Results 171 to 180 of about 64,936 (312)

Site‐Specific Mitochondrial RNA N1‐Methyladenosine Demethylation via an Engineered MTS‐PUF‐ALKBH3 Fusion Protein

open access: yesAdvanced Science, EarlyView.
A CRISPR‐free mitochondrial RNA m1A demethylation (MRD) editor combining MTS, PUF proteins, and ALKBH3 enables precise m1A removal from mitochondrial mRNA and tRNA, which influences mitochondrial protein levels, cellular proliferation, ATP production, and mitochondrial respiration. Subsequently, in vivo demethylation of the m1A modification is achieved
Xiangrui Li   +13 more
wiley   +1 more source

Should we recommend early overjet reduction to prevent dental trauma? [PDF]

open access: yesBr Dent J, 2022
Cobourne MT   +3 more
europepmc   +1 more source

Parabiosis, Assembloids, Organoids (PAO)

open access: yesAdvanced Science, EarlyView.
This review evaluates parabiosis, organoids, and assembloids as complementary disease models spanning systemic, organ, and multi‐organ levels. It highlights their construction strategies, applications, and current limitations, while emphasizing their integration with frontier technologies such as artificial intelligence, organ‐on‐a‐chip, CRISPR, and ...
Yang Hong   +5 more
wiley   +1 more source

Detection rate of dental trauma and maxillofacial injuries in high-energy polytrauma patients on total body CT: incidence and underestimation. [PDF]

open access: yesEmerg Radiol
Lucarelli NM   +8 more
europepmc   +1 more source

Dental trauma and oral health-related quality of life in schoolchildren from public schools of a southern Brazilian city [PDF]

open access: diamond, 2018
Abelardo Nunes Lunardelli   +6 more
openalex   +1 more source

Punicalagin Enhances Autophagy Through Sirtuin 1/FoxO3a Axis to Inhibit Intracellular Mycobacterium Abscessus Infection

open access: yesAdvanced Science, EarlyView.
Punicalagin, a pomegranate molecule, helps the body fight Mycobacterium abscessus. It preferentially boosts interstitial macrophages in the lung, stabilizing mitochondria and switching on the autophagy via SIRT1/FoxO3a, which lowers bacterial load without directly killing bacteria.
Kefan Bi   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy