Which Predictor, SctO2 or SstO2, Is more Sensitive for Postoperative Cognitive Dysfunction in Spine Surgery: A Prospective Observational Study? [PDF]
The patients with postoperative cognitive dysfunction (POCD) had a higher decrease in intraoperative absolute somatic tissue oxygen saturation (SstO2) decrease (4.9 ± 3.8 vs 3.6 ± 2.6, P = 0.037) (A) and a higher decrease in intraoperative relative SstO2 decrease (7.4 ± 5.6 vs 5.3 ± 3.8, P = 0.036) (B). The proportion below 90% of baseline SstO2 in the
Guo F +9 more
europepmc +2 more sources
Effect of Goal-Directed Fluid Therapy on Hypotension From Spinal Anesthesia in Older Parturients Having Cesarean Section: A Randomized Controlled Trial. [PDF]
Background The proportion of advanced maternal age (AMA) parturients in China has gradually increased. AMA is considered a risk factor for adverse maternal and fetal outcomes. Goal‐directed fluid therapy (GDFT) was used to guide perioperative volume management in order to reduce spinal anesthesia‐induced hypotension and optimize maternal and infant ...
Ni J +7 more
europepmc +2 more sources
Effects of repeated short episodes of environmental acidification on Atlantic salmon (Salmo salar) from a landlocked population [PDF]
Chronic or repeated exposure to environmental contaminants may result in allostatic overload, a physiological situation in which the costs of coping affect long-term survival and reproductive output.
Haraldstad, Tormod +5 more
core +3 more sources
Increasing the dietary n-6/n-3 ratio alters the hepatic eicosanoid production after acute stress in Atlantic salmon (Salmo salar) [PDF]
Earlier studies have indicated that a high inclusion of n-6 fatty acids (FA) in feeds for Atlantic salmon can affect the stress response. To test this hypothesis, Atlantic salmon (Salmo salar) were fed diets containing varying dietary n-6/n-3 FA ratios ...
Araujo, Pedro +6 more
core +2 more sources
Stereoselectivity in Drug Membrane Transport by Solute Carriers (SLCs) [PDF]
Deutsche Forschungsgemeinschaft (DFG - project number 437446827)About 50% of all small molecule drugs are racemic mixtures of usually two stereoisomers.
Gebauer, Lukas
core +1 more source
The Impact of Fentanyl on the Effective Dose of Remimazolam-Induced Sedation in Elderly Female Patients: An Up-and-Down Sequential Allocation Trial. [PDF]
Xiao-Dong Huang,1,* Jia-Bao Chen,2,* Xiao-Yun Dong,1 Wei-Long Wang,1 Jin Zhou,1 Zhen-Feng Zhou1 1Department of Anesthesiology, Hangzhou Women’s Hospital (Hangzhou Maternity and Child Health Care Hospital, Hangzhou First People’s Hospital ...
Huang XD +5 more
europepmc +3 more sources
Effects of HIV/TAT protein expression and chronic selegiline treatment on spatial memory, reversal learning and neurotransmitter levels in mice [PDF]
Neurotoxic viral protein TAT may contribute to deficits in dopaminergic and cognitive function in individuals infected with human immunodeficiency virus.
Group, TMARC +3 more
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Coping with unpredictability: Dopaminergic and neurotrophic responses to omission of expected reward in Atlantic salmon (Salmo salar L.). [PDF]
Comparative studies are imperative for understanding the evolution of adaptive neurobiological processes such as neural plasticity, cognition, and emotion.
A Alcaro +81 more
core +6 more sources
Transient activation of dopaminergic neurons during development modulates visual responsiveness, locomotion and brain activity in a dopamine ontogeny model of schizophrenia [PDF]
It has been observed that certain developmental environmental risk factors for schizophrenia when modeled in rodents alter the trajectory of dopaminergic development, leading to persistent behavioural changes in adults. This has recently been articulated
A Gonzalo-Gomez +55 more
core +1 more source
Adult vitamin D deficiency leads to behavioural and brain neurochemical alterations in C57BL/6J and BALB/c mice [PDF]
Epidemiological evidence suggests that low levels of vitamin D may predispose people to develop depression and cognitive impairment. While rodent studies have demonstrated that prenatal vitamin D deficiency is associated with altered brain development ...
Burne, Thomas H. J. +5 more
core +1 more source

