Results 101 to 110 of about 64,673 (113)
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Small, 2022
Alzheimer's disease (AD), as a progressive and irreversible brain disorder, remains the most universal neurodegenerative disease. No effective therapeutic methods are established yet due to the hindrance of the blood-brain barrier (BBB) and the complex ...
Xiaotong Yang +8 more
semanticscholar +1 more source
Alzheimer's disease (AD), as a progressive and irreversible brain disorder, remains the most universal neurodegenerative disease. No effective therapeutic methods are established yet due to the hindrance of the blood-brain barrier (BBB) and the complex ...
Xiaotong Yang +8 more
semanticscholar +1 more source
Intranasal Oxytocin in the Treatment of Autism Spectrum Disorders: A Multilevel Meta-Analysis.
Neuroscience and Biobehavioral Reviews, 2021Intranasal oxytocin has been shown to promote social functioning and has recently been applied as a treatment for autism spectrum disorders (ASD). The current meta-analysis aims to assess the crucial question of oxytocin's efficacy in the treatment of ...
Yi Huang +3 more
semanticscholar +1 more source
Intranasal drug delivery: The interaction between nanoparticles and the nose-to-brain pathway.
Advanced Drug Delivery ReviewsWe overviewed the anatomy and physiology of the nose-to-brain pathway, along with the mechanisms involved. We then summarized the interaction process between nanoparticles and this pathway as well as the potential strategies inspired from natural nano ...
Yaoxing Chen +7 more
semanticscholar +1 more source
Advances and future perspectives of intranasal drug delivery: A scientometric review.
Journal of Controlled ReleaseIntranasal drug delivery is as a noninvasive and efficient approach extensively utilized for treating the local, central nervous system, and systemic diseases.
Dong Xu +4 more
semanticscholar +1 more source
Intranasal vaccine: factors to consider in research and development.
International journal of pharmaceutics, 2021Most existing vaccines for human use are administered by needle-based injection. Administering vaccines needle-free intranasally has numerous advantages over by needle-based injection, but there are only a few intranasal vaccines that are currently ...
Haiyue Xu +3 more
semanticscholar +1 more source
The effect of intravenous, intranasal, and oral ketamine in mood disorders: A meta-analysis.
Journal of Affective Disorders, 2020BACKGROUND Ketamine is established as a rapid and effective treatment in adults with treatment-resistant depression (TRD). The availability of different formulations and routes of delivery invites the need for evaluating relative effect sizes.
R. McIntyre +20 more
semanticscholar +1 more source