Results 121 to 130 of about 802,826 (313)

NUAK2 Inhibition Enhances Macromolecular Drug Delivery in a 3D Fibrotic Model of the Pancreatic Tumor Microenvironment

Advanced NanoBiomed Research, EarlyView.
Using a 3D cell culture model of the fibrotic barrier in pancreatic cancer, this work shows that inhibiting NUAK2 kinase in pancreatic stellate cells enhances macromolecular drug delivery. Mechanistically, NUAK2 inhibition disrupted actin stress fiber assembly to downregulate collagen I expression, thus enhancing macromolecular permeability.
Misaki Nakamura, Hiroyoshi Y. Tanaka, Mayu Ohira, Haruko Ohta‐Okano, Reika Nakamura, Yu Seno, Saaya Yara, Sakura Fujita, Daichi Shibata, Masaya Yamamoto, Shinichi Toyooka, Kensuke Osada, Horacio Cabral, Atsushi Masamune, Mitsunobu R. Kano   +14 more
wiley   +1 more source

Visualization of oral function during playing a wind instrument by a lateral dental impression: a proof-of-concept investigation

Frontiers in Oral Health
Embouchure describes the interaction of the teeth, lips, tongue, buccal mucosa, and surrounding muscles when playing woodwind and brass instruments. In dental practice, impression material is used to capture the oral structure and function. In this proof-
Mariko Hattori, Gen Tanabe, Sebastian B. M. Patzelt, Sebastian B. M. Patzelt, Dirk Schulze, Yuka I. Sumita, Noriyuki Wakabayashi   +6 more
doaj   +1 more source

Differences in Utilization of Dental Procedures by Children Enrolled in Wisconsin Medicaid And Delta Dental Insurance Plans [PDF]

, 2016
Background Few studies have directly compared dental procedures provided in public and private insurance plans for enrollees living in dental health professional shortage areas (DHPSAs).
Bhagavatula, Pradeep, Eichmiller, Fredrick, Okunseri, Christopher, Szabo, Aniko, Xiang, Qun   +4 more
core   +1 more source

Multimaterial Triphasic Scaffold Replicates Enthesis Microenvironment to Modulate Early Cell Responses

Advanced NanoBiomed Research, EarlyView.
A bioinspired triphasic scaffold integrating 3D printed polycaprolactone and electrospun poly(lactic‐co‐glycolic acid) is developed to replicate the organization of the tendon‐to‐bone enthesis. Cyclic mechanical stimulation induces spatially defined cell morphology and lineage‐related gene expression in human mesenchymal stem cells, highlighting the ...
Ginevra Pegollo, Simone Micalizzi, Girish Pattappa, Philipp Stahlhut, Jürgen Groll, Carmelo De Maria, Denitsa Docheva, Giovanni Vozzi   +7 more
wiley   +1 more source

Retracted: Primary Small Cell Undifferentiated (Neuroendocrine) Carcinoma of the Maxillary Sinus

Case Reports in Dentistry, 2014
Case Reports in Dentistry
doaj   +1 more source

Human Leukocyte Elastase Triggered Nanoparticles for Targeted Antimicrobial Delivery and Oral Microbial Modulation

Advanced NanoBiomed Research, EarlyView.
This study explores enzyme‐responsive nanoparticles for targeted antimicrobial release in inflamed oral environments. Nanoparticles formed by complexing peptides and chlorhexidine respond to human leukocyte elastase and release chlorhexidine selectively. P7 (ECAAPVCE)‐based formulations show optimal properties and stability, with antimicrobial activity
Mohammed A. Hadis, Ignacio Insua, Farah N. S. Raja, Álvaro Vila, William M. Palin, Michael R. Milward, Paul R. Cooper, Sarah A. Kuehne, Owen Addison, Paco Fernandez‐Trillo   +9 more
wiley   +1 more source

Retracted: A Rare Pathological Entity of Multiple Calcified Hyperplastic Dental Follicles

Case Reports in Dentistry, 2017
Case Reports in Dentistry
doaj   +1 more source

Direct Oral Anticoagulants and Bleeding Management Following Tooth Extractions—A Prospective Cohort Study

Dentistry Journal
The aim of the present study was to assess the occurrence of intra-, peri-, and post-operative bleeding following tooth extractions in patients treated with direct oral anticoagulants (DOACs). Consecutive patients requiring at least one dental extraction
Rossana Izzetti, Chiara Cinquini, Marco Nisi, Marco Mattiozzi, Monica Marotta, Antonio Barone   +5 more
doaj   +1 more source

Injectable Bone Cements: A Generational Framework for Bioactivity, Porosity, and Mechanobiological Design at the Nanoscale

Advanced NanoBiomed Research, EarlyView.
Key demographic, biological, and material considerations that drive the need for advanced injectable bone cement technologies. Injectable bone cements (IBCs) are widely used in orthopaedic and craniofacial applications due to their minimally invasive delivery and ability to provide early mechanical stabilisation.
Frank Fei, Yogambha Ramaswamy, Young Jung No   +2 more
wiley   +1 more source

Preemptive oral analgesia with steroidal and nonsteroidal anti-inflammatory drugs in periodontal surgery: a systematic review

Frontiers in Pharmacology
Introduction: Periodontal procedures can promote prolonged intense pain, particularly in clinical situations requiring surgical procedures. In this context, preemptive analgesia has also been assessed for its utility in controlling post-operative pain ...
Lívio Portela de Deus Lages, Cristiane de Cássia Bergamaschi, Luciane Cruz Lopes, Eduardo Gomes da Frota, Marcus Tolentino Silva, Thiago Lima Monte, Rogério Heládio Lopes Motta   +6 more
doaj   +1 more source