Results 51 to 60 of about 381,599 (340)

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Optimizing the Synthesis of Novel Calcium Carbonate/Cobalt Oxide Nanocomposite With Highest Antifungal Activity

Advances in Materials Science and Engineering
Today, the rise of opportunistic infections and their resistance to current antifungal drugs has led to the inevitable need to produce effective antimicrobials at a reasonable cost.
Nima Fallahnia, Mohammad Salmani Mobarakeh, Hasti Sarabikia, Mohsen Safaei   +3 more
doaj   +1 more source

Oral health beliefs and behaviors of nurse and nurse practitioner students using the HU-DBI inventory: An opportunity for oral health vicarious learning [PDF]

, 2017
Background: Oral health access to care issues are resulting in curricular changes to train nursing students as oral health educators and providers. However, little data are available concerning their personal oral health beliefs/behaviors.
Jackson, Richard D., Walker, Kimberly K.
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Comparative color stability assessment of orthodontic clear aligners: an in vitro study

Scientific Reports
Objective To evaluate the stain resistance and color stability of four Clear aligners (CA) brands against various beverages at different intervals, along with assessing the elaboration of cleaning agents. Methods In a strictly controlled lab environment,
Nancy Ajwa, Fatimah Radhi, Rana Aloraini, Ghadi AlSaydalani   +3 more
doaj   +1 more source

Career aspirations of dental students: insights from a multinational study using social cognitive career theory (SCCT)

Frontiers in Oral Health
BackgroundDental students' career choices are shaped by many factors, including their personal abilities and goals, environmental factors and the resources available to them.
Abanoub Riad, Abanoub Riad, Abanoub Riad, Lamis Elsheikh, Silvi Domnori, Silvi Domnori, Silvi Domnori, Aurora Doris Fratila, Aurora Doris Fratila, Charlotte Carter, Deniz Devrim Kaya, Deniz Devrim Kaya, Ekaterina Volevach, Rachael England, Mariana Morgado, Mariana Morgado, Julien Issa, Julien Issa, Sameh Attia, Mick Armstrong, Doniphan Hammer, Azamat Baigulakov, IADS Delegates, EDSA Delegates, Aya Abdelrahim, Yousif Alhasan, Selim Tunahan Akçay, Osman Çaksen, Ersid Domnori, Andrea Martinez, Gabriela Molina, Juan Fernando Morales, Aya Eida, Gamal ElGhonemy, Zeinab Hassan, Rawan Mahmoud, Eni Shaqiri, Zeynep Önen   +37 more
doaj   +1 more source

Use of Interdisciplinary Education to Foster Familiarization among Health Professionals [PDF]

, 1986
This paper describes a pilot interdisciplinary experience between the dental hygiene and medical technology programs at Marquette University. It was designed, in part, to familiarize dental hygiene students with the medical technology profession ...
Laatsch-Lybeck, Linda Jean, Milson, Linda, Zimmer, Susan E.   +2 more
core   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

CLASSIFICATION OF CHIEF-COMPLAINTS FOR PATIENTS REPORTING AT EMERGENCY DEPARTMENTS

Journal of University Medical & Dental College, 2015
: Timely disease detection in case of Infectious Diseases (IDs) can provide sufficient time for disease control activities that might help in controlling the spread of disease to a great extent. Generally, medical diagnostic procedures are time consuming
Muhammad Asif Ali, Shagufta Habib, Zahra Ahsan   +2 more
doaj   +2 more sources