An Implanted Tooth That Can Feel
Advanced Science, EarlyView.To endow the implanted tooth with masticatory perception, herein we demonstrate that a 3D‐printed piezoelectric‐core/robust‐sheath implanted tooth can rebuild the sensing feedback, serving as “mechanoreceptors” in converting the mechanical chewing force to electrical signals, and up to brain through surrounding alveolar nerve system.
Yaru Cao +13 more
wiley +1 more source
Tompkins, Seneca, and Tioga BOCES District and Clerical, Maintenance, Printing and Technical Services Employees, Tompkins-Seneca-Tioga BOCES Employees Association (2005) [PDF]
, 2005 core +1 more source
Biomimetic Cell Membrane‐Coated MOFs System for Targeted Cancer Therapy
Advanced Science, EarlyView.Biomimetic MOF‐based drug delivery nanoplatforms synthesized using liposomes or cell membranes as camouflage for multiple cancer therapeutics. ABSTRACT The integration of metal‐organic frameworks (MOFs) with cell membrane coatings has emerged as a revolutionary strategy to enhance the therapeutic efficacy of cancer nanomedicine.
Qilu Wu +6 more
wiley +1 more source
Broome-Delaware-Tioga Board of Cooperative Educational Services (BOCES) Sole Supervisory District and Board of Cooperative Educational Services (BOCES) Support Services Association (2003) [PDF]
, 2003 core +1 more source
Designing Scalable Mechano‐Virucidal Nanostructured Acrylic Surfaces for Enhanced Viral Inactivation
Advanced Science, EarlyView.Can a surface be designed to physically break viruses? This study explores how nanoscale geometry—specifically the spacing of tiny pillars—can determine whether viruses remain intact or rupture. Using flexible acrylic and a scalable fabrication process, the authors develop nanopillared, transparent surfaces that show strong antiviral activity without ...
Samson W. L. Mah +14 more
wiley +1 more source
Advanced Science, EarlyView.Sepsis‐associated acute kidney injury is driven by oxidative stress, NETs overproduction, and dysregulated innate immunity. Here, we develop neutrophil‐mimetic nanoscavengers that integrate ROS‐scavenging Mn3O4 nanozymes with DNase‐1‐mediated NETs degradation to suppress cGAS‐STING signaling, reprogram macrophage polarization, and effectively alleviate
Zening Zhang +9 more
wiley +1 more source
Board of Cooperative Educational Services, Broome-Tioga Counties and BOCES Support Services Association (2006) [PDF]
, 2006 core +1 more source
Integrating Human Intestinal Organoids into FDA'S New Approach Methodologies for Drug Discovery
Advanced Science, EarlyView.Illustration summarizes how human intestinal organoids (HIOs) are becoming transformative in preclinical research. Preclinical drug discovery pipelines often rely on animal models for ADMET studies, even though interspecies ADME gaps, poor external validity, and high attrition rates are common.
Debarun Patra +6 more
wiley +1 more source
Knowledge, attitudes, and practices regarding cross-infection control among dental laboratory technicians in Bulgaria: a cross-sectional study. [PDF]
BMC Oral HealthKalpakchieva N, Dokova K.
europepmc +1 more source
Development‐based In Vivo Bioreactor Strategy for Challenging Senescent Bone Reconstruction
Advanced Science, EarlyView.We present a development‐based in vivo bioreactor strategy to generate rejuvenated bone grafts (vBR‐Bone) within aged hosts. By enclosing vBR‐Bone fragments within an asymmetric biomimetic periosteum, segmental femoral defects in aged mice were successfully repaired within 6 weeks. Mechanistically, the multifactors of vBR‐Bone reconstitute a remodeling
Wenchao Zhang +9 more
wiley +1 more source