Results 151 to 160 of about 107,681 (307)

Dying to work? An investigation into work-related stress, quitting intentions and absenteeism [PDF]

open access: yes
The paper uses data from the International Social Surveys Program (ISSP) to investigate work-related stress among a group of 15 OECD countries. It examines the determinants of work-related stress and explores the importance of work-related stress as a ...
Melanie E. Ward, Leontaridi, Rannia M.
core  

Prevalência de Úlceras Aftosas Recorrentes e nível de estresse percebido em alunos do curso de graduação em odontologia da Universidade Federal de Santa Catarina [PDF]

open access: yes, 2015
TCC (graduação) - Universidade Federal de Santa Catarina. Centro de Ciências da Saúde. Odontologia.A Úlcera Aftosa Recorrente (UAR) é uma das desordens mais comuns da cavidade oral. Sua etiologia ainda permanece desconhecida.
Michels, Júlia
core  

Hyperlipidemia Aggravates Alveolar Bone Loss via Periodontal Ligament Stem Cell Ferroptosis Through GSK3β Dependent Ubiquitin‐Mediated NRF2 Degradation

open access: yesAdvanced Science, EarlyView.
Lipid metabolic stress triggers ferroptosis in PDLSCs through the GSK3β/NRF2 pathway, thereby aggravating periodontal bone loss. Upregulated GSK3β promotes NRF2 ubiquitination and proteasomal degradation via β‐TrCP, suppressing NRF2 nuclear translocation and antioxidant target expression.
Yuxiao Zhang   +11 more
wiley   +1 more source

Analysis of the main stresses on dental crowns

open access: yes, 2020
Corneliu Drugă   +3 more
openaire   +1 more source

On the mechanical behaviour of human tooth structures: An application of the finite element method of stress analysis

open access: yes, 1975
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The Finite Element Method of stress analysis is employed in axisymmetric, two and three-dimensional forms, to investigate the mechanical behaviour of dental
Wright, KWJ
core  

Influence of post design and elastic modulus mismatch between dentin and post-core on stress distribution in endodontically treated teeth: a finite element analysis study

open access: yes
Background: ParaPost Fiber Posts are made to use resin-based cement and core build-up materials to provide an optimal Monoblock between the dentin-post-crown, resulting in one cohesive restoration.
Yalamanchi, Anusha   +5 more
core   +1 more source

A Biomimetic Nanoparticle System Intercepts and Degrades Thrombospondin‐1 to Restore Vascular Homeostasis After Ischemic Injury

open access: yesAdvanced Science, EarlyView.
TAX2‐NPs capture extracellular TSP‐1 in the injured liver and promote its macrophage‐mediated autophagic degradation. This process blocks TSP‐1/CD47 signaling, restores VEGFR2‐AKT activity, preserves endothelial function, and mitigates hepatic ischemia‐reperfusion injury.
Haorui Wang   +12 more
wiley   +1 more source

Boosting Sensory Nerve‐to‐Bone Interactions Enhances Hedgehog Mediated Calvarial Bone Repair

open access: yesAdvanced Science, EarlyView.
Boosting sensory nerve activity via TrkA agonism strongly accelerates calvarial bone repair in adult mice. Furthermore, single‐cell RNA sequencing and neuron–bone interactome analyses identify these sensory neurons as a direct neural source of Hedgehog pathway ligands. Consequently, these ligands drive osteoblast differentiation of skeletal progenitors,
Zhao Li   +9 more
wiley   +1 more source

Caveolin‐1 Stabilizes SERCA2 to Counteract Acute Kidney Injury via Suppression of Ca2+‐Dependent Endoplasmic Reticulum Stress in Distal Tubules

open access: yesAdvanced Science, EarlyView.
In AKI, initial kidney injury upregulates the expression of Cav‐1, which subsequently binds to and stabilizes SERCA2 via its scaffolding domain and through deubiquitination, thereby regulating Ca2+ homeostasis and ER stress. Conversely, Cav‐1 deficiency accelerates SERCA2 degradation, triggering Ca2+ overload and ER stress, and ultimately exacerbating ...
Yan Zhang   +19 more
wiley   +1 more source

WTAP‐Mediated m6A Modification Targets the LRP1‐Lipid Metabolism Axis to Regulate Joint Cartilage Regeneration

open access: yesAdvanced Science, EarlyView.
WTAP drives cartilage regeneration by activating an LRP1‐dependent lipid metabolic program in macrophages, enhancing IL‐10 and TGF‐β secretion to promote chondrogenic differentiation. Leveraging this mechanism, virtual screening identifies LRP1‐targeting compounds that effectively stimulate cartilage repair, highlighting a druggable epigenetic ...
Chenyan Huang   +6 more
wiley   +1 more source

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