Results 151 to 160 of about 3,553,040 (386)

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

open access: yesAdvanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang   +15 more
wiley   +1 more source

Single‐Field Evolution Rule Governs the Dynamics of Representational Drift in Mouse Hippocampal Dorsal CA1 Region

open access: yesAdvanced Science, EarlyView.
Long‐term hippocampal place‐code dynamics are investigated using calcium imaging across weeks of maze navigation. Analyses reveal a novelty‐irrelevant Single‐Field Evolution Rule (SFER), where active fields promote persistence and inactive fields decline.
Cong Chen   +10 more
wiley   +1 more source

A comparative study of patient satisfaction about anesthesia with dexmedetomidine for ambulatory dental surgery. [PDF]

open access: yesBMC Res Notes, 2022
Garip L   +5 more
europepmc   +1 more source

The Geometry of Layer 2/3 Cortical Sound Processing in Slow Wave Sleep

open access: yesAdvanced Science, EarlyView.
Sleep is associated with a sensory disconnection whose mechanisms remain elusive. Large neuronal population recordings in the auditory cortex revealed that, in NREM sleep, the neural code for sounds is highly similar to wakefulness, but coordinated modulations of neuron responsiveness intermittently disconnect the local cortical networks from sensory ...
Allan Muller   +3 more
wiley   +1 more source

Factors Responsible for the Performance of Final-Year Dental Surgery Students in Their Professional Examinations in Nigeria. [PDF]

open access: yesJ West Afr Coll Surg, 2023
Imediegwu KU   +7 more
europepmc   +1 more source

Outlook: Summer 2000 [PDF]

open access: yes, 2000
Alumni publication of the Boston University School of Dental ...
Office of External Affairs, Boston University Goldman School of Dental Medicine
core  

Cinnamic‐Hydroxamic‐Acid Derivatives Exhibit Antibiotic, Anti‐Biofilm, and Supercoiling Relaxation Properties by Targeting Bacterial Nucleoid‐Associated Protein HU

open access: yesAdvanced Science, EarlyView.
Cinnamic‐hydroxamic‐acid derivatives (CHADs) are identified as novel inhibitors of the bacterial nucleoid‐associated protein HU, exhibiting potent antibacterial, anti‐biofilm (both inhibition and eradication), and DNA relaxation (anti‐supercoiling) activities. Moreover, CHADs demonstrate strong synergistic effects with multiple antibiotics.
Huan Chen   +22 more
wiley   +1 more source

What Factors Affect Changes in Body Composition and Swallowing Function in Patients Hospitalized for Oral Cancer Surgery?

open access: yesClinical Interventions in Aging, 2020
Yuko Kagifuku,1 Haruka Tohara,1 Yoko Wakasugi,1 Chiaki Susa,1 Ayako Nakane,1 Mizue Toyoshima,2 Koichi Nakakuki,3 Yuji Kabasawa,4 Hiroyuki Harada,5 Shunsuke Minakuchi1 1Department of Gerontology and Gerodontology, Division of Gerodontology and Oral ...
Kagifuku Y   +9 more
doaj  

Home - About - Disclaimer - Privacy