Effect of deoxyribonuclease I treatment for dementia in end-stage Alzheimer’s disease: a case report
Journal of Medical Case Reports, 2016 BackgroundAlzheimer's disease is the most common cause of dementia and is characterized by a progressive loss of brain tissue leading to amyloid-β accumulation and severe decline in cognitive function.
V. Tetz, G. Tetz
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A novel role for synaptic acetylcholinesterase as an apoptotic deoxyribonuclease
Cell Discovery, 2015 In addition to terminating neurotransmission by hydrolyzing acetylcholine, synaptic acetylcholinesterase (AChES) has been found to have a pro-apoptotic role. However, the underlying mechanism has rarely been investigated.
Aiying Du +10 more
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Isolation and Sequence Analyses of Salinity Tolerance Genes from Bruguiera Cylindrica (L.) Blume [PDF]
, 2005 Salinity is a major abiotic stress limiting the productivity of crop plants globally. The discovery of novel genes in stress adaptation will provide effective genetic engineering strategies leading to g reater stress tolerance.
Wong, Yeen Yee
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Characterization of Expressed Genes Isolated From Oil Palm Vegetative, Normal and Abnormal Inflorescence Meristems Using EST Approach [PDF]
, 2003 Little is known about the function of genes expressed in oil palm vegetative meristem tissues, which are expressed during transition from vegetative to reproductive growth, and those expressed during the formation of abnormal inflorescence. This study
Lee, Yang Ping
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Phosphatidic acid counteracts S-RNase signaling in pollen by stabilizing the actin cytoskeleton [PDF]
, 2018 S-RNase is the female determinant of self-incompatibility (SI) in pear (Pyrus bretschneideri). After translocation to the pollen tube, S-RNase degrades rRNA and induces pollen tube death in an S-haplotype-specific manner. In this study, we found that the
Chen, Jianqing +7 more
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Type II restriction endonucleases : a historical perspective and more [PDF]
, 2014 This article continues the series of Surveys and Summaries on restriction endonucleases (REases) begun this year in Nucleic Acids Research. Here we discuss Type II REases, the kind used for DNA analysis and cloning. We focus on their biochemistry: what
Pingoud, Alfred +2 more
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Mediators of Inflammation, 2012 Introduction. Neutrophil extracellular traps (NET) consist of a DNA scaffold that can be destroyed by Deoxyribonuclease (DNase). Thus DNases are potential prerequisites for natural counter regulation of NETs formation. In the present study, we determined
W. Meng +6 more
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Development of a Recombinant Retrovirus Expressing the Chicken Anaemia Virus Vp3 Protein [PDF]
, 2006 Retrovirus is an infectious particle, hence it could be used as an efficient vector to deliver a desired gene product into mammalian cells. In this study, a recombinant viral vector was employed to carry a gene that induces apoptosis in various ...
Mohd Saad, Suria
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Identification and functional characterization of protein domains in the transcription factor TWIST [PDF]
, 2006 Saethre-Chotzen syndrome is an autosomal dominant inherited disorder with premature fusion of cranial sutures. It is caused by nucleotide sequence changes within or in proximity of the TWIST1 gene. This gene encodes for a bHLH transcription factor, which
Kunz, Jürgen (Dr.), Singh, Shalini
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Incompetence of Neutrophils to Invasive Group A streptococcus Is Attributed to Induction of Plural Virulence Factors by Dysfunction of a Regulator [PDF]
, 2008 Group A streptococcus (GAS) causes variety of diseases ranging from common pharyngitis to life-threatening severe invasive diseases, including necrotizing fasciitis and streptococcal toxic shock-like syndrome.
A ith +48 more
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