Results 51 to 60 of about 1,276 (149)

Guanine Nucleotide Exchange Factors and Small GTPases: Their Regulation and Functions, Diseases, and Therapeutic Targets

MedComm, Volume 6, Issue 10, October 2025.
This review comprehensively examines the regulatory mechanisms and physiological roles of guanine nucleotide exchange factors (GEFs) and their small GTPase substrates, highlighting their significance in cellular processes and disease pathogenesis.
Zexing Lin, Chujun Ni, Haiyang Jiang, Huan Yang, Liting Deng, Peizhao Liu, Xuanheng Li, Yilong Yu, Weijie Li, Runnan Wang, Bo Liao, Jiaqi Kang, Juanhan Liu, Xiuwen Wu, Jianan Ren, Yun Zhao   +15 more
wiley   +1 more source

HvDep1 Is a Positive Regulator of Culm Elongation and Grain Size in Barley and Impacts Yield in an Environment-Dependent Manner. [PDF]

PLoS ONE, 2016
Heterotrimeric G proteins are intracellular membrane-attached signal transducers involved in various cellular processes in both plants and animals. They consist of three subunits denoted as α, β and γ.
Toni Wendt, Inger Holme, Christoph Dockter, Aileen Preuß, William Thomas, Arnis Druka, Robbie Waugh, Mats Hansson, Ilka Braumann   +8 more
doaj   +1 more source

Genomic dissection of yield components in rice (Oryza sativa L.) using genome‐wide association study and identification of novel genetic factors for yield‐related traits

Agrosystems, Geosciences &Environment, Volume 8, Issue 3, September 2025.
Abstract Genome‐wide association study (GWAS) is a powerful method for understanding the associations between phenotype and genomic variations. Given the growing population, increasing yield of rice as a staple food crop is important. Here, a GWAS with 33,839 single nucleotide polymorphisms (SNPs) was carried out to define genomic regions influencing ...
Rahele Panahabadi, Asadollah Ahmadikhah, Naser Farrokhi, Nadali Bagheri   +3 more
wiley   +1 more source

Unveiling the complexity of cellular senescence in cancers: From mechanism to therapeutic opportunities

BMEMat, Volume 3, Issue 3, September 2025.
This review highlights the complex roles of cellular senescence in cancer progression and suppression, discusses the mechanisms and regulatory pathways involved, and evaluates the efficacy of the “One‐Two punch” sequential treatment approach while addressing emerging challenges in this novel therapeutic strategy.
Qiuming Pan, Ye Zhu, Zhi Ye, Huayang Zhang, Junxi Wang, Guozhong Yi, Zhiyong Li, Rongyang Xu, Luyao Wang, Zhenzhen Wu, Songtao Qi, Guanglong Huang, Shanqiang Qu   +12 more
wiley   +1 more source

Perfect image, depressed mood: Pathways from perfectionistic self‐presentation to depressive symptoms through online and in‐person connectedness among Canadian adolescents

Journal of Research on Adolescence, Volume 35, Issue 3, September 2025.
Abstract The Perfectionism Social Disconnection Model (PSDM) contends that perfectionism predicts psychopathology via social disconnection and has received support in adult and adolescent samples. However, little is known about the role of online connection.
Melissa Blackburn, Danielle S. Molnar, Dawn Zinga   +2 more
wiley   +1 more source

The DENSE AND ERECT PANICLE 1 (DEP1) gene offering the potential in the breeding of high-yielding rice.

Breeding science, 2016
The erect panicle model super-rice can rationally transform the solar energy into accumulated organic matter (biomass) and increase grain yield. The phenotype of erect panicle architecture controlled by DENSE AND ERECT PANICLE 1 (DEP1) has been used in rice breeding for nearly a century owing to its high-yield, lodging tolerance with strong stem ...
Xu, Hai, Zhao, Minghui, Zhang, Qun, Xu, Zhengjin, Xu, Quan   +4 more
openaire   +2 more sources

Dissecting combining ability effect in a rice NCII-III population provides insights into heterosis in indica-japonica cross

Rice, 2017
Background Combining ability is a measure for selecting elite parents that make the highest contributions to hybrid performance. However, the genetic bases of combining ability and how they contributed to heterosis is seldomly known.
Hao Zhou, Duo Xia, Jing Zeng, Gonghao Jiang, Yuqing He   +4 more
doaj   +1 more source

Replacements at Structural or Functional Dimorphisms 103, 109 and 167 Distinguish HLA Class I Serologically Defined Antigens

HLA, Volume 106, Issue 3, September 2025.
ABSTRACT Amino acid variations in the HLA molecule may serve as part of serologic epitopes (residues determining epitopes: DEP) detected by allo‐antibodies. In current clinical histocompatibility practices, the presence of anti‐HLA donor‐specific antibodies (DSA) is assessed by solid phase (SP) tests with single antigen bead (SAB) panels. The antigenic
Kazutoyo Osoegawa, Jellina Son, Kenneth Yim, Steven G. E. Marsh, Marcelo A. Fernández Viňa   +4 more
wiley   +1 more source

A Novel OsMPK6‐OsMADS47‐PPKL1/3 Module Controls Grain Shape and Yield in Rice

Advanced Science, Volume 12, Issue 30, August 14, 2025.
OsMADS47 is identified as a key regulator governing rice grain morphology. Phosphorylation‐dependent regulation of its activity directs the development of slender versus round grains, modulating both yield and appearance. This mechanism bridges cellular signaling with transcriptional regulation, establishing a molecular framework for grain optimization.
Jingjing Fang, Yan Chun, Fan Zhang, Tingting Guo, Mengmeng Ren, Jinfeng Zhao, Shoujiang Yuan, Wensheng Wang, Yunhai Li, Xueyong Li   +9 more
wiley   +1 more source

Balance hídrico en regiones cafeteras mediante el déficit de evaporación

Tecnología y ciencias del agua
La zonificación del área cafetera mexicana se realiza de forma geográfica, pero dada la diversidad climática de esta, dicha clasificación difícilmente capta la homogeneidad ambiental y no representa las condiciones adaptativas del cultivo.
Fernando Reyes-González, Arturo Galvis-Spinola, Teresa Marcela Hernández-Mendoza, Juan José Almaraz-Suárez, Alejandro Alarcón   +4 more
doaj   +1 more source