Results 71 to 80 of about 214,245 (305)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Investigation of Amazon and Google for Fault Tolerance Strategies in Cloud Computing Services

open access: yesOnline Academic Journal of Information Technology, 2016
Cloud computing has recently become an attractive topic due to its ability to offer information technology solutions through virtual machines as on-demand services to share and consume resources over the Internet.
Sinan Can Açan, Shereen Al-raheym
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Technological reliability of chemical engineering systems

open access: yesТонкие химические технологии, 2016
A significant part of the gross domestic product is lost because of hitches followed by long downtime periods in industrial systems. This is a common problem in the industry of developed nations.
N. N. Prokhorenko, K. O. Goncharuk
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Formal Dependability Engineering with MIOA [PDF]

open access: yes, 2008
In this paper, we introduce MIOA, a stochastic process algebra-like specification language with datatypes, as well as a logic intSPDL, and its model checking algorithms.
Haverkort, Boudewijn, Kuntz, Matthias
core   +2 more sources

Model-based dependability analysis : state-of-the-art, challenges and future outlook [PDF]

open access: yes, 2015
: Over the past two decades, the study of model-based dependability analysis has gathered significant research interest. Different approaches have been developed to automate and address various limitations of classical dependability techniques to contend
Kabir, Sohag   +3 more
core   +2 more sources

A High‐Sensitivity Circulating Nucleic Acid Sequencing Assay for Assessing Treatment Response to Alectinib in a Pediatric Patient With ALK‐Rearranged Non–Small Cell Lung Cancer

open access: yes
Pediatric Blood &Cancer, EarlyView.
Alberto D. Guerra   +9 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Resilience-by-Design in 6G Networks: Literature Review and Novel Enabling Concepts

open access: yesIEEE Access
The sixth generation (6G) mobile communication networks are expected to intelligently integrate into various aspects of modern digital society, including smart cities, homes, health-care, transportation, and factories.
Ladan Khaloopour   +14 more
doaj   +1 more source

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