Results 111 to 120 of about 7,180,624 (308)
The Merit-based Incentive Payment System: Pearson's Chi-Square and Categorical Dependent Variable Models Analyzed for Domains-Effective Clinical Care and Efficiency/Cost Reduction. [PDF]
J Health Econ Outcomes Res, 2021 Shenoy A.
europepmc +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Results in PhysicsIn this article, we present a nonlinear model of the Liu system that includes fractional derivatives of variable-order. Due to the nonlocality of the dynamical system, we introduce the fractional derivative with power laws, exponential decay laws, and ...
Khalid I.A. Ahmed +3 more
doaj +1 more source
On the characteristic function of a sum of M-dependent random variables
International Journal of Mathematics and Mathematical Sciences, 1986 Let S=f1+f2+…+fn be a sum of 1-dependent random variables of zero mean. Let σ2=ES2, L=σ−3∑1≦i≦nE|fi|3.
Wansoo T. Rhee
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Estimation of the Medians for Dependent Variables
The Annals of Mathematical Statistics, 1959 Joint intervals of bounded confidence are suggested for the medians of a bivariate population with continuous marginal distributions. The two intervals are of the classic type based on sample order statistics.
openaire +3 more sources
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Step-wise regression with RTs as dependent variable.
, 2018 Step-wise regression with RTs as dependent variable.
Antonio M. Díez-Álamo (5005586) +3 more
core +1 more source