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DENV-1 genotype V linked to the 2022 dengue epidemic in Southern Brazil

Journal of Clinical Virology, 2023
Even though Brazil is a country where the dengue virus (DENV) is endemic, until recently, Southern states did not have significant viral circulation, such as Rio Grande do Sul (RS), and some municipalities were even considered dengue-free. During 2022, these places have shown a sharp increase in the incidence of the disease, apparently following a ...
Juliana Schons Gularte   +12 more
openaire   +2 more sources

Genetic diversity and spatiotemporal dynamics of DENV-1 and DENV-2 infections during the 2012–2013 outbreak in Mexico

Virology, 2022
Dengue fever is caused by four related dengue virus serotypes, DENV-1 to DENV-4, where each serotype comprises distinct genotypes and lineages. The last major outbreak in Mexico occurred during 2012 and 2013, when 112,698 confirmed cases were reported (DENV-1 and DENV-2 were predominant).
Eduardo D. Rodríguez-Aguilar   +5 more
openaire   +2 more sources

Genotypic variability analysis of DENV-1 in Mexico reveals the presence of a novel Mexican lineage

Archives of Virology, 2018
Here, we report for the first time the circulation of dengue virus type 1 (DENV-1) belonging to the lineage IV of genotype V (African American genotype) based on phylogenetic analysis of nucleotide sequences from 10 DENV-1-positive samples obtained in Mexico between 2012 and 2014. Our data revealed that the lineages III and IV of DENV-1 genotype V were
Elizabeth, González-Durán   +14 more
openaire   +2 more sources

Generation and preclinical evaluation of a DENV-1/2 prM+E chimeric live attenuated vaccine candidate with enhanced prM cleavage

Vaccine, 2013
In the absence of a vaccine or sustainable vector control measures, illnesses caused by dengue virus infection remain an important public health problem in many tropical countries. During the export of dengue virus particles, furin-mediated cleavage of the prM envelope protein is usually incomplete, thus generating a mixture of immature, partially ...
Poonsook, Keelapang   +9 more
openaire   +2 more sources

Severe dengue due to secondary DENV-1 infection in Mainland China

Journal of Clinical Virology, 2013
Wen-Xin Hong   +13 more
openaire   +1 more source

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