Results 11 to 20 of about 93,300,230 (204)

Concurrent infection with dengue virus type-2 and DENV-3 in a patient from Ceará, Brazil [PDF]

Memorias do Instituto Oswaldo Cruz, 2006
Dengue outbreaks have occurred in several regions in Brazil and cocirculating dengue virus type 1 (DENV-1), DENV-2, and DENV-3 have been frequently observed.
Fernanda Montenegro de Carvalho Araújo, Rita Maria Ribeiro Nogueira, Josélio Maria Galvão de Araújo, Izabel Letícia Cavalcante Ramalho, Maria Lucia Feitosa de Sá Roriz, Maria Elizabeth Lisboa de Melo, Ivo Castelo Branco Coelho   +6 more
doaj   +5 more sources

Differential heterologous neutralisation profile against strains within DENV-3 genotype II. [PDF]

Epidemiol Infect, 2021
Abstract The dengue virus type 3 (DENV-3) homotypic outbreak cycles reported in Klang Valley, Malaysia in 1992–1995 and 2002 demonstrated different epidemic magnitude and duration. These outbreak cycles were caused by two closely related strains of viruses within the DENV-3 genotype II (DENV-3/II).
Tan KK, Abubakar S.
europepmc   +6 more sources

Computational prediction and analysis of envelop glycoprotein epitopes of DENV-2 and DENV-3 Pakistani isolates: a first step towards Dengue vaccine development.

PLoS ONE, 2015
Dengue fever of tropics is a mosquito transmitted devastating disease caused by dengue virus (DENV). There is no effective vaccine available, so far, against any of its four serotypes (DENV-1, DENV-2, DENV-3, and DENV-4).
Hafsa Amat-ur-Rasool, Anam Saghir, Muhammad Idrees   +2 more
doaj   +2 more sources

Autochthonous spread of DENV-3 genotype III in Malaysia mitigated by pre-existing homotypic and heterotypic immunity [PDF]

Epidemiology and Infection, 2018
AbstractDengue virus type 3 genotype III (DENV-3/III) is widely distributed in most dengue-endemic regions. It emerged in Malaysia in 2008 and autochthonously spread in the midst of endemic DENV-3/I circulation. The spread, however, was limited and the virus did not cause any major outbreak.
K. K. Tan, S. Nellis, N. I. Zulkifle, S. Sulaiman, S. AbuBakar   +4 more
core   +5 more sources

Dengue in Fiji: epidemiology of the 2014 DENV-3 outbreak. [PDF]

Western Pac Surveill Response J, 2019
Dengue virus serotype-3 caused a large community-level outbreak in Fiji in 2013 and 2014. We aimed to characterize the demographic features of affected individuals and to determine dengue mortality during the outbreak.All laboratory-confirmed dengue cases and deaths were included in this study.
Getahun A, Batikawai A, Nand D, Khan S, Sahukhan A, Faktaufon D.   +5 more
europepmc   +5 more sources

Viral Dynamic Model-Informed Dose Selection of Mosnodenvir Prophylaxis against DENV-3 in a Controlled Human Infection Model. [PDF]

Clin Pharmacol Ther
Dengue virus (DENV) infection is a significant global health threat. Mosnodenvir (JNJ‐64281802) is a pan‐serotype small molecule antiviral blocking DENV replication. A Phase IIa study (NCT05048875) evaluated the antiviral activity, safety, and pharmacokinetics of mosnodenvir as prophylaxis against DENV‐3 in a controlled human infection model (CHIM).
Goeyvaerts N, de Trixhe XW, Neyens M, Kakuda TN, Van Wesenbeeck L, Buelens A, Rasschaert F, Durbin A, Ackaert O.   +8 more
europepmc   +2 more sources

Comparative phylogenetic analysis and transcriptomic profiling of Dengue (DENV-3 genotype I) outbreak in 2021 in Bangladesh. [PDF]

Virol J, 2023
Abstract Background The next-generation sequencing (NGS) technology facilitates in-depth study of host-pathogen metatranscriptome. We, therefore, implicated phylodynamic and transcriptomic approaches through NGS technology to know/understand the dengue virus (DENV) origin and host response with
Sarkar MMH, Rahman MS, Islam MR, Rahman A, Islam MS, Banu TA, Akter S, Goswami B, Jahan I, Habib MA, Uddin MM, Mia MZ, Miah MI, Shaikh AA, Khan MS.   +14 more
europepmc   +4 more sources

Re-emergence of DENV-3 in Paraguay after two decades: a genomic and epidemiological investigation. [PDF]

Emerg Microbes Infect
We report the re-emergence of dengue virus serotype 3 (DENV-3) in Paraguay after 15 years of absence. Twelve laboratory-confirmed cases were detected in early 2025 in the Asunción metropolitan region. Genomic sequencing identified DENV-3 genotype III, lineage B.3.2, indicating a new introduction of an emerging lineage rather than renewed local ...
Cantero C, Vazquez C, Gonzalez S, Rojas A, Fleitas F, Barrios J, Gomez De La Fuente A, Villalba S, Torales M, Ijeda A, Fonseca V, Junior Alcantara LC, Giovanetti M.   +12 more
europepmc   +4 more sources

Homotypic antibodies target novel E glycoprotein domains after natural DENV 3 infection/vaccination. [PDF]

Cell Host Microbe, 2023
The envelope (E) glycoprotein is the primary target of type-specific (TS) neutralizing antibodies (nAbs) after infection with any of the four distinct dengue virus serotypes (DENV1–4). nAbs can be elicited to distinct structural E domains (EDs) I, II, or III. However, the relative contribution of these domain-specific antibodies is unclear. To identify
Munt JE, Henein S, Adams C, Young E, Hou YJ, Conrad H, Zhu D, Dong S, Kose N, Yount B, Meganck RM, Tse LPV, Kuan G, Balmaseda A, Ricciardi MJ, Watkins DI, Crowe JE, Harris E, DeSilva AM, Baric RS.   +19 more
europepmc   +3 more sources

Circulation of DENV-3 Genotype 3 during 2017 to 2018 in Delhi: A Single-Center Hospital-Based Study. [PDF]

J Lab Physicians, 2022
Abstract Introduction Delhi is hyperendemic for dengue virus (DENV) where all the four DENV have previously been reported. A constant vigilance of circulating DENV serotypes is important in surveillance, since the introduction of a new variant to areas affected by preexisting serotypes constitutes a risk factor for dengue hemorrhagic ...
Padhi A, Gupta E, Singh G, Parveen S, Islam A, Tarai B.   +5 more
europepmc   +4 more sources