Results 31 to 40 of about 77,724 (314)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

DENTAL ANXIETY AMONG DENTAL STUDENTS [PDF]

open access: yesJournal of IMAB - Annual Proceeding (Scientific Papers), 2011
Dental anxiety and dental fear are major factors causing much troubles for the people attending to their own personal health. Statistics show that the 25-26-year-olds experience higher dental anxiety than others. This can be accounted for by the diverse, intense effects of a number of psychological factors in this age range that can cause dental fear ...
openaire   +2 more sources

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Knowledge, attitude and practice of dentists toward providing care to the geriatric patients

open access: yesBMC Geriatrics, 2021
Background Tooth loss, systemic diseases and medications add to the complexity of the oral conditions in geriatric popuation, making this age group a special group in need of specific preventive and curative oral health care.
Bahareh Tahani   +1 more
doaj   +1 more source

Training Dental Students in Dental Amalgam Condensation

open access: yesThe Journal of Nihon University School of Dentistry, 1977
In studying the characteristics of dental amalgam condensation by 36 dental students, it is concluded that : (1) A minimum force of 800 1 b/inch2 is required per condensation stroke in order for the condensation stroke to have any effect on the slow compressive strength test values as a predictor of marginal fracture.(2) A 30, 000 1 b/inch2 slow ...
G, Salvendy   +4 more
openaire   +3 more sources

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

open access: yesFEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima   +4 more
wiley   +1 more source

Optimizing the Synthesis of Novel Calcium Carbonate/Cobalt Oxide Nanocomposite With Highest Antifungal Activity

open access: yesAdvances in Materials Science and Engineering
Today, the rise of opportunistic infections and their resistance to current antifungal drugs has led to the inevitable need to produce effective antimicrobials at a reasonable cost.
Nima Fallahnia   +3 more
doaj   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

open access: yesFEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori   +8 more
wiley   +1 more source

Comparative color stability assessment of orthodontic clear aligners: an in vitro study

open access: yesScientific Reports
Objective To evaluate the stain resistance and color stability of four Clear aligners (CA) brands against various beverages at different intervals, along with assessing the elaboration of cleaning agents. Methods In a strictly controlled lab environment,
Nancy Ajwa   +3 more
doaj   +1 more source

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