Results 181 to 190 of about 573,677 (352)

The Spectrum of Neurologic Phenotypes Associated With NUS1 Pathogenic Variants: A Comprehensive Case Series

open access: yesAnnals of Neurology, EarlyView.
Objective A growing body of evidence indicates a strong genetic overlap between developmental and epileptic encephalopathies (DEEs) and movement disorders. De novo loss‐of‐function variants in NUS1 have been recently identified in DEE cases. Herein, we report a large cohort of cases with pathogenic NUS1 variants and describe their clinical presentation
Sarah M. Brooker   +79 more
wiley   +1 more source

μ‐Opioid Receptor Dynamics in the Parameningeal Tissue During Migraine Attacks

open access: yesAnnals of Neurology, EarlyView.
Objective The possible impact of meningeal μ‐opioid receptor (μOR) binding in migraine remains unknown. This study investigated μOR availability in the cranial parameninges involved in migraine initiation via nociceptor activation. Methods We used positron emission tomography with [11C] carfentanil, and measured μOR availability in meninges and ...
Dajung J. Kim   +6 more
wiley   +1 more source

Sex Differences in Associations of Lewy Body Disease with Alzheimer's Disease and Cognitive Decline

open access: yesAnnals of Neurology, EarlyView.
Objective To investigate how sex and age at menopause influence the interplay between Alzheimer's disease (AD) and Lewy body disease (LBD) neuropathologies, and their associations with cognitive decline. Methods We analyzed data from: (1) three Rush Alzheimer's Disease Center cohorts (i.e., the Religious Orders Study, Rush Memory and Aging Project, and
Madeline Wood Alexander   +17 more
wiley   +1 more source

Acceptance and readiness for tele-dentistry among dental professionals amidst conflict in Sudan. [PDF]

open access: yesBMC Oral Health
Alabass SO   +10 more
europepmc   +1 more source

Heart Rate Profiles During Exercise and Incident Parkinson's Disease

open access: yesAnnals of Neurology, EarlyView.
Objective To determine whether established heart rate parameters of exercise, related to cardiac autonomic function, are associated with incident Parkinson's disease, independent of both clinical and autonomic prodromal features. Methods A study of UK Biobank participants who performed a standardized bicycle exercise test (2009–2013), followed until ...
Stefan van Duijvenboden   +13 more
wiley   +1 more source

Cationic Nanoparticles Mitigate Chemotherapy‐Induced Peripheral Neuropathy

open access: yesAdvanced NanoBiomed Research, EarlyView.
Chemotherapy‐induced peripheral neuropathy (CIPN), caused by chemodrugs like paclitaxel (PTX), leads to severe neuropathic pain. This study evaluates PTX‐loaded PAMAM‐Chol nanoparticles (PTX‐NPs) to alleviate CIPN. PTX‐NPs achieve 99% drug‐loading efficiency, reduce neurotoxicity, and in murine models, decrease cold allodynia by 85% while restoring ...
Divya Bhansali   +7 more
wiley   +1 more source

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