Results 41 to 50 of about 56,940 (111)

Transnasal Removal of Ectopic Supernumerary Tooth from Cleft Patient [PDF]

, 2015
Background: The ectopic teeth can be permanent, deciduous or supernumerary and they are changes caused by the morphogenesis and growth of tissue outside their common positions. The ectopic inclusions occur in about 1% of the population.
Pita Neto, Ivo Cavalcante, Franco, Jeférson Martins Pereira Lucena, Bringel, Romildo José de Siqueira, Santana, Milana Drumond Ramos, Batista, Hermes Melo Teixeira, Pita, Pablo, Soares, Eduardo Costa Studart, de Abreu, Luiz Carlos, Rodrigues, Luciano Miller Reis   +8 more
core   +2 more sources

Neuroinvasion and Encephalitis Following Intranasal Inoculation of SARS-CoV-2 in K18-hACE2 Mice

bioRxiv, 2020
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection can cause neurological disease in humans, but little is known about the pathogenesis of SARS-CoV-2 infection in the central nervous system.
P. Kumari, H. Rothan, Janhavi Natekar, S. Stone, H. Pathak, Philip G. Strate, K. Arora, M. Brinton, Mukesh Kumar   +8 more
semanticscholar   +1 more source

Intranasal Administration of RBD Nanoparticles Confers Induction of Mucosal and Systemic Immunity against SARS-CoV-2

Vaccines, 2021
Mucosal immunity plays a significant role in host defense against viruses in the respiratory tract. Because the upper respiratory airway is a primary site of SARS-CoV-2 entry, immunization at the mucosa via the intranasal route could potentially lead to ...
Tuksin Jearanaiwitayakul, Mathurin Seesen, R. Chawengkirttikul, Jitra Limthongkul, Suttikarn Apichirapokey, S. Sapsutthipas, S. Phumiamorn, P. Sunintaboon, S. Ubol   +8 more
semanticscholar   +1 more source

Addition to inhaled corticosteroids of long-acting beta2-agonists versus anti-leukotrienes for chronic asthma [PDF]

, 2011
Asthma patients who continue to experience symptoms despite being on regular inhaled corticosteroids (ICS) represent a management challenge. Long-acting beta2-agonists (LABA) or anti-leukotrienes (LTRA) are two treatment options that could be considered ...
Adams, Adinoff, Altman, Anonymous, Anonymous, Anonymous, Baraniuk, Barnes, Bateman, Bateman, Becker, Bergmann, Bjermer, Bjermer, Bjermer, Bleecker, Borker, Boulet, Bousquet, Brabson, Buchvald, Buchvald, Buhl, Busse, Caffey, Calhoun, Calhoun, Cash, Cates, Ceylan, Chopra, Chuchalin, Covar, Currie, Currie, Currie, Davies, Davis, Deeks, Dekhuijzen, Delaronde, Dempsey, Deykin, Dicpinigaitis, Donohue, Dorinsky, Dorinsky, Dorinsky, Dorinsky, Ducharme, Ducharme, Ducharme, Ducharme, Dunn, Edelman, Edin, Egger, Eliraz, Eliraz, Ernst, Everden, Fish, Fish, Gabrijelcic, Georgitis, Giannini, Gold, Gold, Green, Green, Green, Grosclaude, Grzelewska-Rzymowska, Gupta, Havlucu, Hendeles, Higgins, Higgins, Horwitz, Houghton, Ilowite, Inoue, Jarvis, Jarvis, Jenkins, Johnson, Jonsson, Kalberg, Kalberg, Kanniess, Kanniess, Karaman, Kardos, Keith, Kemp, Keonig, Kerwin, Knobil, Knorr, Koenig, Kohrogi, Krawiec, Larsen, Laviolette, Lazarus, Lee, Lee, Lee, Lee, Leflein, Leibman, Leibman, Lemanske, Lipworth, Lipworth, Liu, Lotvall, Lougheed, Maspero, Maspero, Maspero, McCarthy, McCarthy, Meltzer, Miraglia del Giudice, Mitchell, Molitor, Naedele-Risha, Nathan, Nathan, Nathan, Nathan, Nathan, Nelson, Nelson, Nelson, Nelson, Nelson, Ni Chroinin, Ni Chroinin, Nsouli, O'Connor, O'Sullivan, Ohbayashi, Ohbayashi, Ollendorf, Oppenheimer, Orgega-Cisneros, Paterson, Pavord, Pearlman, Perera, Perez, Peroni, Peroni, Petermann, Peters, Pieters, Pieters, Plaza, Polos, Powell, Price, Ram, Reddel, Rees, Riccioni, Rickard, Rickard, Ringdal, Ringdal, Rosenhall, Salpeter, Serrier, Sheth, Sims, Sims, Sims, Smith, Sorkness, Stanford, Stelmach, Stelmach, Stelmach, Stelmach, Stelmach, Stelmach, Stempel, Stempel, Stevenson, Storms, Storms, Terzano, Thien, Tolley, Vaquerizo, Volovitz, Walters, Warner, Wasserman, Wenzel, Wilson, Wilson, Wilson, Wytrychowski, Yurdakul, Zarkovic, Zimmerman   +207 more
core   +1 more source

