Results 81 to 90 of about 2,213 (256)

First‐In‐Human Study of Safety, Tolerability, Efficacy, and Pharmacokinetics of CPNE7‐Derived Peptide (Selcopintide) for Dentin Hypersensitivity

open access: yesClinical and Translational Science, Volume 18, Issue 8, August 2025.
ABSTRACT Dentin hypersensitivity is characterized by transient, sharp pain resulting from dentin exposure due to enamel or cementum loss. Current treatments, which primarily focus on superficial tubule occlusion or nerve desensitization, provide only temporary relief.
Myung Jin Lee   +6 more
wiley   +1 more source

Melatonin: A Potential Therapy for Osteoporosis With Insights Into Molecular Mechanisms

open access: yesJournal of Pineal Research, Volume 77, Issue 4, July 2025.
ABSTRACT Melatonin is a versatile neurohormone with diverse molecular functions, including sleep regulation, inflammation reduction, antioxidant activity, immune modulation, and anticancer properties. In bone metabolism, it promotes osteoblast formation, inhibits osteoclast activity, and synchronizes skeletal tissue rhythms to support bone health.
Ko‐Hsiu Lu   +4 more
wiley   +1 more source

کنترل و درمان حساسيت دندانی با ليزر [PDF]

open access: yes, 2012
چکيده مقاله: مقدمه: حساسيت دندانی از شايع ‌ ترين علل مراجعه به مطب دندانپزشکی است که به درد تيز و کوتاه ناشی از عاج اکسپوز در پاسخ به تحريکات حرارتی، مکانيکی، اسموتيک و شيميايی اطلاق می ‌ شود.
حکيمی‌ها, ندا   +1 more
core  

Randomized clinical trial to evaluate changes in dentine tubule ccclusion following 4 weeks use of an occluding toothpaste [PDF]

open access: yes, 2017
Objectives: To determine whether a silicone impression material could precisely replicate dentine tubule changes following 4 weeks toothbrushing with an occluding or non-occluding toothpaste, and whether changes reflected hypersensitivity clinical ...
Claydon, Nicholas   +4 more
core   +5 more sources

Effectiveness and cytotoxicity of two desensitizing agents: a dentin permeability measurement and dentin barrier testing in vitro study

open access: yesBMC Oral Health, 2022
Background When evaluating the efficacy and safety of various desensitizing products in vitro, their mechanism of action and clinical utility should be considered during test model selection. This study aimed to evaluate the effects of two desensitizers,
Ruodan Jiang   +3 more
doaj   +1 more source

Influence of Bleaching Agents and Desensitizing Varnishes on the Water Content of Dentin

open access: yesOperative Dentistry, 2006
SUMMARY This in vitro study investigated the possible dehydration of dentin caused by bleaching agents. Furthermore, it tested whether protective dentin varnishes can maintain the physiological moisture of dentin during bleaching treatment.
Betke, Herbert   +5 more
openaire   +3 more sources

Photothermal Effect and Biomineralization of Black Phosphorus Nanosheet‐Composited Hydrogel Boosts Synergistic Treatment of Dentin Hypersensitivity (Adv. Sci. 9/2025)

open access: yesAdvanced Science, Volume 12, Issue 9, March 6, 2025.
Dentin‐Desensitized Hydrogel In article number 2412561, Congxiao Zhang, Jianxun Ding, and colleagues introduce an innovative black phosphorus nanosheet‐composited methacrylate gelatin hydrogel for treating dentin hypersensitivity. This hydrogel harnesses a synergistic photothermal effect and biomineralization to effectively occlude dentinal tubules and
Qihui Wang   +5 more
wiley   +1 more source

Efecto de NovaMin-fosfosilicato de sodio y calcio 5% y del fluoruro de sodio al 5% en la reducción de la Hipersensibilidad Dentinaria Post Terapia Periodontal. [PDF]

open access: yes, 2015
Tesis para optar al título de Cirujano-DentistaLa hipersensibilidad dentaria es un dolor breve, agudo y localizado ocasionado por estímulos térmicos, químicos, táctiles o mecánicos sobre la dentina expuesta.
Norambuena Ibarra, Javier
core  

Effectiveness of nano-calcium phosphate paste on sensitivity during and after bleaching: a randomized clinical trial

open access: yesBrazilian Oral Research, 2015
The study aimed to evaluate the effectiveness of in-office bleaching and associated tooth sensitivity on application of nano-calcium phosphate paste as desensitizing agent.
Alessandro Dourado LOGUERCIO   +4 more
doaj   +1 more source

Role of microbiota in pain: From bench to bedside

open access: yesiMetaOmics, Volume 2, Issue 1, March 2025.
Pain is closely linked to microbes. The microbiota modulates pain perception through three mechanisms: microbiota‐derived metabolites, immunoregulation, and direct stimulation on neurons. Therapeutic strategies like probiotics, fecal microbiota transplantation, and dietary changes show significant potential in pain management.
Huiguang Ren   +5 more
wiley   +1 more source

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