Results 41 to 50 of about 57,495 (112)

Intranasal insulin

open access: yesJournal of neuroendocrinology, 2021
The intranasal (IN) route enables the delivery of insulin to the central nervous system in the relative absence of systemic uptake and related peripheral side effects.
M. Hallschmid
semanticscholar   +1 more source

The clinical effectiveness and cost-effectiveness of inhaler devices used in the routine management of chronic asthma in older children: a systematic review and economic evaluation [PDF]

open access: yes, 2002
Background: This review examines the clinical effectiveness and cost-effectiveness of hand-held inhalers to deliver medication for the routine management of chronic asthma in children aged between 5 and 15 years.
Beverley, C.   +4 more
core   +1 more source

Intranasal delivery of mitochondria for treatment of Parkinson’s Disease model rats lesioned with 6-hydroxydopamine

open access: yesScientific Reports, 2021
The feasibility of delivering mitochondria intranasally so as to bypass the blood–brain barrier in treating Parkinson's disease (PD), was evaluated in unilaterally 6-OHDA-lesioned rats. Intranasal infusion of allogeneic mitochondria conjugated with Pep-1
Juichih Chang   +8 more
semanticscholar   +1 more source

Intranasal Zolmitriptan-Loaded Bilosomes with Extended Nasal Mucociliary Transit Time for Direct Nose to Brain Delivery

open access: yesPharmaceutics, 2021
This study aimed at delivering intranasal zolmitriptan directly to the brain through preparation of bilosomes incorporated into a mucoadhesive in situ gel with extended nasal mucociliary transit time.
M. M. El Taweel   +3 more
semanticscholar   +1 more source

Farmacología de los opioides [PDF]

open access: yes, 2005
En los últimos años se ha avanzado en el conocimiento de la farmacología de los opioides. Los opioides endógenos y exógenos se unen a receptores específicos. Existen cuatro tipos de receptores opioides; mu, kappa, delta y nociceptina.
Alvarez García, Yolanda, Farre, Magi
core   +1 more source

Advances in the field of intranasal oxytocin research: lessons learned and future directions for clinical research

open access: yesMolecular Psychiatry, 2020
Reports on the modulatory role of the neuropeptide oxytocin on social cognition and behavior have steadily increased over the last two decades, stimulating considerable interest in its psychiatric application.
D. Quintana   +5 more
semanticscholar   +1 more source

Intranasal Administration of RBD Nanoparticles Confers Induction of Mucosal and Systemic Immunity against SARS-CoV-2

open access: yesVaccines, 2021
Mucosal immunity plays a significant role in host defense against viruses in the respiratory tract. Because the upper respiratory airway is a primary site of SARS-CoV-2 entry, immunization at the mucosa via the intranasal route could potentially lead to ...
Tuksin Jearanaiwitayakul   +8 more
semanticscholar   +1 more source

Etiopatogenia de la osteonecrosis idiopática de cadera: situación actual [PDF]

open access: yes, 2009
Al margen de las numerosas hipótesis etiopatogénicas sobre la osteonecrosis atraumática de cadera, la fisiopatología de la enfermedad sigue siendo, en la actualidad, motivo de debate.
Escribá, I.   +2 more
core  

Overcoming the challenges of developing an intranasal diazepam rescue therapy for the treatment of seizure clusters

open access: yesEpilepsia, 2021
Seizure clusters must be treated quickly and effectively to prevent progression to prolonged seizures and status epilepticus. Rescue therapy for seizure clusters has focused on the use of benzodiazepines.
J. Cloyd   +3 more
semanticscholar   +1 more source

Organ-specific allergen challenges in airway allergy: Current utilities and future directions [PDF]

open access: yes, 2023
Atopy has been long used as the screening method for airway allergy. Nevertheless, aeroallergens can trigger respiratory symptoms not only in atopic patients (atopic res piratory allergy, ARA), but also in non-atopic subjects (local respiratory allergy ...
Alba-Linero, Carmen   +8 more
core   +1 more source

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