Results 21 to 30 of about 57,495 (112)

Intranasal priming induces local lung-resident B cell populations that secrete protective mucosal antiviral IgA

Science immunology, 2021
Description A heterogeneous population of cells secreting mucosal IgA confers protection against influenza virus infection. Flu defense via lung-resident IgA+ memory B cells Secretory IgA antibody is known to be a key effector molecule in establishing ...
Ji-Eun Oh, E. Song, Miyu Moriyama, P. Wong, Sophia Zhang, Ruoyi Jiang, Shirin Strohmeier, S. Kleinstein, F. Krammer, A. Iwasaki   +9 more
semanticscholar   +1 more source

Hormone replacement therapy in hypopituitarism [PDF]

, 2003
This article brings an updated review of hypopituitarism with emphasis in hormone replacement therapy. The physiological basis of hormone replacement therapy and practical aspects of treating hypopituitary patients were both taken into account to provide
Abucham, Julio, Barbosa, Erika Ribeiro, Martins, Manoel R. Alves, Ribeiro, Rogério Silicani, Vieira, Teresa C. Alfinito   +4 more
core   +3 more sources

Intranasal Oxytocin in Children and Adolescents with Autism Spectrum Disorder.

New England Journal of Medicine, 2021
BACKGROUND Experimental studies and small clinical trials have suggested that treatment with intranasal oxytocin may reduce social impairment in persons with autism spectrum disorder.
L. Sikich, A. Kolevzon, B. King, C. McDougle, Kevin Sanders, Soo-Jeong Kim, Marina Spanos, Tara Chandrasekhar, M. P. Trelles, Carol M Rockhill, Michelle L Palumbo, Allyson Witters Cundiff, Alicia K. Montgomery, P. Siper, M. Minjarez, L. Nowinski, Sarah Marler, Lauren C. Shuffrey, Cheryl Alderman, Jordana Weissman, Brooke Zappone, Jennifer E. Mullett, Hope Crosson, Natalie Hong, Stephen K Siecinski, Stephanie N. Giamberardino, Sheng Luo, Lilin She, M. Bhapkar, Russell Dean, A. Scheer, Jacqueline L Johnson, S. Gregory, J. Veenstra-VanderWeele   +33 more
semanticscholar   +1 more source

Intranasal fusion inhibitory lipopeptide prevents direct-contact SARS-CoV-2 transmission in ferrets

Science, 2021
Halting transmission The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) glycoprotein binds to host cells and initiates membrane fusion and cell infection.
R. D. de Vries, K. Schmitz, F. Bovier, Camilla Predella, Jonathan Khao, D. Noack, B. Haagmans, S. Herfst, Kyle N. Stearns, Jennifer Drew-Bear, S. Biswas, B. Rockx, G. McGill, N. Dorrello, S. Gellman, C. Alabi, R. D. de Swart, A. Moscona, M. Porotto   +18 more
semanticscholar   +1 more source

Intranasal Insulin for Alzheimer’s Disease

CNS Drugs, 2021
Brain insulin signaling contributes to memory function and might be a viable target in the prevention and treatment of memory impairments including Alzheimer’s disease.
M. Hallschmid
semanticscholar   +1 more source

Asthmatics as a susceptible population in health risk assessment of airborne chemicals [PDF]

, 2016
Asthma is a common chronic airway disease and about 235-300 million individuals of all ages are affected by the disease around the world. A precondition of asthma has been suggested to increase individual susceptibility to acute exposure from airborne ...
Johansson, Mia
core   +1 more source

Vacinas anticárie [PDF]

, 2013
Projeto de Pós-Graduação/Dissertação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Ciências FarmacêuticasA cárie dentária é uma das doenças infecciosas mais comum no homem.
Santos, Joana Gouveia dos
core   +3 more sources

Safety, Efficacy, and Feasibility of Intranasal Insulin for the Treatment of Mild Cognitive Impairment and Alzheimer Disease Dementia: A Randomized Clinical Trial.

JAMA Neurology, 2020
Importance Insulin modulates aspects of brain function relevant to Alzheimer disease and can be delivered to the brain using intranasal devices. To date, the use of intranasal insulin to treat persons with mild cognitive impairment and Alzheimer's ...
S. Craft, R. Raman, T. Chow, M. Rafii, Chung‐Kai Sun, R. Rissman, M. Donohue, J. Brewer, C. Jenkins, K. Harless, D. Gessert, P. Aisen   +11 more
semanticscholar   +1 more source

An Intranasal OMV-Based Vaccine Induces High Mucosal and Systemic Protecting Immunity Against a SARS-CoV-2 Infection

bioRxiv, 2021
The development of more effective, accessible and easy to administer COVID-19 vaccines next to the currently marketed mRNA, viral vector and whole inactivated vaccines, is essential to curtain the SARS-CoV-2 pandemic.
P. van der Ley, A. Zariri, E. van Riet, D. Oosterhoff, C. Kruiswijk   +4 more
semanticscholar   +1 more source

Breath biomarkers in idiopathic pulmonary fibrosis:A systematic review 11 Medical and Health Sciences [PDF]

, 2019
Background: Exhaled biomarkers may be related to disease processes in idiopathic pulmonary fibrosis (IPF) however their clinical role remains unclear. We performed a systematic review to investigate whether breath biomarkers discriminate between patients
A Mashir, A Sandrini, A Sundarakrishnan, A Ulanowska, AG Fois, AG Paulovich, AM Peel, AM Tager, American Thoracic S, European Respiratory S, American Thoracic Society/European Respiratory Society International Multidisciplinary Consensus Classification of the Idiopathic Interstitial Pneumonias, AU Wells, AU Wells, AU Wells, AU Wells, B Ley, B Ley, BC Wallace, BW Kinder, C Agostini, D Makris, D Moher, E Bargagli, E Bargagli, E Fireman, E Ono, FJ Martinez, FJ Martinez, G Bagnato, G Jenkins, G Raghu, G Raghu, G Raghu, H Ishii, H Lehtonen, H Satoh, HL Petsky, HR Collard, I Ojanguren, IO Rosas, J Guiot, J Hutchinson, J Schildge, J Zhou, JA Bjoraker, JC Rufo, JP Hutchinson, K Hildebrand, K Psathakis, K Toren, KP Tiev, KP Tiev, KR Flaherty, L Guilleminault, L Lehtimaki, LD Bos, M Corradi, M Hogman, MP Schee van der, N Alkhouri, NM Tsoukias, NP Barlo, P Cameli, P Cameli, P Condorelli, P Montuschi, P Paredi, PF Whiting, PI Latsi, PJ Mazzone, R Antonelli Incalzi, R Hubbard, R Hubbard, RA Dweik, RE Girgis, RG Jenkins, RM Bois du, RM Effros, S Chow, S Kanoh, S Scarlata, S Scarlata, SA Kharitonov, SC George, SL Walsh, T Greulich, T Okamoto, TE King Jr, TIPFCR Network, TM Maher, TM Oliveira de, U Kalluri, V Cottin, V Rihak, Y Jegal, Y Shimizu, Y Teng, Y Yamada, Y Zhao, YC Hou, YC Hsu   +99 more
core   +1 more source