Results 201 to 210 of about 8,256,293 (302)

ELF5‐Mediated Enhancer–Promoter Interaction Regulates LALBA Expression in Ovine Mammary Gland

open access: yesAdvanced Science, EarlyView.
In the study, we systematically investigate the epigenetic mechanisms underlying lactation traits in sheep by integrating transcriptomic, chromatin accessibility, histone modification, and functional analyses. We identify a super‐enhancer at the LALBA locus and demonstrate that enhancer E4 functions as its core regulatory element.
Xinmiao Wu   +11 more
wiley   +1 more source

Porphyrin‐Based Porous Materials for Antibacterial Applications

open access: yesAdvanced Science, EarlyView.
Porphyrin‐based porous materials have excellent photophysical properties and tunable structures for high‐efficiency antibacterial therapy. This review comprehensively discusses the structural design strategies and synthetic pathways of the four main types of porphyrin‐based porous materials, summarizes their cross‐domain antimicrobial applications, and
Xiao‐Xue Liang   +4 more
wiley   +1 more source

Targeted Mechanogenetics to Modulate Specific Deep Neural Circuits

open access: yesAdvanced Science, EarlyView.
This study introduces mechanogenetics, a nanobubble‐enhanced sonogenetic strategy for selective modulation of feeding‐related neural circuits in the mouse lateral hypothalamus. Mechanogenetic stimulation modulates feeding behavior through glutamatergic projections from the lateral hypothalamus to the ventral tegmental area, highlighting its potential ...
Xuandi Hou   +3 more
wiley   +1 more source

Spatiotemporal Regulation of Hierarchical Assembly of Hydroxyapatite for Enamel Remineralization

open access: yesAdvanced Science, EarlyView.
Biomimetic repair exhibits unique advantages for enamel regeneration compared with conventional clinical treatments. An enzymatic mineralization system (EMS) is developed, where the resulting HAP nanorods hierarchically assemble into a highly ordered structure on the enamel surface through the spatiotemporal modulation of interfacial energies of ...
Zhenhang Tang   +15 more
wiley   +1 more source

Virtual Reality Goggles as a Distraction Technique for Managing Behavioral Conduct During Pulp Pediatric Dental Treatment: A Systematic Review and Meta-Analysis. [PDF]

open access: yesDent J (Basel)
Machuca-Portillo C   +6 more
europepmc   +1 more source

Ultrasound‐Activated Ce(IV)‐Integrated Biomimetic Nanoplatform for Oxygenation‐Reinforced Gas‐Sonodynamic Ferroptosis and cGAS–STING‐Driven Antitumor Immunity

open access: yesAdvanced Science, EarlyView.
A Ce(IV)‐integrated biomimetic nanoplatform coordinates tumor oxygenation, ultrasound‐triggered carbon monoxide release, sonodynamic therapy, ferroptosis amplification, and cyclic GMP–AMP synthase (cGAS)–stimulator of interferon genes (STING) immune activation.
Mengli Ma   +17 more
wiley   +1 more source

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