Results 71 to 80 of about 3,007 (251)

A Novel Pak1 Activator Ameliorates ER Stress for HFpEF Therapy

Advanced Science, EarlyView.
Chronic metabolic stress is a major contributor to HFpEF progression. Under prolonged metabolic stress, Pak1 activity becomes impaired, contributing to disrupted ER proteostasis, cardiomyocyte apoptosis, fibrosis, and diastolic dysfunction. Mechanistically, Pak1 overexpression activates the ERK1/2–MNK1–eIF4E signaling axis, promotes translational ...
Honglin Xu, Hongyuan Zhang, Tayyiba Azam, Susanne S. Hille, Yingjuan Liu, Min Zi, Jiaqing Lang, He Yu, Yujia Cao, Bernard D. Keavney, Tamer M. A. Mohamed, Jessica M. Miller, Riham R. E. Abouleisa, Ming Xu, Elizabeth J. Cartwright, Oliver J. Müller, Ming Lei, Xin Wang   +17 more
wiley   +1 more source

User Insights into Fake Snap-on Veneers: Perceptions and Experiences

Clinical, Cosmetic and Investigational Dentistry
Meyassara Samman,1,* Abeer Tashkandi,2 Maha Alsharif,3,* Heba Ashi,1 Lina Bahanan1,* 1Department of Dental Public Health, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia; 2Department of Restorative Dentistry, Faculty of ...
Samman M, Tashkandi A, Alsharif M, Ashi H, Bahanan L   +4 more
doaj  

Bioadhesive‐Integrated 3D‐Printed Multilayer Scaffolds Secure a Mechanically‐Stable Osteoimmune Niche for Enhanced Bone Augmentation

Advanced Science, EarlyView.
A 3D‑printed multilayer adhesive scaffold, firmly anchored to bone defects by simple finger pressing, suppresses micromotion and secures mechanical stability of the osteogenic niche. This stabilization likely contributes to the enhanced bone augmentation by fostering a pro‑regenerative mechano‐immune profile—characterized by M2‑like macrophage ...
Delu Zhao, Qiuyi Li, Lingyun Wang, Chongao Zhang, Yutian Cheng, Shuang Liu, Fulan Wei, Zheqin Dong   +7 more
wiley   +1 more source

Pµsl Fabricates Ultra-Thin And Tough Zirconia Veneers

International Dental Journal
Aim or purpose: To evaluate the feasibility of PµSL technology in fabricating ultra-thin (80 μm) zirconia veneers, optimizing printing parameters for enhanced precision, mechanical strength, and clinical applicability, while minimizing tooth preparation.
Xiang Wang, Yuchun Sun, Chen Yang, Yanru Shen   +3 more
doaj   +1 more source

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

Advanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

Two-Year Clinical Performance of Ultra-Thin No-Prep Veneers from 5Y-TZP Zirconia: A Retrospective Study

Bioengineering
Objective: This retrospective study aimed to evaluate the two-year clinical performance of ultra-thin, no-prep Prettau® Skin zirconia veneers placed in the anterior region of the maxilla and mandible.
Katarzyna Taraszkiewicz-Sulik, Patryk Wiśniewski, Edyta Cywoniuk, Teresa Sierpińska   +3 more
doaj   +1 more source

Minimally invasive approach to diastema closure using lithium disilicate porcelain veneers: clinical report

Brazilian Dental Science, 2018
Numerous advances in dentistry techniques and material have allowed patients to have not only a functional but also an aesthetic smile in a conservative way.
Sofia Chane Buzetto, Priscila Regis Pedreira, Janaina Emanuela Damasceno, Josué Junior Araujo Pierote, Giselle Maria Marchi, Luiz Alexandre Maffei Sartini Paulillo   +5 more
doaj   +1 more source

Improving retention of dental veneers fabricated from an experimental enamel-based biopolymer compared with CAD/CAM hybrid materials. [PDF]

Heliyon, 2023
Piemjai M, Donpinprai C.
europepmc   +1 more source

VlPAG/DRN Microglia Drive Neuropathic Pain‐Induced Depression via a Defined Neuroimmune Axis

Advanced Science, EarlyView.
Peripheral nerve injury (SNI) induces neuropathic pain, activates midbrain microglia, and triggers an NLRP3–IL‐1β–dependent inflammatory cascade. IL‐1β signals through IL‐1R1 on vlPAG/DRN VGLUT2+ neurons (vlPAG/DRNGlu), inducing hyperexcitability and driving the vlPAG/DRNGlu→BNSTGABA circuit to produce the affective component of neuropathic pain ...
Jing Yang, Bing‐Jie Tang, Jia‐Yi Li, Shu‐Lan Xie, Shumin Duan, Junping Chen, Shengmei Zhu, Zhen‐Zhong Xu   +7 more
wiley   +1 more source

Protease‐Triggered Chromogenic Release From Peptide‐Modified Calcium Carbonate Microspheres Enables Colorimetric Detection of Porphyromonas gingivalis Activity

Advanced Science, EarlyView.
We report a chromogenic release‐based assay system with protease‐cleavage peptide‐modified calcium carbonate microspheres for colorimetric detection of Porphyromonas (P.) gingivalis activity. In response to Arg‐specific gingipain secreted by P. gingivalis, the supernatant becomes colored, enabling colorimetric analysis and providing the monitoring of ...
Yuki Hiruta, Zhicheng Jin, Mari Adachi, Lubna Amer, Natalia O. Tjokro, Diego F. Trujillo, Jan Potempa, Anthony J. O'Donoghue, Casey Chen, Jesse V. Jokerst   +9 more
wiley   +1 more source