Results 101 to 110 of about 56,940 (111)

Percepção de crianças em dentição mista e de seus responsáveis quanto a presença do primeiro molar permanente e a situação clínica do dente [PDF]

, 2019
Barcelos, Joice Fonseca, Costa, Izadora Paula Estanislau da, Faria, Larissa dos Santos, Ferreira, Fernanda de Morais, Freire-Maia, Fernanda Bartolomeo, Lenzi, Tathiane Larissa, Miranda, Juliana Freire-Maia, Pordeus, Isabela Almeida   +7 more
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Efficacy and Safety of Intranasal Esketamine Adjunctive to Oral Antidepressant Therapy in Treatment-Resistant Depression: A Randomized Clinical Trial

JAMA psychiatry, 2017
E. Daly, Jaskaran Singh, M. Fedgchin, K. Cooper, P. Lim, R. Shelton, M. Thase, A. Winokur, L. van Nueten, H. Manji, W. Drevets   +10 more
semanticscholar   +1 more source

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Intranasal Administration of Self-Oriented Nanocarriers Based on Therapeutic Exosomes for Synergistic Treatment of Parkinson's Disease.

ACS Nano, 2022
The treatment of Parkinson's disease (PD) has been hindered by the complex pathologies and multiple membrane barriers during drug delivery. Although exosomes derived from mesenchymal stem cells (MSCs) have great potential for PD, MSC-derived exosomes ...
Huan Peng, Yan Li, Weihong Ji, Ruichen Zhao, Zhiguo Lu, Jie Shen, Yanyue Wu, Jianze Wang, Qiulian Hao, Jingwen Wang, Wenli Wang, Jun Yang, Xin Zhang   +12 more
semanticscholar   +1 more source

Intranasal Delivery of BACE1 siRNA and Rapamycin by Dual Targets Modified Nanoparticles for Alzheimer's Disease Therapy.

Small, 2022
Alzheimer's disease (AD), as a progressive and irreversible brain disorder, remains the most universal neurodegenerative disease. No effective therapeutic methods are established yet due to the hindrance of the blood-brain barrier (BBB) and the complex ...
Xiaotong Yang, Wenqin Yang, Xue Xia, Ting Lei, Zhihang Yang, Wenfeng Jia, Yang Zhou, G. Cheng, Huile Gao   +8 more
semanticscholar   +1 more source

Intranasal Delivery of Temozolomide-Conjugated Gold Nanoparticles Functionalized with Anti-EphA3 for Glioblastoma Targeting.

Molecular Pharmaceutics, 2021
Glioblastoma multiforme (GBM) is a highly lethal and aggressive tumor of the brain that carries a poor prognosis. Temozolomide (TMZ) has been widely used as a first-line treatment for GBM.
Liangxiao Wang, Shengnan Tang, Yawen Yu, Yanan Lv, Aiping Wang, Xiuju Yan, Nuannuan Li, Chunjie Sha, Kaoxiang Sun, Youxin Li   +9 more
semanticscholar   +1 more source

Intranasal drug delivery for treatment of Alzheimer’s disease

Drug Delivery and Translational Research, 2021
Leonor C Fonseca, João A Lopes, João Vieira, C. Viegas, C. S. Oliveira, R. P. Hartmann, P. Fonte   +6 more
semanticscholar   +1 more source