Results 121 to 130 of about 73,214 (250)

Retention failures in cement- and screw-retained fixed restorations on dental implants in partially edentulous arches: A systematic review with meta-analysis

open access: yesThe Journal of Indian Prosthodontic Society, 2018
This systematic review aimed to evaluate retention failures in cement- and screw-retained fixed restorations on dental implants in partially edentulous arches.The relevant articles were retrieved from MEDLINE (PubMed), Cochrane Library, and EBSCO electronic databases for articles published from January 1995 to January 2016 and were restricted to ...
Jatin K Jain   +6 more
openaire   +3 more sources

Hepatocyte BDNF Acts as a Novel Immune Checkpoint to Restrain TLR4‐Mediated Acute Hepatitis

open access: yesAdvanced Science, EarlyView.
This study identifies hepatocyte‐derived BDNF as an endogenous TLR4 antagonist that alleviates acute hepatitis. BDNF is downregulated in hepatocytes via REST‐mediated transcriptional repression during ALI/ALF. Mechanistically, BDNF binds to TLR4 on macrophages to suppress inflammation.
Weiwei Zhu   +15 more
wiley   +1 more source

Visualization of interfacial adhesive defects at dental restorations with spectral domain and polarization sensitive optical coherence tomography

open access: yesCurrent Directions in Biomedical Engineering, 2018
Restoration loss based on interfacial adhesive defects and associated caries at the restoration margin are the main causes for invasive replacement of dental restorations.
Tetschke Florian   +8 more
doaj   +1 more source

Development‐based In Vivo Bioreactor Strategy for Challenging Senescent Bone Reconstruction

open access: yesAdvanced Science, EarlyView.
We present a development‐based in vivo bioreactor strategy to generate rejuvenated bone grafts (vBR‐Bone) within aged hosts. By enclosing vBR‐Bone fragments within an asymmetric biomimetic periosteum, segmental femoral defects in aged mice were successfully repaired within 6 weeks. Mechanistically, the multifactors of vBR‐Bone reconstitute a remodeling
Wenchao Zhang   +9 more
wiley   +1 more source

Seal capability of interim post and core crown with temporary cements

open access: yesBrazilian Oral Research, 2010
The purpose of the present study was to evaluate the in vitro seal capability of interim post and core crown restorations. Eighty teeth were selected and divided into 8 groups. Four experimental groups received interim posts and core crowns. Half of each
Guilherme Bönecker-Valverde   +4 more
doaj   +1 more source

The causes of failure and the longevity of direct coronal restorations: A survey among dental surgeons of the town of Abidjan, Côte d'Ivoire

open access: yesJournal of Conservative Dentistry, 2019
This study aimed to itemize the causes for the failure of direct coronal restorations (DCRs) according to the practitioners of Côte d'Ivoire in order to provide recommendations for good practice.A descriptive, self-reporting, prospective survey was carried out among 109 dental surgeons (DSs) in the town of Abidjan based on 587 randomly selected ...
Avoaka-Boni, Marie-Chantal   +4 more
openaire   +3 more sources

ALKBH3 m1A Demethylase Deficiency Reduces Alzheimer's Amyloid‐β Pathology

open access: yesAdvanced Science, EarlyView.
This study identifies that ALKBH3‐driven m1A demethylation orchestrates Alzheimer's disease progression by disrupting mitochondrial and synaptic homeostasis. This epitranscriptomic mechanism suppresses PINK1‐mediated mitophagy via m1A erasure, leading to mitochondrial dysfunction, oxidative stress, elevated Aβ production, and impaired microglial ...
Yueyang Li   +25 more
wiley   +1 more source

Romanian dentists’ perception about direct restoration of dental caries on adjacent teeth: current techniques and materials, restorations longevity and failures. Part II

open access: yesRomanian Journal of Stomatology
Proximal surfaces of both anterior and posterior teeth frequently present dental caries, as a result of complex coronal morphology and other associated factors which favors bacterial microfilm retention. In this article we present the second part results of a cross-sectional study, using a questionnaire that was distributed to a number of 110 Romanian ...
Irina-Maria Gheorghiu   +3 more
openaire   +2 more sources

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

open access: yesAdvanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang   +6 more
wiley   +1 more source

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