Results 51 to 60 of about 2,474 (180)

Clinical and Molecular Heterogeneity Underlying Monogenic Causes of Pediatric Diabetes Associated to Brain Developmental Disorders

Clinical Genetics, Volume 108, Issue 5, Page 495-510, November 2025.
A growing number of genetic variants linking non‐autoimmune diabetes to NDDs across different ages offer key insights about a common background of these phenotypes. These findings call for multidisciplinary approaches to care that integrate metabolic and neurological management in affected children.
Gabriele Di Pasquale, Camilla Valsecchi, Giulia Marie Smylie, Vincenzo Salpietro, Gian Vincenzo Zuccotti, Maurizio Delvecchio, Chiara Mameli   +6 more
wiley   +1 more source

Pediatric Scoliosis in Osteogenesis Imperfecta: From Genetic Mechanisms to Therapeutic Strategies

Orthopaedic Surgery, Volume 17, Issue 11, Page 3036-3047, November 2025.
This review explores the genetic underpinnings and treatment strategies for spinal deformities in children with osteogenesis imperfecta. Emphasis is placed on emerging molecular insights and modern surgical techniques that improve the management of severe scoliosis and enhance patient outcomes.
Vladislav Muldiiarov, Keely Buesing, Maegen J. Wallace   +2 more
wiley   +1 more source

Immunocytochemical detection of dentin matrix proteins in primary teeth from patients with dentinogenesis imperfecta associated with osteogenesis imperfecta

European Journal of Histochemistry, 2014
Dentinogenesis imperfecta determines structural alterations of the collagen structure still not completely elucidated. Immunohistochemical analysis was used to assay Type I and VI collagen, various non-collagenous proteins distribution in human primary ...
G. Orsini, A. Majorana, A. Mazzoni, A. Putignano, M. Falconi, A. Polimeni, L. Breschi   +6 more
doaj   +1 more source

Dentofacial Features in Schimke Immuno‐Osseous Dysplasia: From Childhood to Adolescence

Clinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT Schimke immune‐osseous dysplasia (SIOD) is a sporadic multi‐system disorder mainly characterized by spondyloepiphyseal dysplasia, immune insufficiency, and renal failure. Little evidence is available regarding the dentofacial features of SIOD.
Alireza Sharifinejad, Fateme Parvizi, Maryam Enteghad, Yasamin Ghahramani   +3 more
wiley   +1 more source

Clinical Features of Osteogenesis Imperfecta in Taiwan

Journal of the Formosan Medical Association, 2009
Osteogenesis imperfecta (OI) (MIM 166200, 166210, 259420 and 166220) is a congenital disorder characterized by increased bone fragility and low bone mass. Information regarding the clinical features of this genetic disorder is lacking in Taiwan.
Hsiang-Yu Lin, Shuan-Pei Lin, Chih-Kuang Chuang, Ming-Ren Chen, Chia-Ying Chang, Dau-Ming Niu   +5 more
doaj   +1 more source

Penicillin Disrupts Dental Mineralization in Rats: A Comparative Study With Tetracycline Highlighting Prenatal and Postnatal Risks

Clinical and Experimental Dental Research, Volume 11, Issue 5, October 2025.
ABSTRACT Objectives Penicillin's impact on enamel defects remains understudied, particularly regarding its ability to cause structural issues even at therapeutic doses. Material and Methods Pregnant Wistar rats received daily gavage from gestational day 13–22 with saline (control), 130 mg/kg tetracycline, 50 mg/kg penicillin, or 100 mg/kg penicillin ...
Sedigheh Mozafar, Fateme Mashhadi Abbas, Majid Mehran, Somayeh Kameli, Motahare Ahmadvand, Amir Mohammad Sharafi, Reza Omid, Morteza Banakar   +7 more
wiley   +1 more source

ISOLATED DENTINOGENESIS IMPERFECTA AND IN ASSOCIATION WITH OSTEOGENESIS IMPERFECTA – A LITERATURE REVIEW [PDF]

Romanian Medical Journal, 2018
Dental development is part of the craniofacial organogenesis, starting from the pluripotent cephalic neural crest cells, continuing with their movement towards the first pharyngeal arch and leading to the development of many elements of the ...
Andrei Kozma, Doriana Agop Forna, Viorica Radoi, Ana Maria Alexandra Stanescu, Radu Ursu, Laurentiu Camil Bohaltea   +5 more
doaj   +1 more source

Evaluation of Fractal and Radiomorphometric Measurements of Mandibular Bone Structure in Pediatric Patients With Molar Incisor Hypomineralization

International Journal of Paediatric Dentistry, Volume 35, Issue 5, Page 945-953, September 2025.
ABSTRACT Background Molar incisor hypomineralization (MIH) is associated with enamel's existing qualitative developmental defects. Aim This study aimed to assess the cortical and trabecular mandibular bone morphology in pediatric patients with MIH using fractal analysis (FA) and digital panoramic radiography (DPR) with various radiomorphometric indices.
Asli Soğukpinar Önsüren, Katibe Tugce Temur   +1 more
wiley   +1 more source

Dental Hard Tissue Study In A Hereditary Dentinogenesis Imperfecta Family

International Dental Journal
Aim or purpose: Hereditary dentinogenesis imperfecta is a rare autosomal dominant genetic disorder characterized by abnormal dentin structure, leading to impaired dental function and aesthetics.
Zhongren Deng, Yue Ning, Qin Du
doaj   +1 more source

Quality of Vertical Bitewings Radiographs and Common Errors of Positioning in Children

International Journal of Paediatric Dentistry, Volume 35, Issue 4, Page 869-875, July 2025.
ABSTRACT Background Vertical bitewing radiographs (VBWs) are often used in paediatric dentistry but no clinical studies have been conducted to evaluate the feasibility or effectiveness of their use. Hypothesis/Aim To evaluate the quality of VBWs taken in children by undergraduate dental students.
Isabel C. Olegário, Rona Leith, Anne C. O'Connell   +2 more
wiley   +1 more source