Results 211 to 220 of about 584,020 (297)

From anthelmintic to neuro‐oncology: A systematic review of mebendazole repurposing for brain tumour therapy

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Mebendazole (MBZ), a benzimidazole anthelmintic with established clinical use, has emerged as a repurposing candidate for primary brain tumours due to its multimodal anticancer actions and central nervous system penetrance. This systematic review synthesizes preclinical and clinical evidence evaluating MBZ's efficacy, mechanisms of action ...
Ciara B. Blum, Milli McMenamin, Tessa Khoo, John M. Edwin, Prathibha Jose, Liam A. O’Callaghan   +5 more
wiley   +1 more source

Understanding the Content and Purpose of S3 Clinical Practice Guidelines in Dentistry. [PDF]

Int Endod J
Schwendicke F, Kosan E, Banerjee A, Baysan A, Bjørndal L, Ceballos L, Duncan HF, Herbst S, Neuhaus KW, O'Connell AC, Paris S, Dujic H.   +11 more
europepmc   +1 more source

Metabolomic investigation of cisplatin‐induced acute kidney injury in paediatric cancer patients

British Journal of Clinical Pharmacology, EarlyView.
Aim Cisplatin causes acute kidney injury (AKI) in approximately 46% of paediatric cancer patients who receive it. Serum creatinine (SCr) is a poor biomarker of cisplatin nephrotoxicity, because there is a delay between cisplatin infusion and SCr elevation.
Yong Jin Lim, Amy Thachil, Kelly McMahon, Ross T. Tsuyuki, S. Rod Rassekh, Lesley G. Mitchell, Prasad Devarajan, Cherry Mammen, Bruce C. Carleton, Geoffrey D. E. Cuvelier, Victor A. Lewis, Colin J. D. Ross, Alexandra P. Zorzi, Sylvain Baruchel, Raveena Ramphal, Eric Bouffet, Mathieu Lemaire, Tom D. Blydt‐Hansen, Brad L. Urquhart, The Applying Biomarkers to Minimize Long‐Term Effects of Childhood/Adolescent Cancer Treatment (ABLE) Research Study Group, Tom Blydt‐Hansen, Bruce C. Carleton, Geoff D. E. Cuvelier, Sunil Desai, Prasad Devarajan, Conrad Fernandez, Adam Fleming, Paul Gibson, Caroline Laverdiere, Victor Lewis, Mary L. McBride, Bruno Michon, Shahrad Rod Rassekh, Colin J. D. Ross, Christine Sabapathy, Kirk R. Schultz, Michael Zappitelli, Alexandra Zorzi   +37 more
wiley   +1 more source

Beyond Algorithms: Embodied Artificial Intelligence and the Future of Dentistry. [PDF]

Int Dent J
Turky M, Dummer PMH.
europepmc   +1 more source

Histamine and the mechanisms of nausea and vomiting: Translating the uncertain pharmacology of cyclizine

British Journal of Clinical Pharmacology, EarlyView.
Abstract Cyclizine is a long‐established, short‐acting drug, registered for preventing motion sickness, post‐operative nausea and vomiting (PONV) and ‘vomiting of known cause’. The latter is not defined but may include pregnancy and patients receiving palliative care, historically accepted without large, controlled trials.
Gareth J. Sanger, Paul L. R. Andrews
wiley   +1 more source

Operative dentistry

, 1981
藤井, 弁次, 1929-, 片山, 伊九右衛門, 1930-   +1 more
openaire   +1 more source

Selective Caries Removal as a Restorative Strategy for Caries Management: Residual Dentin Quality After Chemomechanical and Mechanical Excavation. [PDF]

Dent J (Basel)
Ramirez-Martinez GG, Lopez-Ayuso CA, Scougall-Vilchis RJ, Rojas-Rueda S, Jurado CA, Alshabib A, Nurrohman H, Garcia-Contreras R.   +7 more
europepmc   +1 more source

The placental transfer of nirmatrelvir using the ex vivo human placental perfusion model

British Journal of Clinical Pharmacology, EarlyView.
Aims Nirmatrelvir is an effective therapeutic option for COVID‐19 infection and is often administered after symptom onset in pregnant individuals, but few data are available on the associated fetal exposure. The placental perfusion model evaluates maternal–fetal drug transfer across the human placenta and thus can determine fetal drug exposure.
Magdalene Zabek, Eddie Chan, Yong Jin Lim, Bradley L. Urquhart, Facundo Garcia‐Bournissen, Janine R. Hutson   +5 more
wiley   +1 more source

Direct composite injection molding with bilayered three-dimensional-printed clear index: a fully digital workflow case report of post-orthodontic anterior tooth wear. [PDF]

Restor Dent Endod
Utsumi Y, Tagami J, Loomans B, Scotti N, Watanabe K, Matsuki S, Tanaka E, Hosaka K.   +7 more
europepmc   +1 more source