Results 171 to 180 of about 183,859 (349)

Mapping the Tissue‐of‐Origins of Mesenchymal Stromal Cells in Injury Repair

Advanced Science, EarlyView.
This study maps mesenchymal stromal cells (MSCs) across multiple tissues, revealing that bone marrow–derived MSCs mobilize monocytes via CCL2 to promote systemic inflammation but do not migrate to distant organs to form fibrotic or tumor stroma. Instead, local MSCs dominate tissue remodeling, suggesting a “two‐hit” model linking systemic inflammation ...
Xinyu Thomas Tang, Yiming Liam Liu, Yidi Augenstern Du, Shan−Shan Wang, Bo O. Zhou   +4 more
wiley   +1 more source

Cinnamic‐Hydroxamic‐Acid Derivatives Exhibit Antibiotic, Anti‐Biofilm, and Supercoiling Relaxation Properties by Targeting Bacterial Nucleoid‐Associated Protein HU

Advanced Science, EarlyView.
Cinnamic‐hydroxamic‐acid derivatives (CHADs) are identified as novel inhibitors of the bacterial nucleoid‐associated protein HU, exhibiting potent antibacterial, anti‐biofilm (both inhibition and eradication), and DNA relaxation (anti‐supercoiling) activities. Moreover, CHADs demonstrate strong synergistic effects with multiple antibiotics.
Huan Chen, Yingqi Xu, Zhaoping Xiong, Hongliang Wang, Xin Wang, Yue Kang, Zhonglin Wang, Xiaoyan Zeng, Yahui Liu, Yehuan Zheng, Wei Chen, Mengzhe Li, Zhenyue Hu, Chi Xu, Yue Wu, Yawen Wang, Zuyi Yuan, Shuai Yuan, Huadong Liu, Steve Matthews, Nan Qiao, Yan Li, Bing Liu   +22 more
wiley   +1 more source

TMEM131‐Mediated Soluble TRAIL Triggered Type II Alveolar Epithelial Cell Senescence in Radiation‐Induced Lung Injury

Advanced Science, EarlyView.
TMEM131 recruits the COPII complex to accelerate TRAIL transportation from endoplasmic reticulum to Golgi apparatus, and promotes soluble TRAIL secretion. TRAIL inhibits mitophagy and induces senescence through DR5 receptor in type II alveolar epithelial cells, ultimately driving radiation‐induced lung injury (RILI) progression.
Linzhi Han, Chunsheng Wang, Xiuli Guo, Yuan Luo, Jianguo Zhang, Fajian He, Zihang Zeng, Jiang Luo, Wen Ouyang, Yan Gong, Conghua Xie   +10 more
wiley   +1 more source

Knowledge and Attitude of Dental Trauma Among Dental Students in Thrace Region of Turkiye [PDF]

Journal of Oral Health and Oral Epidemiology
Background and aimThe study aimed to determine the level of knowledge of Trakya University Faculty of Dentistry 4th and 5th grade students about the diagnosis and clinical management of dental traumatic injuries and to evaluate the effects of factors ...
İrem Çetinkaya, Neslihan Ozveren
doaj  

Revisión bibliográfica sobre trauma dental en niños [PDF]

, 2009
Dra. Yasmilda Maria Leyva Labrador, Dra. Yismai Baile Labrador, Dra. Adisnubia Ribeaux Chibás, Dra. Elizabeth Rodríguez Trejo, Dra. Deysi Suárez Zafra, Dra. Nivia Sánchez Fernández, Miroslava Castellanos González   +6 more
openalex  

Human Atlas of Tooth Decay Progression: Identification of Cellular Mechanisms Driving the Switch from Dental Pulp Repair Toward Irreversible Pulpitis

Advanced Science, EarlyView.
Tooth decay progression transforms the dental pulp response from repair to fibrosis. At early stages, stromal cells reprogram to repair the extra cellular matrix (ECM), blood vessels, and nerves, remodel and grow, keeping repair possible. In advanced decay, hypoxia, and vessel regression, in complement with an immune switch, fuel nerve degeneration and
Hoang Thai Ha, Sofya Kosmynina, Amandine Verocq, Keremsah Ozen, Ines Tekia, Hugo Bussy, Marie Ramirez, Dima Sabbah, Chloe Goemans, Valerie Vandenbempt, Esteban N. Gurzov, Sumeet Pal Singh, Nicolas Baeyens   +12 more
wiley   +1 more source

Trauma to the Temporomandibular Joint Following Tooth Extraction via Dental Students

, 2011
Mohammad Ali Dolatabadi, Esshagh Lassemi
openalex   +2 more sources

Efficacy assessment of laser Doppler imager in diagnosing the pulp vitality after dental trauma

, 2022
Hui-Na Lee, Ping‐Ho Chen, Chun-Yin Huang, Chun‐Ming Chen, Jiiang‐Huei Jeng, Yuk-Kwan Chen, Fu-Hsiung Chuang   +6 more
openalex   +1 more source

Site‐Specific Mitochondrial RNA N1‐Methyladenosine Demethylation via an Engineered MTS‐PUF‐ALKBH3 Fusion Protein

Advanced Science, EarlyView.
A CRISPR‐free mitochondrial RNA m1A demethylation (MRD) editor combining MTS, PUF proteins, and ALKBH3 enables precise m1A removal from mitochondrial mRNA and tRNA, which influences mitochondrial protein levels, cellular proliferation, ATP production, and mitochondrial respiration. Subsequently, in vivo demethylation of the m1A modification is achieved
Xiangrui Li, Deqiang Kong, Hongmei Liu, Jie Yang, Jiale Zhou, Yuqiang Qian, Ding Zhao, Jinze Li, Xinyu Wu, Tao Zhang, Xiaodi Sun, Yang Han, Liangxue Lai, Zhanjun Li   +13 more
wiley   +1 more source

Targeting Itga8 Mitigates Neurogenic Bladder Fibrosis Driven by Trem2⁺ Macrophage‐Derived Fn1 via FAK/RhoA/ROCK Signaling

Advanced Science, EarlyView.
Normal bladders exhibit quiescent fibroblasts/macrophages, whereas neurogenic bladders show acute‐phase Itga8⁺ fibroblast expansion driven by Trem2⁺ macrophage‐secreted Fn1, which activates FAK/RhoA/ROCK signaling, promotes cytoskeletal remodeling, and upregulates pro‐fibrotic genes.
Jiaxin Wang, Siyuan Wang, Lida Ren, Xinqi Liu, Lei Zhang, Peng Hu, Wenchao Xu, Shuaixiang Zheng, Jihong Liu, Qing Ling   +9 more
wiley   +1 more source