Results 51 to 60 of about 13,337 (203)

Nucleozymes [PDF]

open access: yes, 2004
Nucleozymes containing ribonucleotides and deoxyribonucleotides or nucleic acid analogues are described herein. The nucleozymes have catalytic activity and are significantly more resistant to degradation than their all-RNA ribozyme counterparts.
Cedergren, Robert J.   +4 more
core   +1 more source

Liver regeneration in dogs: Morphologic and chemical changes [PDF]

open access: yes, 1978
Forty-four percent and 72% hepatectomy were carried out in dogs and the animals were sacrificed for biochemical and pathologic studies from 0.5 to 6 days later.
Antonio Francavilla   +34 more
core   +1 more source

Mitochondrial Deoxyribonucleotides, Pool Sizes, Synthesis, and Regulation [PDF]

open access: yesJournal of Biological Chemistry, 2004
We quantify cytosolic and mitochondrial deoxyribonucleoside triphosphates (dNTPs) from four established cell lines using a recently described method for the separation of cytosolic and mitochondrial (mt) dNTPs from as little as 10 million cells in culture (Pontarin, G., Gallinaro, L., Ferraro, P., Reichard, P., and Bianchi, V. (2003) Proc. Natl.
RAMPAZZO, CHIARA   +5 more
openaire   +4 more sources

Calmodulin‐Like Protein MfCML50 Interacts With Carveol Dehydrogenase in Medicago falcata to Regulate Cold Tolerance Through Mediating ROS Homeostasis

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Low temperature triggers Ca2+ signalling and reprogramming of gene expression and metabolism in plants. However, how the Ca2+ signal is transduced to the downstream metabolic pathways remains unknown. The involvement of a cold‐induced calmodulin‐like protein, MfCML50, from Medicago falcata in regulation of cold tolerance was examined in the ...
Bohao Geng   +6 more
wiley   +1 more source

Radiopharmaceuticals for Persistent or Recurrent Uterine Cervix Cancer

open access: yesFrontiers in Oncology, 2019
Uterine cervix cancers pose therapeutic challenges because of an overactive ribonucleotide reductase, which provides on-demand deoxyribonucleotides for DNA replication or for a DNA damage repair response.
Charles A. Kunos   +3 more
doaj   +1 more source

Characterization of a Virally Encoded Flavodoxin That Can Drive Bacterial Cytochrome P450 Monooxygenase Activity

open access: yesBiomolecules, 2022
Flavodoxins are small electron transport proteins that are involved in a myriad of photosynthetic and non-photosynthetic metabolic pathways in Bacteria (including cyanobacteria), Archaea and some algae.
David C. Lamb   +7 more
doaj   +1 more source

Development of Sequence Tagged Microsatellite Site (STMS) markers in Azalea [PDF]

open access: yes
A genomic library was constructed from DNA of two azalea genotypes: a Belgian pot azalea R. simsii hybrid Mevr. Van Belle and a Chinese R. simsii from Daoxian.
Arens, P.   +5 more
core   +2 more sources

Isolation and characterization of a thermophilic, obligately anaerobic and heterotrophic marine Chloroflexi bacterium from a Chloroflexi dominated microbial community associated with a Japanese shallow hydrothermal system, and proposal for Thermomarinilinea lacunofontalis gen. nov., sp. nov. [PDF]

open access: yes, 2013
A novel marine thermophilic and heterotrophic Anaerolineae bacterium in the phylum Chloroflexi, strain SW7T, was isolated from an in situ colonization system deployed in the main hydrothermal vent of the Taketomi submarine hot spring field located on the
FURUSHIMA, Yasuo   +19 more
core   +1 more source

Direct evidence of singlet molecular oxygen [O2 (1Δg)] production from UVA excited 6‐thioguanine

open access: yesPhotochemistry and Photobiology, EarlyView.
6‐Thioguanine (6‐TGua) is incorporated into DNA as a purine analogue, inhibiting cell replication. Patients treated with 6‐TGua are more prone to developing skin cancer due to the photoexcitation of 6‐TGua by UVA radiation (as illustrated in the Jablonski diagram). Upon exposure to UVA, the excited 6‐TGua generates 1O2.
André L. Lopes   +6 more
wiley   +1 more source

Radicals and the Birth and Death of DNA

open access: yesCHIMIA, 2001
Radicals have important functions in the enzymatic synthesis of deoxyribonucleotides and their destruction by antibiotics. The chemical basis for these reactions is that radicals dramatically speed up ionic reactions.
Bernd Giese
doaj   +2 more sources

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