Results 31 to 40 of about 64,673 (113)

Breath biomarkers in idiopathic pulmonary fibrosis:A systematic review 11 Medical and Health Sciences [PDF]

open access: yes, 2019
Background: Exhaled biomarkers may be related to disease processes in idiopathic pulmonary fibrosis (IPF) however their clinical role remains unclear. We performed a systematic review to investigate whether breath biomarkers discriminate between patients
A Mashir   +99 more
core   +1 more source

Safety, Efficacy, and Feasibility of Intranasal Insulin for the Treatment of Mild Cognitive Impairment and Alzheimer Disease Dementia: A Randomized Clinical Trial.

open access: yesJAMA Neurology, 2020
Importance Insulin modulates aspects of brain function relevant to Alzheimer disease and can be delivered to the brain using intranasal devices. To date, the use of intranasal insulin to treat persons with mild cognitive impairment and Alzheimer's ...
S. Craft   +11 more
semanticscholar   +1 more source

An Intranasal OMV-Based Vaccine Induces High Mucosal and Systemic Protecting Immunity Against a SARS-CoV-2 Infection

open access: yesbioRxiv, 2021
The development of more effective, accessible and easy to administer COVID-19 vaccines next to the currently marketed mRNA, viral vector and whole inactivated vaccines, is essential to curtain the SARS-CoV-2 pandemic.
P. van der Ley   +4 more
semanticscholar   +1 more source

Neuroinvasion and Encephalitis Following Intranasal Inoculation of SARS-CoV-2 in K18-hACE2 Mice

open access: yesbioRxiv, 2020
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection can cause neurological disease in humans, but little is known about the pathogenesis of SARS-CoV-2 infection in the central nervous system.
P. Kumari   +8 more
semanticscholar   +1 more source

Addition to inhaled corticosteroids of long-acting beta2-agonists versus anti-leukotrienes for chronic asthma [PDF]

open access: yes, 2011
Asthma patients who continue to experience symptoms despite being on regular inhaled corticosteroids (ICS) represent a management challenge. Long-acting beta2-agonists (LABA) or anti-leukotrienes (LTRA) are two treatment options that could be considered ...
Adams   +207 more
core   +1 more source

A single intranasal or intramuscular immunization with chimpanzee adenovirus-vectored SARS-CoV-2 vaccine protects against pneumonia in hamsters

open access: yesCell Reports, 2021
The development of an effective vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiologic agent of coronavirus disease 2019 (COVID-19), is a global priority.
T. Bricker   +15 more
semanticscholar   +1 more source

Single-Dose Intranasal Administration of AdCOVID Elicits Systemic and Mucosal Immunity against SARS-CoV-2 and Fully Protects Mice from Lethal Challenge

open access: yesVaccines, 2021
The coronavirus disease 2019 (COVID-19) pandemic has highlighted the urgent need for effective prophylactic vaccination to prevent the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
R. King   +35 more
semanticscholar   +1 more source

Transnasal Removal of Ectopic Supernumerary Tooth from Cleft Patient [PDF]

open access: yes, 2015
Background: The ectopic teeth can be permanent, deciduous or supernumerary and they are changes caused by the morphogenesis and growth of tissue outside their common positions. The ectopic inclusions occur in about 1% of the population.
Pita Neto, Ivo Cavalcante   +8 more
core   +2 more sources

Recent Advances in Intranasal Administration for Brain-Targeting Delivery: A Comprehensive Review of Lipid-Based Nanoparticles and Stimuli-Responsive Gel Formulations

open access: yesInternational Journal of Nanomedicine
Addressing disorders related to the central nervous system (CNS) remains a complex challenge because of the presence of the blood-brain barrier (BBB), which restricts the entry of external substances into the brain tissue.
Jain Koo, Chaemin Lim, Kyung Taek Oh
semanticscholar   +1 more source

Marijuana: Current Concepts† [PDF]

open access: yes, 2013
Marijuana (cannabis) remains a controversial drug in the twenty-first century. This paper considers current research on use of Cannabis sativa and its constituents such as the cannabinoids.
Donald E. Greydanus   +3 more
core   +3 more sources

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