Results 101 to 110 of about 623,950 (286)

Renal Clearable Luminogenic Reporter for Ultrasensitive Influenza Virus Imaging and Efficient Antiviral Therapies Monitoring in Living Mice

open access: yesAdvanced Science, EarlyView.
A viral luminogenic reporter with chemiluminescence/fluorescence dual‐response and efficient renal clearance was developed for non‐invasive imaging and urinalysis of H1N1 virus protease, allowing for remote detection of H1N1 virus infections and monitoring of antiviral therapeutic efficacy in living mice.
Bankang Ruan   +9 more
wiley   +1 more source

Caplan’s syndrome – rare pneumoconioses in clinical practice: case report

open access: yesMedycyna Pracy
Pneumoconioses are among the most frequently diagnosed occupational diseases in Poland, with collagenous pneumoconiosis forming a significant subgroup. These diseases develop as a result of exposure to fibrogenic dusts.
Monika Najder-Gawlik, Marta Wiszniewska
doaj   +1 more source

Technological aspects in manufacturing of aesthetic prosthetic restorations with metal infrastructure [PDF]

open access: yesRomanian Journal of Medical Practice
Restoring the morphology and functionality of dental arches affected by carious lesions and/or edentations using fixed prosthetic restorations has been a continuous challenge for dentists.
Andreea Angela STETIU   +9 more
doaj   +1 more source

Integrated Single‐Cell and TCR Profiling Reveals Protection‐Associated CD8+ T Cell Subsets Linked to Viral Control in PRRSV

open access: yesAdvanced Science, EarlyView.
PRRSV vaccine‐mediated protection is associated with clonally expanded cytotoxic CD8+ T cell subsets driven by viral structural proteins and supported by innate TLR4/TLR8 signaling and CD4+ T cell help, whereas non‐protective responses are characterized by dysfunctional exhausted‐like CD8+ T cells linked to poor viral control.
Can Kong   +14 more
wiley   +1 more source

Oral Health-Related Complications of Breast Cancer Treatment: Assessing Dental Hygienists’ Knowledge and Professional Practice

open access: yes, 2014
Purpose: Approximately 200,000 women are diagnosed with breast cancer in the U.S. every year. These patients commonly suffer from oral complications of their cancer therapy.
Inglehart, Marita Rohr   +2 more
core   +1 more source

Integrated Single‐Nucleus Multi‐Omics Atlases Reveal Lineage Plasticity and Regulatory Networks of Luminal Epithelial Cells During Mammary Gland Lactation and Involution

open access: yesAdvanced Science, EarlyView.
This study integrates single‐cell multi‐omics, spatial transcriptomics, and cross‐species comparative analyses to systematically characterize the cellular composition and differentiation trajectories of goat mammary epithelial cells, along with the gene regulatory networks and intercellular communication mechanisms governing these trajectories, thereby
Xiaoru Yan   +12 more
wiley   +1 more source

Adaptation of Echinococcus Multilocularis to Oxidative Stress Depends on EmPDK‐Mediated Metabolic Reprogramming

open access: yesAdvanced Science, EarlyView.
Metabolic adaption presents a vital survival strategy for E. multilocularis. This study identifies EmPDK as a central metabolic regulator governing glucose metabolic reprogramming. Oxidative stress activates EmHIF1α to induce EmPDK expression. Mechanistic characterization reveals this ROS/EmHIF1α/EmPDK axis drives glycolytic reprogramming to sustain ...
Huijuan Wang   +5 more
wiley   +1 more source

Matrix Stiffness Enhances Odontogenic Differentiation of DPSCs through Membrane Curvature Protein Baiap2‐Modulated Exosome Release

open access: yesAdvanced Science, EarlyView.
Matrix stiffness softening is identified as a previously underappreciated feature in deep caries. Higher stiffness drives exosome release in dental pulp stem cells through a coordinated mechanism involving PI3K–AKT‐regulated Baiap2 and kinesin‐1, thereby promoting odontogenic differentiation.
Bilun Jin   +10 more
wiley   +1 more source

Prosthodontic management of a patient with mandibular asymmetry: a case report

open access: yesClinical Case Reports, 2018
Key Clinical Message This case report outlines a conservative treatment approach utilized in the management of a patient with a transverse left‐sided mandibular asymmetry, in an attempt to obtain a functional and esthetic occlusion using removable ...
Nicola Holland, Gerald McKenna
doaj   +1 more source

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