Results 71 to 80 of about 1,305,054 (323)

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Shunting passenger trains: getting ready for departure [PDF]

, 2008
In this paper we consider the problem of shunting train units on a railway station. Train units arrive at and depart from the station according to a given train schedule and in between the units may have to be stored at the station.
Akker, Marjan van den, Baarsma, Hilbrandt, Hurink, Johann, Modelski, Maciej, Paulus, Jacob Jan, Reijnen, Ingrid, Roozemond, Dan, Schreuder, Jan   +7 more
core   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman, Tadi Hondonga, Alison Berry, Caitlin Elgarten, Jason Freedman, Katelyn Oranges, Sara McDonough, Caroline Diorio, L. Lee Dupuis   +8 more
wiley   +1 more source

Airline planning benchmark problems—Part II : passenger groups, utility and demand allocation [PDF]

, 2013
This paper is the second of two papers entitled “Airline Planning Benchmark Problems”, aimed at developing benchmark data that can be used to stimulate innovation in airline planning, in particular, in flight schedule design and fleet assignment.
Akartunali, Kerem, Boland, Natashia, Evans, Ian, Wallace, Mark, Waterer, Hamish   +4 more
core   +1 more source

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source

How highly does the freight transport industry value journey time reliability - and for what reasons?

, 2004
Delays to road freight vehicles impose a very high cost on the nation. Delayed arrival time can occur for a variety of reasons. This paper presents the findings of a Highways Agency funded study, which has investigated the user valuations of three ...
Firmin, P.E., Fowkes, A.S., Tweddle, G., Whiteing, A.E.   +3 more
core   +1 more source

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle, Kiersten Ricci, Kelly Blache, Rebecca A. Marsh, Adrienne M. Hammill, Elissa Engel   +5 more
wiley   +1 more source

The Peculiarities of Obtaining a Parents Consent (Legal Representative’s) to the Departure of a Minorfrom the Russian Federation

Сибирское юридическое обозрение, 2019
The analysis of the current legislation regulating the procedure for the entry and exit of minors outside the Russian Federation has been carried out, the features of obtaining consent for the departure of a minor outside the Russian Federation have been
Y. O. Petrova
doaj   +1 more source

A test for second-order stationarity of time series based on unsystematic sub-samples [PDF]

, 2016
In this paper, we introduce a new method for testing the stationarity of time series, where the test statistic is obtained from measuring and maximising the difference in the second-order structure over pairs of randomly drawn intervals.
Cho, Cho, Cho, Dahlhaus, Dette, Fryzlewicz, Fryzlewicz, Fryzlewicz, Jin, Kreiss, Nason, Nason, Neumann, Neumann, Ombao, Paparoditis, Paparoditis, Preuß, Priestley, Puchstein, Van Bellegem, von Sachs   +21 more
core   +3 more sources