Recent Advances in Intranasal Administration for Brain-Targeting Delivery: A Comprehensive Review of Lipid-Based Nanoparticles and Stimuli-Responsive Gel Formulations

International Journal of Nanomedicine
Addressing disorders related to the central nervous system (CNS) remains a complex challenge because of the presence of the blood-brain barrier (BBB), which restricts the entry of external substances into the brain tissue.
Jain Koo, Chaemin Lim, K. Oh
semanticscholar   +1 more source

Overcoming the challenges of developing an intranasal diazepam rescue therapy for the treatment of seizure clusters

Epilepsia, 2021
Seizure clusters must be treated quickly and effectively to prevent progression to prolonged seizures and status epilepticus. Rescue therapy for seizure clusters has focused on the use of benzodiazepines.
J. Cloyd, S. Haut, E. Carrazana, A. Rabinowicz   +3 more
semanticscholar   +1 more source

Intranasal delivery of mesenchymal stem cell‐derived extracellular vesicles exerts immunomodulatory and neuroprotective effects in a 3xTg model of Alzheimer's disease

Stem Cells Translational Medicine, 2020
The critical role of neuroinflammation in favoring and accelerating the pathogenic process in Alzheimer's disease (AD) increased the need to target the cerebral innate immune cells as a potential therapeutic strategy to slow down the disease progression.
M. Losurdo, M. Pedrazzoli, C. D'Agostino, C. Elia, F. Massenzio, E. Lonati, Mario Mauri, L. Rizzi, L. Molteni, E. Bresciani, E. Dander, G. D'Amico, A. Bulbarelli, A. Torsello, M. Matteoli, M. Buffelli, S. Coco   +16 more
semanticscholar   +1 more source

Intranasal Transplantation of Human Neural Stem Cells Ameliorates Alzheimer's Disease-Like Pathology in a Mouse Model

Frontiers in Aging Neuroscience, 2021
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by memory impairments, which has no effective therapy. Stem cell transplantation shows great potential in the therapy of various disease. However, the application of stem cell therapy
Mei-Hong Lu, Wen-Li Ji, Hong Chen, Yanyun Sun, Xiu-Yun Zhao, Fen Wang, Yi Shi, Yan-Ning Hu, Boyan Liu, Jing-wen Wu, De-En Xu, Jia-wei Zheng, Chun-Feng Liu, Quan-Hong Ma   +13 more
semanticscholar   +1 more source

Ozone Inhalation Attenuated the Effects of Budesonide on Aspergillus fumigatus-Induced Airway Inflammation and Hyperreactivity in Mice. [PDF]

, 2019
Inhaled glucocorticoids form the mainstay of asthma treatment because of their anti-inflammatory effects in the lung. Exposure to the air pollutant ozone (O3) exacerbates chronic airways disease.
Flayer, Cameron H, Ge, Moyar Q, Haczku, Angela, Hwang, Jin W, Jiang, Zhilong, Kokalari, Blerina, Redai, Imre G   +6 more
core  

Intranasal ChAdOx1 nCoV-19/AZD1222 vaccination reduces shedding of SARS-CoV-2 D614G in rhesus macaques

bioRxiv, 2021
Intramuscular vaccination with ChAdOx1 nCoV-19/AZD1222 protected rhesus macaques against pneumonia but did not reduce shedding of SARS-CoV-2. Here we investigate whether intranasally administered ChAdOx1 nCoV-19 reduces shedding, using a SARS-CoV-2 virus
N. van Doremalen, Jyothi N. Purushotham, Jonathan E. Schulz, M. Holbrook, T. Bushmaker, A. Carmody, J. Port, C. Yinda, A. Okumura, G. Saturday, F. Amanat, F. Krammer, P. Hanley, Brian J. Smith, J. Lovaglio, S. Anzick, Kent D. Barbian, C. Martens, S. Gilbert, T. Lambe, V. Munster   +20 more
semanticscholar   +1 more source