Results 241 to 250 of about 1,291,272 (353)

FOXM1 Protects Against Myocardial Ischemia‐Reperfusion Injury in Rodent and Porcine Models by Suppressing MKRN1‐Dependent LKB1 Ubiquitination

open access: yesAdvanced Science, EarlyView.
FOXM1 maintains mitochondrial bioenergetic function by inhibiting MKRN1‐mediated ubiquitination of LKB1 in cardiomyocytes. Loss of FOXM1 in cardiomyocytes results in upregulation of MKRN1, which enhances LKB1 ubiquitination and disrupts AMPK signaling and energy metabolism pathways. Conversely, FOXM1 overexpression preserves mitochondrial bioenergetics
Shuai Song   +17 more
wiley   +1 more source

Biocompatible Mesoporous Materials for Bone Therapy

open access: yesAdvanced Science, EarlyView.
Biocompatible mesoporous materials (BMMs), characterized by high specific surface area, tunable pore size, different shapes and structures, and multidimensional functionalized modifications, have revolutionary applications in treating bone‐related diseases.
Biao Yu   +6 more
wiley   +1 more source

Regulating Enzyme Activity via Microaggregates Mediated by Phase Separation

open access: yesAdvanced Science, EarlyView.
An enzyme‐sequestration strategy for combating postoperative pancreatic fistula (POPF) is developed, employing a D‐peptide called DPMD to induce liquid–solid phase separation (LSPS) of pancreatic proteases. This LSPS‐driven microaggregate approach effectively isolates trypsin and chymotrypsin from their substrates, thereby reducing pancreatic fluid ...
Yang Wang   +7 more
wiley   +1 more source

Is there an association between the presence of dental fluorosis and dental trauma amongst school children [PDF]

open access: gold, 2016
Lorenna Fonseca Braga de Oliveira   +6 more
openalex  

Modulation of Aging Diseases via RAGE Targets: A Dietary Intervention Review

open access: yesAdvanced Science, EarlyView.
This paper analyzes RAGE ligand‐binding mechanisms and signaling, proposing intervention strategies targeting these interactions. It emphasizes dietary polyphenols, polysaccharides, and terpenoids delivered via functional foods for anti‐aging. These compounds offer long‐term, safe intervention through dietary supplementation, providing dual nutritional
Qian Wu   +7 more
wiley   +1 more source

A 12-Year Retrospective Study of Avulsion Cases in a Public Brazilian Dental Trauma Service.

open access: gold, 2017
Gabriela Campos Mesquita   +5 more
openalex   +2 more sources

Knowledge, Attitude, and Behavior toward Dental Trauma among Parents of Primary Schoolchildren Visiting College of Dentistry, Jizan. [PDF]

open access: yesInt J Clin Pediatr Dent
Maganur PC   +7 more
europepmc   +1 more source

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