Results 81 to 90 of about 39,975 (293)

Generation of Self‐Organizing Macrovascular Constructs by Bioprinting Human iPSC‐Derived Mesodermal Progenitor Cells

open access: yesAdvanced Science, EarlyView.
ABSTRACT Vascularization remains a major obstacle in tissue engineering. Here, we introduce a bioprinting strategy to generate centimeter‐scale, self‐organizing “mother vessel” constructs from iPSC‐derived hiMPCs. By optimizing bioink composition, printing was accomplished in a single‐step approach. Within one week, hiMPCs differentiated into both CD31+
Leyla E. Dogan   +5 more
wiley   +1 more source

Nanofilled Resin Composite Properties and Clinical Performance: A Review

open access: yes, 2018
SUMMARY The aim of this review was to compile recent evidence related to nanofilled resin composite materials regarding the properties and clinical performance.
H Alzraikat   +7 more
core   +1 more source

Spatiotemporal Targeting Randle Cycle and Immune Checkpoint for Potent Antitumor Therapy

open access: yesAdvanced Science, EarlyView.
A glucose oxidase‐based nanogel (GOX‐NG) system using catechol‐functionalized alginate, exhibits enhanced tumor penetration, prolonged retention, and sustained glucose depletion in the tumor microenvironment. When combined with a fatty acid oxidation inhibitor, it implements dual metabolic suppression, thereby enhancing ROS‐induced immunogenic cell ...
Yuan Gao   +11 more
wiley   +1 more source

Post retention strength of apical and conventional coating obturation methods using bioceramic sealer: a laboratory investigation

open access: yesBMC Oral Health
Background Once bioceramic sealer (BCS) enters the dentinal tubules, it cannot be reliably removed. BCS-occupied dentinal tubules reduce fibre post retention strength.
Benjarat Chanapairin   +2 more
doaj   +1 more source

Accuracy of Ceramic Restorations Made Using an In-office Optical Scanning Technique: An In Vitro Study

open access: yes, 2014
The present in vitro study concerns determination of the pre-cementation gap width of all-ceramic crowns made using an in-office digital-impression technique and subsequent computer-aided design/computer-aided manufacturing (CAD/CAM) production.
K Ottosson   +5 more
core   +1 more source

EpCAM+ Extracellular Vesicle PD‐L1 Dynamics as a Predictive Biomarker of Immune Checkpoint Blockade Response

open access: yesAdvanced Science, EarlyView.
A highly sensitive SERS‐based platform measures PD‐L1 expression on EpCAM+ circulating EVs from cancer patients undergoing immunotherapy. Monitoring dynamic changes after treatment reveals that reduced EpCAM+ EV PD‐L1 levels associate with improved long‐term clinical outcomes, establishing a non‐invasive approach for tracking immune checkpoint ...
Byeonggeol Mun   +15 more
wiley   +1 more source

Long-term influence of applied dentin sealing techniques and luting material type on the bond durability of a resin CAD/CAM restorative material

open access: yesBMC Oral Health
Background The durability of bonded CAD/CAM restorations depends largely on effective adhesion to dentin. Immediate dentin sealing (IDS) has been proposed to enhance bonding effectiveness compared with conventional delayed dentin sealing (DDS ...
Ghadeer Abo-Eldahab   +2 more
doaj   +1 more source

Smart Denture with Embedded Thin‐Film Temperature Sensors Patterned by Femtosecond Laser Pulse for Elderly Healthcare

open access: yesAdvanced Intelligent Systems, Volume 7, Issue 3, March 2025.
We demonstrate the direct‐laser patterning of a gold thin film on polymethyl methacrylate to fabricate a temperature sensor for dentures. The temperature sensor‐embedded smart dentures are evaluated in an oral environment, enabling in‐situ monitoring for elderly healthcare.
Han Ku Nam   +7 more
wiley   +1 more source

Evaluating flexure properties, hardness, roughness and microleakage of high-strength injectable dental composite: an in vitro study

open access: yesBMC Oral Health
Background Recently, a new generation of high-strength flowable dental composites has been introduced by manufacturers. The manufacturers claim that these materials have enhanced mechanical and physical properties and are suitable for use in a wide range
Rasha R. Basheer   +2 more
doaj   +1 more source

Human Leukocyte Elastase Triggered Nanoparticles for Targeted Antimicrobial Delivery and Oral Microbial Modulation

open access: yesAdvanced NanoBiomed Research, EarlyView.
This study explores enzyme‐responsive nanoparticles for targeted antimicrobial release in inflamed oral environments. Nanoparticles formed by complexing peptides and chlorhexidine respond to human leukocyte elastase and release chlorhexidine selectively. P7 (ECAAPVCE)‐based formulations show optimal properties and stability, with antimicrobial activity
Mohammed A. Hadis   +9 more
wiley   +1 more source

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