Results 191 to 200 of about 841,861 (265)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Synthetic lethality between RB-loss and E2F3 inhibition in small cell cancers targeted by pyrimidine synthesis blockade. [PDF]

open access: yesProc Natl Acad Sci U S A
Abt ER   +16 more
europepmc   +1 more source

IRS4 is a PI3K-activating cancer dependency up-regulated through DNA rearrangements or epigenetic mechanisms in multiple solid tumors. [PDF]

open access: yesSci Adv
Banu K   +21 more
europepmc   +1 more source

Biomedical open source software: Crucial packages and hidden heroes. [PDF]

open access: yesPLoS Comput Biol
Brown EM   +7 more
europepmc   +1 more source

Halothane dependence

open access: yesIndustrial Psychiatry Journal
Dhamija, Sana   +2 more
openaire   +2 more sources

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