Results 241 to 250 of about 409,931 (354)

Auditory Hair Cell Mechanotransduction Channels Dynamically Shape the Mechanical Properties of Their Membrane Environment

Advanced Science, EarlyView.
This work shows, for the first time, that the stereocilia membrane in cochlear hair cells is dynamically regulated by the mechanotransduction channel to impact the membrane mechanical properties. This work provides direct evidence that the opening and closing associated with the MET channel is regulating the membrane viscosity suggesting that the MET ...
Shefin S. George, Anthony J. Ricci
wiley   +1 more source

Regenerative teeth induced by in vitro mesenchymal cells in mice via repressing BMP4 and activating retinoic acid/osteopontin. [PDF]

Cell Regen
Chen S, Zhao Y, Chu H, Mo Q, Zhang J, Chen X, Zhang Y, Li X, Wu D, Liu P, Feng B, Qin D, Wang Y, Pei D, Cai J.   +14 more
europepmc   +1 more source

Treatment with Minicircle DNA Expressing a FGF23 Fragment in a Clinically relevant Mouse Model of X‐Linked Hypophosphatemic Rickets

Advanced Science, EarlyView.
The pathogenic role of PHEX isn't fully determined, and there is no radical cure for X‐linked hypophosphatemic rickets (XLHR). This study makes the first attempt to perform gene therapy using a minicircle DNA (MC‐DNA) vector expressing a fragment of FGF23 (amino acids 180‐251) in Phex‐T1349C mice and suggests MC‐DNA as a promisingly safe and effective ...
Huixiao Wu, Wanyi Zhao, Xinyu Chen, Yanzhou Wang, Shuoshuo Wei, Bo Xiang, Yingzhou Shi, Zongyue Li, Yangyang Yao, Jin Xie, Renyuan Qiu, Meng Shu, Shuo Xu, Ping Chen, Zhiying Chen, Yingjie Wu, Weibo Xia, Ling Gao, Yongfeng Song, Jiajun Zhao, Chao Xu   +20 more
wiley   +1 more source

Minimally Invasive Esthetic Treatments With an Orthorestorative Integrated Digital Approach: A Case Report. [PDF]

Case Rep Dent
D'Arcangelo C, Buonvivere M, Vadini M, De Angelis F.   +3 more
europepmc   +1 more source

Zirconia Resin-bonded Bridges: An Alternative Approach for Minimally Invasive Dental Prostheses Using the Computer-aided Design/Computer-aided Manufacturing Technology: A Case Report

El Yamani Amal, Mabrouk Sara, Dabla Fahd
openalex   +1 more source

Imaging of the Jaws [PDF]

, 2015
Koenig, Lisa J.
core   +1 more source

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

Advanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang, Xiaoyu Zhou, Mengdan Li, Chao Zhang, Haiyan Xu, Jingyi He, Li Zhan, Yueling Gu, Hao Gu, Tianyu Tu, Hanfang Liu, Taotao Lu, Yueming Zheng, Jian Li, Zhaobing Gao, Yixiang Xu   +15 more
wiley   +1 more source

Readiness of parents to attend first dental visit within three years of child's age: An analysis applying Anderson's behavior model of health and utilization. [PDF]

J Educ Health Promot
Keerthi VS, Siluvai S, Mugunthan SR, Indumathi KP, Krishnaprakash G, Rakesh VL.   +5 more
europepmc   +1 more source

Single‐Field Evolution Rule Governs the Dynamics of Representational Drift in Mouse Hippocampal Dorsal CA1 Region

Advanced Science, EarlyView.
Long‐term hippocampal place‐code dynamics are investigated using calcium imaging across weeks of maze navigation. Analyses reveal a novelty‐irrelevant Single‐Field Evolution Rule (SFER), where active fields promote persistence and inactive fields decline.
Cong Chen, Shuyang Yao, Sihui Cheng, Jiayi Tian, Ang Li, Yusen Yan, Xiang Zhang, Yuanjing Liu, Yumeng Wang, Qichen Cao, Chenglin Miao   +10 more
wiley   +1 more source

Advanced Dental Materials: From Design to Application-Second Edition. [PDF]

Materials (Basel)
Kranjčić J, Poklepović Peričić T.
europepmc   +1 more source