FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Dating Violence, Emotional Dependence and Mental Health Problems in Ecuadorian College Students. [PDF]
Healthcare (Basel)Castillo-Gonzáles M +3 more
europepmc +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
On the relationship between efficiency and cooperativity in multi-subunit molecular machines. [PDF]
Protein SciBen-Maimon M, Horovitz A.
europepmc +1 more source
FEBS Open Bio, EarlyView.We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa +2 more
wiley +1 more source
Validity, Reliability and Responsiveness of Wound-QoL-14 Quality of Life Questionnaire in Patients With Diabetes Related Foot Ulcers. [PDF]
Int Wound JHitchman L +7 more
europepmc +1 more source
Affective Factors in the Co-Occurrence of Personality Disorders and Substance Use Disorders. [PDF]
Curr Addict RepWycoff AM, Trull TJ.
europepmc +1 more source
Prior Trial Effects on Working Memory in Schizophrenia, Bipolar Disorder, and Healthy Control Individuals. [PDF]
JAMA PsychiatryBansal S +7 more
europepmc +1 more source
Squeezing, trisqueezing and quadsqueezing in a hybrid oscillator-spin system. [PDF]
Nat PhysBăzăvan O +9 more
europepmc +1 more source