Results 41 to 50 of about 53,773 (266)

Dynamic Mechanical Loading Modulates Extracellular Vesicle Production and Cargo in Meniscus Fibrochondrocytes

Advanced Materials Interfaces, EarlyView.
Dynamic mechanical loading of outer meniscus fibrochondrocytes increases extracellular vesicle (EV) yield and alters EV composition. When applied to progenitor cells, these mechanically primed EVs modulate the expression of matrix‐related genes.
Catherine Cheung, Zizhao Li, Sung‐Han Jo, Se‐Hwan Lee, Il Keun Kwon, Jina Ko, Su Chin Heo   +6 more
wiley   +1 more source

Perivascular Matrix Densification Dysregulates Angiogenesis and Activates Pro‐Inflammatory Endothelial Cells

Advanced Science, EarlyView.
Perivascular matrix densification promotes the emergence of aberrant endothelial tip cells (ATECs) that invade and persist within fibrotic microenvironments. Using in vivo lineage tracing and a human microvessel model, this study shows that fibrous matrix cues destabilize VE‐cadherin–mediated junctions to gate TGF‐β signaling, inducing a pro ...
Jingyi Xia, William Y. Wang, Kyle A. Jacobs, Kairav Maniar, Daphne Lin, Evan H. Jarman, Daniel L. Matera, Kristen Loesel, Christopher D. Davidson, Harrison L. Hiraki, Xiaotian Tan, Eve H. Shikanov, Robert N. Kent, Carole Parent, Xudong Fan, Ariella Shikanov, Matthew L. Kutys, Brendon M. Baker   +17 more
wiley   +1 more source

Assessment of the efficacy of autologous blood preparations in maxillary sinus floor elevation surgery: a systematic review and meta-analysis

BMC Oral Health
Objective This study aimed to evaluate the efficacy of autologous blood preparations, namely Platelet-Rich Plasma (PRP), Platelet-Rich Fibrin (PRF), and Concentrated Growth Factor (CGF), in maxillary sinus floor elevation surgery.
Piaopiao Qiu, Xuehan Zhang, Rongkai Cao, Hui Xu, Zihan Jiang, Jingshi Lei   +5 more
doaj   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Low-intensity pulsed ultrasound ameliorates partial infraorbital nerve ligation-induced trigeminal neuropathic pain through inhibiting Schwann cell Pannexin 1 channel

Frontiers in Immunology
BackgroundNeuroinflammation significantly contributes to trigeminal neuropathic pain (TNP). Low-intensity pulsed ultrasound (LIPUS) showed anti-inflammatory function in several diseases.
Yao Liu, Xue Han, Weijie Zhang, Qingguo Pei, Shuyu Xu, Haicheng Wang   +5 more
doaj   +1 more source

Cigarette Smoke‐Induced Alveolar Macrophage Senescence via GEM/SIRT3‐Mediated Mitochondrial Dysfunction

Advanced Science, EarlyView.
Cigarette smoke accelerates the aging of immune cells in the lung. By combining human single‐cell sequencing, cell culture, and mouse models, the authors show that the protein GEM drives mitochondrial damage and senescence in alveolar macrophages by suppressing SIRT3.
Jin Wang, Meidan Wei, Xiangrong Song, Jiaxin Zhang, Lisha Zhang, Sixian Chen, Yaoyu Hu, Hui Gao, Jianxiang Li   +8 more
wiley   +1 more source

Oral Motion‐Powered Smart Dental Implant Abutment for In Situ Antibacterial and Cell Adhesion Through Piezoelectric Effect

Advanced Science, EarlyView.
We proposed a method based on the piezoelectric effect and fabricated an implant abutment on the basis of piezoelectric ceramic. Under physiological occlusal pressure, the oral motion‐powered smart dental implant abutments interacted with water and oxygen, promoting the formation of reactive oxygen species and achieving a synergistic and highly ...
Xiyu Shi, Xiaoyu Han, Yanhui Lu, Yuan Chai, Baiyan Xiao, Shuo Liu, Boon Chin Heng, Tingting Wu, Tingjun Li, Qiaomei Ren, Ting Song, Le Chen, Dong Han, Yaru Guo, Xuliang Deng, Xuehui Zhang   +15 more
wiley   +1 more source

Comparison of Marginal Integrity  of Class-1 Restorations With Spectrum Tph-3 Versus Nexcomp In Mandibular Molars - A Quasi-Experimental Study

Pakistan Armed Forces Medical Journal
Objective: To compare the marginal integrity of Class-1 restorations with Spectrum TPH-3 vs Nexcomp in mandibular molars. Study Design: Quasi-experimental study.
Nasir Jamal Baig, Fahmeed Akhtar, Muzzamil Jamil Ahmad Rana, Mafaza Alam, Mehmood Ahmad Rana, Mehvish Abbas   +5 more
doaj   +1 more source

Non-Metallic Biomaterials for Tooth Repair and Replacement. By Pekka Vallittu, Woodhead Publishing, 2013; 406 pages. Price £145.00/US$245.00/€175.00 ISBN 978-0-85709-244-1

Journal of Functional Biomaterials, 2013
1. Discusses the properties of enamel and dentin and their role in adhesive dental restoration;2. Chapters also examine the wear properties of dental ceramics, glasses and bioactive glass ceramics for tooth repair and replacement;3. Dental composites and
Shu-Kun Lin
doaj   +1 more source

A Fentanyl‐Responsive Microneedle Patch for Harm Reduction

Advanced Science, EarlyView.
A fentanyl‐responsive microneedle patch is developed as a self‐regulating overdose intervention that releases naloxone upon detecting fentanyl. The system employs aptamer‐functionalized nanoparticles embedded in a swellable polymer matrix to enable rapid, on‐demand drug delivery through the skin.
Penghui Zhao, Zerui Zhou, Tyler Wolter, Huanqing Niu, Yuanzhi Bian, Chixia Tian, Chun Xu, Chenming Zhang, Juhong Chen, Matthew W. Buczynski, Wujin Sun   +10 more
wiley   +1 more source