Results 61 to 70 of about 3,916 (178)

R‐Loops Mediated Odontogenic Differentiation of hDPSCs by Activating the cGAS‐STING Pathway Under Inflammatory Microenvironment

Oral Diseases, EarlyView.
ABSTRACT Background R‐Loops are three‐stranded DNA/RNA hybrids implicated in immune responses. Their role in mesenchymal stem cell differentiation, particularly in dental pulp regeneration under inflammation, remains unclear. Methods Rat pulpo‐dentinal complex (PDC) injury models and LPS‐stimulated human dental pulp stem cells (hDPSCs) were used.
Yun Yang, Yiqing Wang, Yating Miao, Zhipu Luo, Lin Niu, Ruirui Liu   +5 more
wiley   +1 more source

Reviewing the benefits and clinical outcomes of oral fibroblasts over mesenchymal stem cells for repairing periodontal defects during or after orthodontic tooth movement

Periodontology 2000, EarlyView.
Abstract Orthodontic therapy applies forces to teeth, causing an inflammatory reaction in the periodontal ligament. This is repaired by remodeling of the periodontium, allowing tooth displacement. Although orthodontic therapy is mostly initiated during childhood and adolescence, the number of adults seeking this treatment is increasing as our society's
Ludovica Parisi, Eleni Mavrogonatou, Anton Sculean, Dimitris Kletsas, Martin Degen   +4 more
wiley   +1 more source

Effect of Remineralization Pretreatments on Human Dentin Permeability and Bond Strength. [PDF]

Int J Dent, 2023
Abu Hasna A, Martinho FC, Sellan PLB, Pampuri CR, Torres CRG, Pucci CR.   +5 more
europepmc   +1 more source

Hyaluronic acid: A novel approach in regenerative/reconstructive periodontal therapy?

Periodontology 2000, EarlyView.
Abstract Background Although hyaluronic acid (HA) has long been used for many medical applications, only in recent years has it gained greater popularity in the field of periodontics because of its biological effects during wound healing. Even today, most clinicians are not aware that more than one type of HA exists and that the extent of its ...
Andrea Pilloni, Yoshinori Shirakata, Lorenzo Marini, Darko Božić, Richard J. Miron, Roberto Rotundo, Andreas Stavropoulos, Anton Sculean   +7 more
wiley   +1 more source

Chemical agents to control biofilm formation in step 1 of care—Toothpastes and mouthwashes/concepts and challenges

Periodontology 2000, EarlyView.
Abstract Maintaining optimal oral hygiene is important for overall oral care, ensuring the well‐being of teeth and their surrounding tissues. In addition, it promotes fresh breath and a pleasing smile. A key element of oral self‐care is the daily use of toothpaste during regular brushing.
Maud Joosstens, Cees Valkenburg, Fridus Van der Weijden   +2 more
wiley   +1 more source

Molecular Signatures of Peripheral and Central Dental Pulp Subpopulations in Response to Streptococcus mutans: A Bulk RNA‐Seq Analysis

International Endodontic Journal, Volume 59, Issue 7, Page 1402-1415, July 2026.
ABSTRACT Aim The dental pulp is an immunologically active tissue that responds dynamically to cariogenic challenge. Peripheral pulp cells adjacent to dentine encounter bacterial stimuli earlier than cells located in the central pulp. To investigate signalling and immune interactions, this study profiled the transcriptomes of dentine‐adherent cells ...
Sandra Pohl, Maximilian L. Huber, Tobias Akamp, Andreas Rosendahl, Melanie Linnebank, Lea Schreiber, Claudia Gebhard, Nicholas Strieder, Michael Rehli, Wolfgang Buchalla, Matthias Widbiller   +10 more
wiley   +1 more source

Comparison of Dentin Permeability After Tooth Cavity Preparation with Diamond Bur and Er:YAG Laser

Frontiers in Dentistry, 2016
Objectives: The aim of this study was to compare the permeability of dentin after using diamond bur and Er:YAG laser. Materials and Methods: Seventy-two recently extracted, intact, and restoration-free human permanent molars were used in this study. The
Masoumeh Hasani Tabatabaei, Sara Shirmohammadi, Esmaeil Yasini, Mansoureh Mirzaei, Sakineh Arami, Hamid Kermanshah, Ladan Ranjbar Omrani, Azar Alimi, Nasim Chiniforush, Afrooz Nakhostin, Mahdi Abbasi   +10 more
doaj  

Comparative Evaluation of Penetration of Two Irrigating Solutions into Dentinal Tubules Using Diode Laser and Ultrasonic Activation: A Confocal Laser Microscopy Study Protocol [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Endodontic therapy aims to eradicate pulpal and periapical diseases by removing bacteria from root canals. Despite thorough cleaning, the smear layer obstructs canal disinfection.
Palak Hirani, Manoj Chandak
doaj   +1 more source

Diagnostic Accuracy of Dentin Sclerosis by Optical Coherence Tomography and the North Carolina Index in Noncarious Cervical Lesions

Journal of Esthetic and Restorative Dentistry, Volume 38, Issue 7, Page 1435-1447, July 2026.
ABSTRACT Objective To evaluate the diagnostic accuracy of optical coherence tomography (OCT) and the North Carolina Index (NCI) for identifying dentin type (sclerotic vs. nonsclerotic) in natural noncarious cervical lesions (NCCLs). Materials and Methods Thirty extracted human premolars with 30 NCCLs (90 regions of interest) were analyzed. Two blinded,
Nathalie Murielly Rolim de Abreu, Rudyard dos Santos Oliveira, Anauara Lima e Silva, Laryssa Mylenna Madruga Barbosa, Alessandro Dourado Loguercio, Frederico Barbosa de Sousa   +5 more
wiley   +1 more source

Novel Chlorhexidine-Loaded Polymeric Nanoparticles for Root Canal Treatment

Journal of Functional Biomaterials, 2018
Persistence of microorganisms in dentinal tubules after root canal chemo-mechanical preparation has been well documented. The complex anatomy of the root canal and dentinal buffering ability make delivery of antimicrobial agents difficult.
Gina Quiram, Francisco Montagner, Kelli L. Palmer, Mihaela C. Stefan, Katherine E. Washington, Danieli C. Rodrigues   +5 more
doaj   +1 more source