Results 141 to 150 of about 9,392,573 (389)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Codifference can detect ergodicity breaking and non-Gaussianity

open access: yesNew Journal of Physics, 2019
We show that the codifference is a useful tool in studying the ergodicity breaking and non-Gaussianity properties of stochastic time series. While the codifference is a measure of dependence that was previously studied mainly in the context of stable ...
Jakub Ślęzak   +2 more
doaj   +1 more source

The relationship between childhood trauma and drug dependence at an in-patient treatment centre in the Western Cape [PDF]

open access: yes, 2013
Magister Psychologiae - MPsychThe outcome of child abuse, i.e. physical, emotional and/or sexual, and child neglect is multifactorial. The severity, duration and nature of abuse and the child’s vulnerabilities are all contributory factors with regards ...
Gerber, Wynand
core  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Information theoretic measures of dependence, compactness, and non-gaussianity for multivariate probability distributions [PDF]

open access: yesNonlinear Processes in Geophysics, 2009
A basic task of exploratory data analysis is the characterisation of "structure" in multivariate datasets. For bivariate Gaussian distributions, natural measures of dependence (the predictive relationship between individual variables) and ...
A. H. Monahan, T. DelSole
doaj  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Heterogeneity or True State Dependence in Poverty - The tale told by twins

open access: yes
This study focuses on the persistence of poverty in Sweden. The purpose is to distinguish between two different reasons why poverty could persist on an individual level.
Nilsson, William
core  

A new (multivariate) copula-based measure of dependence and some additional results in dependence modelling

open access: yes, 2022
Estimating scale-invariant directed dependence of bivariate distributions Robert R. Junker, Florian Griessenberger, Wolfgang TrutschnigOn a multivariate copula-based dependence measure and its estimation Florian Griessenberger, Robert R. Junker, Wolfgang
Griessenberger, Florian
core  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

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