Results 101 to 110 of about 5,533,800 (301)

restorative materials

open access: yes, 2021
Objective: Nanotechnology has progressed significantly and particles as small as 3 nm are being employed in resin-based restorative materials to improve clinical performance.
Sandro Basso Bitencourt   +7 more
core   +1 more source

PEAR1 Promotes Glucose Metabolism Reprogramming in Sepsis‐Associated Acute Lung Injury via AARS1‐Mediated HIF‐1α Lactylation

open access: yesAdvanced Science, EarlyView.
This study revealed that a PEAR1/HIF‐1α/ glycolysis/lactate/H3K18la positive feedback loop in PMVECs that drives the development of S‐ALI. Mechanistically, PEAR1 mediates the binding of HIF‐1α to AARS1, leading to the lactylation of HIF‐1α, the primary lactylation site of which is K172.
Shuai Li   +15 more
wiley   +1 more source

Evaluation of some mechanical and optical properties of modified glass ionomer cement with TiO2 and SiO2 nanoparticles

open access: yesBulletin of the National Research Centre
Background Glass ionomer cements with extended setting time and inferior mechanical properties present significant challenges for dentists in clinical practice. Thus, various alterations aimed to enhance their properties.
Mai M. Elbatanony, Amal M. El Shahawi
doaj   +1 more source

Enhancing Super‐Resolution Spatial Transcriptomics Data by Transfer Learning

open access: yesAdvanced Science, EarlyView.
SpotZoomer employs a transfer‐learning‐based strategy to enhance the resolution of Visium data by leveraging available high‐resolution priors. The resulting super‐resolved maps enable sharper delineation of cell boundaries and more precise inference of cell–cell communication patterns that would otherwise remain obscured at native resolution.
Xiaoyu Li, Lihua Zhang, Wenwen Min
wiley   +1 more source

Development of a novel Agarose/Nano-Hydroxyapatite/Grape seed extract hydrogel for biomimetic remineralization of demineralized human enamel (An In-Vitro Study)

open access: yesScientific Reports
Enamel prisms possess a unique microstructure, and their damage due to erosion is irreversible, making enamel restoration through non-invasive regeneration a significant challenge.
Hanaa M. Elgamily   +2 more
doaj   +1 more source

Neuropeptide Y—Graphene Oxide Complexes Inhibit Amygdala NPY‐Receptor Expressing Glutamatergic Pathways and Selectively Remove Aversive Memory In Vivo

open access: yesAdvanced Science, EarlyView.
A graphene oxide nanocarrier presents neuropeptide Y specifically to NPY receptor‐expressing pathways in the amygdala, whose activation selectively suppresses aversive memory formation, without modulating anxiety responses. This circuit‐restricted drug release strategy may impact future design of neuropsychiatric therapies with limited off‐target ...
Elisa Pati   +10 more
wiley   +1 more source

Lessening the erosive influence of electrolyte sports drinks on teeth using L-arginine and aqueous Miswak extract

open access: yesHead & Face Medicine
Objective Excessive intake of electrolyte sports drinks (ESDs) among adolescents and athletes is associated with dental erosion due to their low pH, while their sugar content increases the risk of dental caries.
Hanaa Elgamily   +4 more
doaj   +1 more source

Embryotoxicity of dental restorative materials [PDF]

open access: yesActa stomatologica Croatica, 2020
Introduction: Final adjustment and polishing or removal of dental fillings produce particles of restorative materials of various sizes that can reach the wastewater. The purpose of this study is to investigate the effect of particles of restorative materials and their degradation products on the environment and non-target organisms using Danio rerio ...
Tarle, Zrinka   +4 more
openaire  

QRICH1 Disrupts Endoplasmic Reticulum Homeostasis and Amplifies NF‐κB Signaling in Periodontal Ligament Stem Cells to Exacerbate Diabetic Periodontitis

open access: yesAdvanced Science, EarlyView.
QRICH1 has been established as a key factor contributing to impaired osteogenic potential and accelerated apoptosis of PDLSCs in diabetic periodontitis. QRICH1 not only significantly enhances UPR‐associated apoptotic signaling but also amplifies NF‐κB‐mediated inflammatory responses. Its inhibition restores osteogenic capacity and reduces alveolar bone
Han Li   +9 more
wiley   +1 more source

Renal Clearable Luminogenic Reporter for Ultrasensitive Influenza Virus Imaging and Efficient Antiviral Therapies Monitoring in Living Mice

open access: yesAdvanced Science, EarlyView.
A viral luminogenic reporter with chemiluminescence/fluorescence dual‐response and efficient renal clearance was developed for non‐invasive imaging and urinalysis of H1N1 virus protease, allowing for remote detection of H1N1 virus infections and monitoring of antiviral therapeutic efficacy in living mice.
Bankang Ruan   +9 more
wiley   +1 more source

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