Results 61 to 70 of about 3,753,934 (302)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Subjective Measure of Car Dependence

open access: yes, 2011
A subjective measure of car dependence was developed on the basis of people's own assessment of their reliance on car use. The measure supplements the commonly used objective measure on the basis of actual car use. Structural equation models (SEMs) were
Jinhua Zhao
core   +1 more source

Optimal distributed sensing in noisy environments

open access: yesPhysical Review Research, 2020
We consider distributed sensing of nonlocal quantities. We introduce quantum enhanced protocols to directly measure any (scalar) field with a specific spatial dependence by placing sensors at appropriate positions and preparing a spatially distributed ...
P. Sekatski, S. Wölk, W. Dür
doaj   +1 more source

ON AN INTERNAL DEPENDENCE OF SIMULTANEOUS MEASUREMENTS

open access: yes, 2023
In this paper we show that there exists an internal dependence of the simultaneous measurements made by the two pairs of linear polarizers operated in each leg of the apparatus in Aspect’s version of Einstein-Podolsky-Rosen Gedankenexperiment. The corresponding Shannon-Kolmogorov’s information flow linking a polarizer from one leg to a polarizer from ...
openaire   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Letter From the Editor [PDF]

open access: yes, 2022
Letter From the Editor, Meagan Edwards, introducing Volume 6 of The ...
Meagan Edwards
core   +1 more source

PAM clustering algorithm based on mutual information matrix for ATR-FTIR spectral feature selection and disease diagnosis

open access: yesBMC Medical Research Methodology
The ATR-FTIR spectral data represent a valuable source of information in a wide range of pathologies, including neurological disorders, and can be used for disease discrimination. To this end, the identification of the potential spectral biomarkers among
Francesca Condino   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

A measure of mutual complete dependence [PDF]

open access: yes, 2007
Two random variables X and Y are mutually completely dependent (m.c.d.) if there is a measurable bijection f with P(Y = f(X)) = 1. For continuous X and Y , a natural approach to constructing a measure of dependence is via the distance between the ...
Siburg, Karl Friedrich   +2 more
core   +1 more source

Home - About - Disclaimer - Privacy