Confined Migration Drives Stem Cell Differentiation
Human mesenchymal stem cell (hMSC) homing to sites of regeneration requires navigation through mechanically confining extracellular matrix environments, inducing rapid and dramatic morphological adaptation. By exposing hMSCs to specific levels of physiological confinement, it is demonstrated that confinement can induce osteogenesis, and that this fate ...
Xu Gao+6 more
wiley +1 more source
Retrospective analysis of a decade of general anesthesia for dental treatment in patients with disabilities at a regional university dental hospital in South Korea. [PDF]
Shin S.
europepmc +1 more source
Are antibiotics being used appropriately for emergency dental treatment? [PDF]
Y M Dailey, Michael V. Martin
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These findings reveal that silicon exerts strong protective effects in diabetic bone defect models by selectively promoting Drp1‐Mff activity. Silicon facilitates precise regulation of mitochondrial dynamics to enable functional mitochondrial transfer.
Yu‐Xuan Ma+12 more
wiley +1 more source
Intravenous sedation for adults with profound acquired brain injury undergoing dental treatment - a seven-year service evaluation. [PDF]
Doshi M+4 more
europepmc +1 more source
Sevoflurane inhalation conscious sedation for children having dental treatment [PDF]
G. Y. Lahoud, Paul Averley, M. R. Hanlon
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Development of MDM2‐Targeting PROTAC for Advancing Bone Regeneration
This work presents a creative pipeline for developing MDM2‐targeting PROTACs (MDM2‐PROTACs) for application in bone regeneration. The developed PROTACs (CL144 and CL174) are validated for their degradation efficiency and osteogenic effects in human BMSCs.
Sol Jeong+17 more
wiley +1 more source
Parental Perspectives on Paediatric Dental Treatment under General Anaesthesia. [PDF]
Albalooshy AM.
europepmc +1 more source
Eosinophils play a crucial role in the progression of temporomandibular joint osteoarthritis (TMJOA). This study demonstrates that eosinophils, induced by OVA/IL‐5, promote Lumican secretion in the synovium, which binds to Annexin A1 in chondrocytes, inhibiting transforming growth factor β2 and Smad2/3 phosphorylation.
Wenqian Chen+12 more
wiley +1 more source
Oral health status and dental treatment needs in children with autism spectrum disorder. [PDF]
George SS+9 more
europepmc +1 more source