osteoarthritis Therapy

open access: yesAdvanced Science, EarlyView.
This study presents a ″trash‐to‐treasure″ strategy that converts harmful joint overloads into beneficial electrical cues. The biodegradable MagPie, by providing piezoelectrical stimulation and releasing Mg2+ during mastication, exerts synergistic pro‐regenerative and anti‐inflammatory effects on Prg4+ cells via the ECM‐mediated FAK‐PI3K‐Akt axis ...
Shi‐Yang Feng   +10 more
wiley   +1 more source

Lacc1-engineered extracellular vesicles reprogram mitochondrial metabolism to alleviate inflammation and cartilage degeneration in TMJ osteoarthritis

open access: yesJournal of Nanobiotechnology
Temporomandibular joint osteoarthritis (TMJOA) is a multifaceted degenerative disease characterized by progressive cartilage degradation, chronic pain, and functional limitations of the TMJ, significantly affecting patients’ quality of life.
Xiaofeng Hu, Jian Xie, Jiansheng Su
doaj   +1 more source

Effects of dental materials on insulin release from isolated islets of Langerhans

open access: yes, 2002
Objectives: To investigate the possibility of using a whole organ model for evaluating the biological effects of dental restoration materials in vitro. Methods: The effect on insulin release of isolated Langerhans islets of a series of dental materials ...
Sjögren, Göran,   +1 more
core   +1 more source

Quantum Photothermal Self‐Monitoring Fiber Probes for In Vivo Photothermal Therapy

open access: yesAdvanced Science, EarlyView.
A miniaturized quantum photothermal fiber probe based on a metal/polymer/glass composite optoelectronic fiber that simultaneously guides lightwave and microwave was developed for the first time. The probe achieves enhanced photothermal conversion (13°C/mW, 25°C–120°C range) while providing real‐time self‐monitoring with 0.2°C thermal resolution at the ...
Wanjun Li   +12 more
wiley   +1 more source

The Effect of Dental Implant Restoration on the Biomechanics of the Temporomandibular Joint in Patients with Posterior Tooth Loss: A Pilot Study

open access: yesBioengineering
Currently, controversy persists over whether dental implant restoration exacerbates or alleviates temporomandibular disorders (TMDs). This study aimed to analyze the impact of dental implant restoration on the biomechanics of the temporomandibular joint (
Yuanli Zhang   +8 more
doaj   +1 more source

Cytotoxicity and terminal differentiation of human oral keratinocyte by indium ions from a silver-palladium-gold-indium dental alloy

open access: yes, 2015
OBJECTIVE: Dental alloys containing indium (In) have been used in dental restoration for two decades; however, no study has investigated the biological effects of In ions, which may be released in the oral cavity, on human oral keratinocytes.
이정환   +4 more
core   +1 more source

SIRT6‐Mediated Deacetylation of ATF3 Promotes Silica‐Induced Lung Fibrosis by Enhancing its Nuclear Import via Binding to Importin α

open access: yesAdvanced Science, EarlyView.
SIRT6‐mediated ATF3 acetylation drives MGARP transcription and mitochondrial dysfunction in macrophages, promoting macrophage senescence and pulmonary fibrosis. Mechanistically, HSP70/Importin α competitively binds to ATF3, modulating its nuclear translocation.
Demin Cheng   +18 more
wiley   +1 more source

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